PINK1-Associated Parkinson's Disease Is Caused by Neuronal Vulnerability to Calcium-Induced Cell Death

por Gandhi, Sonia, Wood-Kaczmar, Alison, Yao, Zhi, Plun-Favreau, Helene, Deas, Emma, Klupsch, Kristina, Downward, Julian, Latchman, David S., Tabrizi, Sarah J., Wood, Nicholas W., Duchen, Michael R., Abramov, Andrey Y.
Publicado 2009

Ca(2+) is a key factor in α-synuclein-induced neurotoxicity

por Angelova, Plamena R., Ludtmann, Marthe H. R., Horrocks, Mathew H., Negoda, Alexander, Cremades, Nunilo, Klenerman, David, Dobson, Christopher M., Wood, Nicholas W., Pavlov, Evgeny V., Gandhi, Sonia, Abramov, Andrey Y.
Publicado 2016

Diabetes and Neuroaxonal Damage in Parkinson's Disease

por Vijiaratnam, Nirosen, Lawton, Michael, Real, Raquel, Heslegrave, Amanda J., Guo, Tong, Athauda, Dilan, Gandhi, Sonia, Girges, Christine, Ben‐Shlomo, Yoav, Zetterberg, Henrik, Grosset, Donald G., Morris, Huw R., Foltynie, Thomas
Publicado 2022

The Impact of Type 2 Diabetes in Parkinson's Disease

por Athauda, Dilan, Evans, James, Wernick, Anna, Virdi, Gurvir, Choi, Minee L., Lawton, Michael, Vijiaratnam, Nirosen, Girges, Christine, Ben‐Shlomo, Yoav, Ismail, Khalida, Morris, Huw, Grosset, Donald, Foltynie, Thomas, Gandhi, Sonia
Publicado 2022

PINK1 cleavage at position A103 by the mitochondrial protease PARL

por Deas, Emma, Plun-Favreau, Helene, Gandhi, Sonia, Desmond, Howard, Kjaer, Svend, Loh, Samantha H.Y., Renton, Alan E.M., Harvey, Robert J., Whitworth, Alexander J., Martins, L. Miguel, Abramov, Andrey Y., Wood, Nicholas W.
Publicado 2011

Correction to ‘Bifunctional fluorescent probes for detection of amyloid aggregates and reactive oxygen species’

por Needham, Lisa-Maria, Weber, Judith, Fyfe, James W. B., Kabia, Omaru M., Do, Dung T., Klimont, Ewa, Zhang, Yu, Rodrigues, Margarida, Dobson, Christopher M., Gandhi, Sonia, Bohndiek, Sarah E., Snaddon, Thomas N., Lee, Steven F.
Publicado 2018

Towards a multi-arm multi-stage platform trial of disease modifying approaches in Parkinson’s disease

por Foltynie, Tom, Gandhi, Sonia, Gonzalez-Robles, Cristina, Zeissler, Marie-Louise, Mills, Georgia, Barker, Roger, Carpenter, James, Schrag, Anette, Schapira, Anthony, Bandmann, Oliver, Mullin, Stephen, Duffen, Joy, McFarthing, Kevin, Chataway, Jeremy, Parmar, Mahesh, Carroll, Camille
Publicado 2023

Single-Molecule Imaging of Individual Amyloid Protein Aggregates in Human Biofluids

por Horrocks, Mathew H., Lee, Steven F., Gandhi, Sonia, Magdalinou, Nadia K., Chen, Serene W., Devine, Michael J., Tosatto, Laura, Kjaergaard, Magnus, Beckwith, Joseph S., Zetterberg, Henrik, Iljina, Marija, Cremades, Nunilo, Dobson, Christopher M., Wood, Nicholas W., Klenerman, David
Publicado 2016

Alpha-Synuclein Oligomers Interact with Metal Ions to Induce Oxidative Stress and Neuronal Death in Parkinson's Disease

por Deas, Emma, Cremades, Nunilo, Angelova, Plamena R., Ludtmann, Marthe H.R., Yao, Zhi, Chen, Serene, Horrocks, Mathew H., Banushi, Blerida, Little, Daniel, Devine, Michael J., Gissen, Paul, Klenerman, David, Dobson, Christopher M., Wood, Nicholas W., Gandhi, Sonia, Abramov, Andrey Y.
Publicado 2016

Pandemic peak SARS-CoV-2 infection and seroconversion rates in London frontline health-care workers

por Houlihan, Catherine F, Vora, Nina, Byrne, Thomas, Lewer, Dan, Kelly, Gavin, Heaney, Judith, Gandhi, Sonia, Spyer, Moira J, Beale, Rupert, Cherepanov, Peter, Moore, David, Gilson, Richard, Gamblin, Steve, Kassiotis, George, McCoy, Laura E, Swanton, Charles, Hayward, Andrew, Nastouli, Eleni
Publicado 2020

Tau acts as an independent genetic risk factor in pathologically proven PD

por Charlesworth, Gavin, Gandhi, Sonia, Bras, Jose M., Barker, Roger A., Burn, David J., Chinnery, Patrick F., Gentleman, Stephen M., Guerreiro, Rita, Hardy, John, Holton, Janice L., Lees, Andrew, Morrison, Karen, Sheerin, Una-Marie, Williams, Nigel, Morris, Huw, Revesz, Tamas, Wood, Nicholas W.
Publicado 2012

Inhibiting the Ca(2+) Influx Induced by Human CSF

por Drews, Anna, De, Suman, Flagmeier, Patrick, Wirthensohn, David C., Chen, Wei-Hsin, Whiten, Daniel R., Rodrigues, Margarida, Vincke, Cécile, Muyldermans, Serge, Paterson, Ross W., Slattery, Catherine F., Fox, Nick C., Schott, Jonathan M., Zetterberg, Henrik, Dobson, Christopher M., Gandhi, Sonia, Klenerman, David
Publicado 2017

Nanoscopic Characterisation of Individual Endogenous Protein Aggregates in Human Neuronal Cells

por Whiten, Daniel R., Zuo, Yukun, Calo, Laura, Choi, Minee‐Liane, De, Suman, Flagmeier, Patrick, Wirthensohn, David C., Kundel, Franziska, Ranasinghe, Rohan T., Sanchez, Santiago E., Athauda, Dilan, Lee, Steven F., Dobson, Christopher M., Gandhi, Sonia, Spillantini, Maria‐Grazia, Klenerman, David, Horrocks, Mathew H.
Publicado 2018

Omicron neutralising antibodies after COVID-19 vaccination in haemodialysis patients

por Carr, Edward J, Wu, Mary, Harvey, Ruth, Billany, Roseanne E, Wall, Emma C, Kelly, Gavin, Howell, Michael, Kassiotis, George, Swanton, Charles, Gandhi, Sonia, Bauer, David LV, Graham-Brown, Matthew PM, Jones, Rachel B, Smith, Rona M, McAdoo, Stephen, Willicombe, Michelle, Beale, Rupert
Publicado 2022

Two-color coincidence single-molecule pulldown for the specific detection of disease-associated protein aggregates

por Saleeb, Rebecca S., Leighton, Craig, Lee, Ji-Eun, O’Shaughnessy, Judi, Jeacock, Kiani, Chappard, Alexandre, Cumberland, Robyn, Zhao, Tianxiao, Ball, Sarah R., Sunde, Margaret, Clarke, David J., Piché, Kristin, McPhail, Jacob A., Louwrier, Ariel, Angers, Rachel, Gandhi, Sonia, Downey, Patrick, Kunath, Tilo, Horrocks, Mathew H.
Publicado 2023

PINK1 Is Necessary for Long Term Survival and Mitochondrial Function in Human Dopaminergic Neurons

por Wood-Kaczmar, Alison, Gandhi, Sonia, Yao, Zhi, Abramov, Andrey S. Y., Miljan, Erik A., Keen, Gregory, Stanyer, Lee, Hargreaves, Iain, Klupsch, Kristina, Deas, Emma, Downward, Julian, Mansfield, Louise, Jat, Parmjit, Taylor, Joanne, Heales, Simon, Duchen, Michael R., Latchman, David, Tabrizi, Sarah J., Wood, Nicholas W.
Publicado 2008

Correction: PINK1 Is Necessary for Long Term Survival and Mitochondrial Function in Human Dopaminergic Neurons

por Wood-Kaczmar, Alison, Gandhi, Sonia, Yao, Zhi, Abramov, Andrey Y., Miljan, Erik A., Keen, Gregory, Stanyer, Lee, Hargreaves, Iain, Klupsch, Kristina, Deas, Emma, Downward, Julian, Mansfield, Louise, Jat, Parmjit, Taylor, Joanne, Heales, Simon, Duchen, Michael R., Latchman, David, Tabrizi, Sarah J., Wood, Nicholas W.
Publicado 2008

Correction: PINK1 Is Necessary for Long Term Survival and Mitochondrial Function in Human Dopaminergic Neurons

por Wood-Kaczmar, Alison, Gandhi, Sonia, Yao, Zhi, Abramov, Andrey Y., Miljan, Erik A., Keen, Gregory, Stanyer, Lee, Hargreaves, Iain, Klupsch, Kristina, Deas, Emma, Downward, Julian, Mansfield, Louise, Jat, Parmjit, Taylor, Joanne, Heales, Simon, Duchen, Michael R., Latchman, David, Tabrizi, Sarah J., Wood, Nicholas W.
Publicado 2008

WHO's Therapeutics and COVID-19 Living Guideline on mAbs needs to be reassessed

por Wu, Mary Y, Carr, Edward J, Harvey, Ruth, Mears, Harriet V, Kjaer, Svend, Townsley, Hermaleigh, Hobbs, Agnieszka, Ragno, Martina, Herman, Lou S, Adams, Lorin, Gamblin, Steve, Howell, Michael, Beale, Rupert, Brown, Michael, Williams, Bryan, Gandhi, Sonia, Swanton, Charles, Wall, Emma C, Bauer, David L V
Publicado 2023

Alpha synuclein aggregation drives ferroptosis: an interplay of iron, calcium and lipid peroxidation

por Angelova, Plamena R., Choi, Minee L., Berezhnov, Alexey V., Horrocks, Mathew H., Hughes, Craig D., De, Suman, Rodrigues, Margarida, Yapom, Ratsuda, Little, Daniel, Dolt, Karamjit S., Kunath, Tilo, Devine, Michael J., Gissen, Paul, Shchepinov, Mikhail S., Sylantyev, Sergiy, Pavlov, Evgeny V., Klenerman, David, Abramov, Andrey Y., Gandhi, Sonia
Publicado 2020