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Mostrando 1 - 20 Resultados de 720 Para Buscar 'Sorvilán~', tiempo de consulta: 7.70s Limitar resultados
  1. 1
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    Editorial: Sortilin and Sortilin Partners in Physiology and Pathologies
  2. 2
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    Sortilin and atherosclerosis
  3. 3
    “…The Panel on Food Additives and Nutrient Sources added to Food (ANS) provides a scientific opinion re‐evaluating the safety of sorbitan monostearate (E 491), sorbitan tristearate (E 492), sorbitan monolaurate (E 493), sorbitan monooleate (E 494) and sorbitan monopalmitate (E 495) when used as food additives. …”
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    Re‐evaluation of sorbitan monostearate (E 491), sorbitan tristearate (E 492), sorbitan monolaurate (E 493), sorbitan monooleate (E 494) and sorbitan monopalmitate (E 495) when used as food additives
  4. 4
    por Lewin, Gary R, Nykjaer, Anders
    Publicado 2014
    “…ProNTs engage a novel receptor system that is distinct from that of mature neurotrophins, consisting of sortilin, a type I membrane protein belonging to the VPS10p family, and its co-receptor, the classic low-affinity neurotrophin receptor p75NTR. …”
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    Pro-neurotrophins, sortilin, and nociception
  5. 5
    “…In this study, we explored the therapeutic potential of sortilin1 (SORT1), a clearance receptor of PGRN, by generating and characterizing monoclonal antibodies against SORT1. …”
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    Anti-sortilin1 Antibody Up-Regulates Progranulin via Sortilin1 Down-Regulation
  6. 6
    por Kandror, Konstantin V.
    Publicado 2017
    “…Sorting receptor, sortilin, is highly expressed in metabolically active tissues, such as brain, liver, skeletal muscle, and fat. …”
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    The role of sortilin in the “Glut4 Pathway”.
  7. 7
    por Strong, Alanna, Rader, Daniel J.
    Publicado 2012
    “…Here we review the identification of the SORT1 locus as a modulator of LDL-C levels and ASCVD risk and the first mechanistic studies that explore the role of Sortilin in lipid metabolism.…”
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    Sortilin as a Regulator of Lipoprotein Metabolism
  8. 8
    “…In light of recent reports suggesting PGRN functions as a protective neurotrophic factor and that sortilin (SORT1) is a neuronal receptor for PGRN, we used a Sort1-deficient (Sort1(−/−)) murine primary hippocampal neuron model to investigate whether PGRN’s neurotrophic effects are dependent on SORT1. …”
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    Progranulin regulates neuronal outgrowth independent of Sortilin
  9. 9
    por Short, Ben
    Publicado 2013
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    Sortilins get a new delivery route
  10. 10
    “…In spite of diverse ligands and also different putative functions of sortilin (NTR3), the function of overexpressed sortilin in ovarian carcinoma cells is an intriguing subject of inquiry. …”
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    The Effect of Sortilin Silencing on Ovarian Carcinoma Cells
  11. 11
    “…Genetic variants in the genomic region containing SORT1 (encoding the protein sortilin) are strongly associated with cholesterol levels and the risk of coronary artery disease (CAD). …”
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    Sortilin as a Biomarker for Cardiovascular Disease Revisited
  12. 12
    “…Here, we report that sortilin and prosaposin independently regulate lysosomal trafficking of progranulin in vivo. …”
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    Regulation of lysosomal trafficking of progranulin by sortilin and prosaposin
  13. 13
    por Liu, Yu, Binks, Bernard P.
    Publicado 2022
    “…[Image: see text] Sorbitan esters have been extensively used as surfactants to stabilize emulsions in many fields. …”
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    Fabrication of Stable Oleofoams with Sorbitan Ester Surfactants
  14. 14
    “…ProNGF-induced apoptosis requires the participation of sortilin as a necessary p75(NTR) co-receptor, suggesting that sortilin may participate in the photoreceptor degeneration triggered by intense lighting. …”
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    Sortilin Participates in Light-dependent Photoreceptor Degeneration in Vivo
  15. 15
    “…We further showed that this PSAP pathway is independent of, but complementary to, the previously identified PGRN lysosomal trafficking mediated by sortilin. Collectively, our results provide new understanding on PGRN trafficking and shed light on the molecular mechanisms behind FTLD and NCL caused by PGRN mutations.…”
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    Prosaposin facilitates sortilin-independent lysosomal trafficking of progranulin
  16. 16
    “…The expression of sortilin is not confined to the nervous system but sortilin is ubiquitously expressed in many tissues. …”
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    A new role under sortilin's belt in cancer
  17. 17
    “…In this study, we examined the role of sortilin in Chlamydia trachomatis L2 development. Western immunoblotting and immunocytochemistry analysis revealed that endogenous sortilin is not only associated with the inclusion, but that protein levels increase in infected cells. …”
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    Sortilin is associated with the chlamydial inclusion and is modulated during infection
  18. 18
    “…Here we demonstrate deposition of fragments from the Vps10p member sortilin at senile plaques (SPs) in aged and AD human cerebrum. …”
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    Sortilin Fragments Deposit at Senile Plaques in Human Cerebrum
  19. 19
    “…Moreover, we found that sortilin-derived propeptide decreased sortilin homodimers within EVs. …”
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    Dimerization of sortilin regulates its trafficking to extracellular vesicles
  20. 20
    “…The multifunctional type 1 receptor sortilin is involved in endocytosis and intracellular transport of ligands. …”
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    PAK Kinases Target Sortilin and Modulate Its Sorting
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