1506. Burden of Respiratory Syncytial Virus (RSV) and Other Lower Respiratory Tract Viral Infections During the First Two Years of Life: a Prospective Study

por Madhi, Shabir A, Ceballos, Ana, Colas, Jo Ann, Cousin, Luis, D’Andrea, Ulises, Dieussaert, Ilse, Domachowske, Joseph B, Englund, Janet A, Gandhi, Sanjay, Haars, Gerco, Hercor, Mélanie, de Heusch, Magali, Jose, Lisa, Langley, Joanne M, Leach, Amanda, Silas, Peter, Teeratakulpisarn, Jamaree, Vesikari, Timo, Stoszek, Sonia K
Publicado 2020

Nanobodies raised against monomeric ɑ-synuclein inhibit fibril formation and destabilize toxic oligomeric species

por Iljina, Marija, Hong, Liu, Horrocks, Mathew H., Ludtmann, Marthe H., Choi, Minee L., Hughes, Craig D., Ruggeri, Francesco S., Guilliams, Tim, Buell, Alexander K., Lee, Ji-Eun, Gandhi, Sonia, Lee, Steven F., Bryant, Clare E., Vendruscolo, Michele, Knowles, Tuomas P. J., Dobson, Christopher M., De Genst, Erwin, Klenerman, David
Publicado 2017

Mitochondrial dysfunction is a key pathological driver of early stage Parkinson’s

por Toomey, Christina E., Heywood, Wendy E., Evans, James R., Lachica, Joanne, Pressey, Sarah N., Foti, Sandrine C., Al Shahrani, Mesfer, D’Sa, Karishma, Hargreaves, Iain P., Heales, Simon, Orford, Michael, Troakes, Claire, Attems, Johannes, Gelpi, Ellen, Palkovits, Miklos, Lashley, Tammaryn, Gentleman, Steve M., Revesz, Tamas, Mills, Kevin, Gandhi, Sonia
Publicado 2022

Clinical outcomes of COVID-19 in long-term care facilities for people with epilepsy

por Balestrini, Simona, Koepp, Matthias J., Gandhi, Sonia, Rickman, Hannah M., Shin, Gee Yen, Houlihan, Catherine F., Anders-Cannon, Jonny, Silvennoinen, Katri, Xiao, Fenglai, Zagaglia, Sara, Hudgell, Kirsty, Ziomek, Mariusz, Haimes, Paul, Sampson, Adam, Parker, Annie, Helen Cross, J., Pardington, Rosemarie, Nastouli, Eleni, Swanton, Charles, Sander, Josemir W., Sisodiya, Sanjay M.
Publicado 2021

AZD1222-induced neutralising antibody activity against SARS-CoV-2 Delta VOC

por Wall, Emma C, Wu, Mary, Harvey, Ruth, Kelly, Gavin, Warchal, Scott, Sawyer, Chelsea, Daniels, Rodney, Adams, Lorin, Hobson, Philip, Hatipoglu, Emine, Ngai, Yenting, Hussain, Saira, Ambrose, Karen, Hindmarsh, Steve, Beale, Rupert, Riddell, Andrew, Gamblin, Steve, Howell, Michael, Kassiotis, George, Libri, Vincenzo, Williams, Bryan, Swanton, Charles, Gandhi, Sonia, Bauer, David LV
Publicado 2021

Neutralising antibody activity against SARS-CoV-2 VOCs B.1.617.2 and B.1.351 by BNT162b2 vaccination

por Wall, Emma C, Wu, Mary, Harvey, Ruth, Kelly, Gavin, Warchal, Scott, Sawyer, Chelsea, Daniels, Rodney, Hobson, Philip, Hatipoglu, Emine, Ngai, Yenting, Hussain, Saira, Nicod, Jerome, Goldstone, Robert, Ambrose, Karen, Hindmarsh, Steve, Beale, Rupert, Riddell, Andrew, Gamblin, Steve, Howell, Michael, Kassiotis, George, Libri, Vincenzo, Williams, Bryan, Swanton, Charles, Gandhi, Sonia, Bauer, David LV
Publicado 2021

2855. Respiratory Syncytial Virus Neutralizing Antibodies in Cord Blood and Serum from Infants up to 2 Years of Age in a Multinational Prospective Study

por Domachowske, Joseph B, Bianco, Veronique, Ceballos, Ana, Cousin, Luis, D’Andrea, Ulises, Dieussaert, Ilse, Englund, Janet A, Gandhi, Sanjay, Haars, Gerco, Jose, Lisa, Klein, Nicola, Marie. Langley, Joanne, Leach, Amanda, Madhi, Shabir A, Maleux, Koen, Lien-Anh Nguyen, Thi, Puthanakit, Thanyawee, Silas, Peter, Stoszek, Sonia K, Tangsathapornpong, Auchara, Teeratakulpisarn, Jamaree, Virta, Miia, Zaman, Khalequ
Publicado 2019

Evaluation of Clinical Case Definitions for Respiratory Syncytial Virus Lower Respiratory Tract Infection in Young Children

por Englund, Janet A, Cohen, Rachel A, Bianco, Veronique, Domachowske, Joseph B, Langley, Joanne M, Madhi, Shabir A, Zaman, Khalequ, Bueso, Agustin, Ceballos, Ana, Cousin, Luis, Gandhi, Sanjay, Gruselle, Olivier, Jose, Lisa, Klein, Nicola P, Koen, Anthonet, Puthanakit, Thanyawee, Shi, Meng, Silas, Peter, Tangsathapornpong, Auchara, Teeratakulpisarn, Jamaree, Vesikari, Timo, Haars, Gerco, Leach, Amanda, Stoszek, Sonia K, Dieussaert, Ilse
Publicado 2023

Within-host SARS-CoV-2 viral kinetics informed by complex life course exposures reveals different intrinsic properties of Omicron and Delta variants

por Russell, Timothy W., Townsley, Hermaleigh, Abbott, Sam, Hellewell, Joel, Carr, Edward J, Chapman, Lloyd, Pung, Rachael, Quilty, Billy J., Hodgson, David, Fowler, Ashley S, Adams, Lorin, Bailey, Christopher, Mears, Harriet V, Harvey, Ruth, Clayton, Bobbi, O’Reilly, Nicola, Ngai, Yenting, Nicod, Jerome, Gamblin, Steve, Williams, Bryan, Gandhi, Sonia, Swanton, Charles, Beale, Rupert, Bauer, David LV, Wall, Emma C, Kucharski, Adam
Publicado 2023

Neutralising antibodies after COVID-19 vaccination in UK haemodialysis patients

por Carr, Edward J, Wu, Mary, Harvey, Ruth, Wall, Emma C, Kelly, Gavin, Hussain, Saira, Howell, Michael, Kassiotis, George, Swanton, Charles, Gandhi, Sonia, Bauer, David LV, Billany, Roseanne E, Graham-Brown, Matthew PM, Beckett, Joseph, Bull, Katherine, Shankar, Sushma, Henderson, Scott, Motallebzadeh, Reza, Salama, Alan D, Harper, Lorraine, Mark, Patrick B, McAdoo, Stephen, Willicombe, Michelle, Beale, Rupert
Publicado 2021

Three-dose vaccination elicits neutralising antibodies against omicron

por Wu, Mary, Wall, Emma C, Carr, Edward J, Harvey, Ruth, Townsley, Hermaleigh, Mears, Harriet V, Adams, Lorin, Kjaer, Svend, Kelly, Gavin, Warchal, Scott, Sawyer, Chelsea, Kavanagh, Caitlin, Queval, Christophe J, Ngai, Yenting, Hatipoglu, Emine, Ambrose, Karen, Hindmarsh, Steve, Beale, Rupert, Gamblin, Steve, Howell, Michael, Kassiotis, George, Libri, Vincenzo, Williams, Bryan, Gandhi, Sonia, Swanton, Charles, Bauer, David LV
Publicado 2022

Progressive Motor Neuron Pathology and the Role of Astrocytes in a Human Stem Cell Model of VCP-Related ALS

por Hall, Claire E., Yao, Zhi, Choi, Minee, Tyzack, Giulia E., Serio, Andrea, Luisier, Raphaelle, Harley, Jasmine, Preza, Elisavet, Arber, Charlie, Crisp, Sarah J., Watson, P. Marc D., Kullmann, Dimitri M., Abramov, Andrey Y., Wray, Selina, Burley, Russell, Loh, Samantha H.Y., Martins, L. Miguel, Stevens, Molly M., Luscombe, Nicholas M., Sibley, Christopher R., Lakatos, Andras, Ule, Jernej, Gandhi, Sonia, Patani, Rickie
Publicado 2017

α-synuclein oligomers interact with ATP synthase and open the permeability transition pore in Parkinson’s disease

por Ludtmann, Marthe H. R., Angelova, Plamena R., Horrocks, Mathew H., Choi, Minee L., Rodrigues, Margarida, Baev, Artyom Y., Berezhnov, Alexey V., Yao, Zhi, Little, Daniel, Banushi, Blerida, Al-Menhali, Afnan Saleh, Ranasinghe, Rohan T., Whiten, Daniel R., Yapom, Ratsuda, Dolt, Karamjit Singh, Devine, Michael J., Gissen, Paul, Kunath, Tilo, Jaganjac, Morana, Pavlov, Evgeny V., Klenerman, David, Abramov, Andrey Y., Gandhi, Sonia
Publicado 2018

Incidence of Respiratory Syncytial Virus Lower Respiratory Tract Infections During the First 2 Years of Life: A Prospective Study Across Diverse Global Settings( )

por Langley, Joanne M, Bianco, Veronique, Domachowske, Joseph B, Madhi, Shabir A, Stoszek, Sonia K, Zaman, Khalequ, Bueso, Agustin, Ceballos, Ana, Cousin, Luis, D’Andrea, Ulises, Dieussaert, Ilse, Englund, Janet A, Gandhi, Sanjay, Gruselle, Olivier, Haars, Gerco, Jose, Lisa, Klein, Nicola P, Leach, Amanda, Maleux, Koen, Nguyen, Thi Lien Anh, Puthanakit, Thanyawee, Silas, Peter, Tangsathapornpong, Auchara, Teeratakulpisarn, Jamaree, Vesikari, Timo, Cohen, Rachel A
Publicado 2022

Protein aggregation and calcium dysregulation are hallmarks of familial Parkinson’s disease in midbrain dopaminergic neurons

por Virdi, Gurvir S., Choi, Minee L., Evans, James R., Yao, Zhi, Athauda, Dilan, Strohbuecker, Stephanie, Nirujogi, Raja S., Wernick, Anna I., Pelegrina-Hidalgo, Noelia, Leighton, Craig, Saleeb, Rebecca S., Kopach, Olga, Alrashidi, Haya, Melandri, Daniela, Perez-Lloret, Jimena, Angelova, Plamena R., Sylantyev, Sergiy, Eaton, Simon, Heales, Simon, Rusakov, Dmitri A., Alessi, Dario R., Kunath, Tilo, Horrocks, Mathew H., Abramov, Andrey Y., Patani, Rickie, Gandhi, Sonia
Publicado 2022

Reduced antibody cross-reactivity following infection with B.1.1.7 than with parental SARS-CoV-2 strains

por Faulkner, Nikhil, Ng, Kevin W, Wu, Mary Y, Harvey, Ruth, Margaritis, Marios, Paraskevopoulou, Stavroula, Houlihan, Catherine, Hussain, Saira, Greco, Maria, Bolland, William, Warchal, Scott, Heaney, Judith, Rickman, Hannah, Spyer, Moria, Frampton, Daniel, Byott, Matthew, de Oliveira, Tulio, Sigal, Alex, Kjaer, Svend, Swanton, Charles, Gandhi, Sonia, Beale, Rupert, Gamblin, Steve J, McCauley, John W, Daniels, Rodney Stuart, Howell, Michael, Bauer, David, Nastouli, Eleni, Kassiotis, George
Publicado 2021

Commercial Immunoglobulin Products Contain Neutralizing Antibodies Against Severe Acute Respiratory Syndrome Coronavirus 2 Spike Protein

por Upasani, Vinit, Townsend, Katie, Wu, Mary Y, Carr, Edward J, Hobbs, Agnieszka, Dowgier, Giulia, Ragno, Martina, Herman, Lou S, Sharma, Sonal, Shah, Devesh, Lee, Simon F K, Chauhan, Neil, Glanville, Julie M, Neave, Lucy, Hanson, Steven, Ravichandran, Sriram, Tynan, Aoife, O’Sullivan, Mary, Moreira, Fernando, Workman, Sarita, Symes, Andrew, Burns, Siobhan O, Tadros, Susan, Hart, Jennifer C L, Beale, Rupert C L, Gandhi, Sonia, Wall, Emma C, McCoy, Laura, Lowe, David M
Publicado 2023

Cytokine release syndrome in a patient with colorectal cancer after vaccination with BNT162b2

por Au, Lewis, Fendler, Annika, Shepherd, Scott T. C., Rzeniewicz, Karolina, Cerrone, Maddalena, Byrne, Fiona, Carlyle, Eleanor, Edmonds, Kim, Del Rosario, Lyra, Shon, John, Haynes, Winston A., Ward, Barry, Shum, Ben, Gordon, William, Gerard, Camille L., Xie, Wenyi, Joharatnam-Hogan, Nalinie, Young, Kate, Pickering, Lisa, Furness, Andrew J. S., Larkin, James, Harvey, Ruth, Kassiotis, George, Gandhi, Sonia, Swanton, Charles, Fribbens, Charlotte, Wilkinson, Katalin A., Wilkinson, Robert J., Lau, David K., Banerjee, Susana, Starling, Naureen, Chau, Ian, Turajlic, Samra
Publicado 2021

Pathological structural conversion of α-synuclein at the mitochondria induces neuronal toxicity

por Choi, Minee L., Chappard, Alexandre, Singh, Bhanu P., Maclachlan, Catherine, Rodrigues, Margarida, Fedotova, Evgeniya I., Berezhnov, Alexey V., De, Suman, Peddie, Christopher J., Athauda, Dilan, Virdi, Gurvir S., Zhang, Weijia, Evans, James R., Wernick, Anna I., Zanjani, Zeinab Shadman, Angelova, Plamena R., Esteras, Noemi, Vinokurov, Andrey Y., Morris, Katie, Jeacock, Kiani, Tosatto, Laura, Little, Daniel, Gissen, Paul, Clarke, David J., Kunath, Tilo, Collinson, Lucy, Klenerman, David, Abramov, Andrey Y., Horrocks, Mathew H., Gandhi, Sonia
Publicado 2022

Author Correction: Pathological structural conversion of α-synuclein at the mitochondria induces neuronal toxicity

por Choi, Minee L., Chappard, Alexandre, Singh, Bhanu P., Maclachlan, Catherine, Rodrigues, Margarida, Fedotova, Evgeniya I., Berezhnov, Alexey V., De, Suman, Peddie, Christopher J., Athauda, Dilan, Virdi, Gurvir S., Zhang, Weijia, Evans, James R., Wernick, Anna I., Zanjani, Zeinab Shadman, Angelova, Plamena R., Esteras, Noemi, Vinokurov, Andrey Y., Morris, Katie, Jeacock, Kiani, Tosatto, Laura, Little, Daniel, Gissen, Paul, Clarke, David J., Kunath, Tilo, Collinson, Lucy, Klenerman, David, Abramov, Andrey Y., Horrocks, Mathew H., Gandhi, Sonia
Publicado 2022