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Mostrando 21 - 40 Resultados de 720 Para Buscar 'Sorvilán~', tiempo de consulta: 4.04s Limitar resultados
  1. 21
    “…Plasma-homocysteine and -sortilin levels were measured with a commercial ELISA kit. …”
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    Sortilin and Homocysteine as Potential Biomarkers for Coronary Artery Diseases
  2. 22
    por Toth, Andrea E., Nielsen, Morten S.
    Publicado 2022
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    Sortilins in the blood-brain barrier: impact on barrier integrity
  3. 23
    “…This study investigated the membrane protein sortilin as a prognosis biomarker for glioblastoma (GBM). …”
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    The Membrane Protein Sortilin Is a Potential Biomarker and Target for Glioblastoma
  4. 24
    “…PURPOSE: To investigate the level and localization of the multifunctional receptor sortilin in the diabetic retina, as well as the effect of sortilin inhibition on retinal neurodegeneration in experimental diabetes. …”
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    Sortilin Inhibition Protects Neurons From Degeneration in the Diabetic Retina
  5. 25
    “…Here we show that AF38469, a small molecule inhibitor of sortilin, improves lysosomal and glial pathology across multiple LSD models. …”
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    Sortilin inhibition treats multiple neurodegenerative lysosomal storage disorders
  6. 26
    “…Recent discoveries demonstrating sortilin (SORT1) is a neuronal receptor for PGRN endocytosis and a determinant of plasma PGRN levels portend the development of enhancers targeting the SORT1–PGRN axis. …”
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    Targeted manipulation of the sortilin–progranulin axis rescues progranulin haploinsufficiency
  7. 27
    “…Here we report that the sorting receptor sortilin plays a key role in cytokine production. We observed interactions of sortilin with multiple cytokines including IFN-α, and sortilin depletion in plasmacytoid dendritic cells (pDCs) led to a reduction of IFN-α secretion, suggesting a pivotal role of sortilin in the exocytic trafficking of IFN-α in pDCs. …”
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    TLR signals posttranscriptionally regulate the cytokine trafficking mediator sortilin
  8. 28
    “…Here, we investigated the role of the proneurotrophin receptor sortilin during phagosome maturation and mycobacterial killing. …”
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    The proneurotrophin receptor sortilin is required for Mycobacterium tuberculosis control by macrophages
  9. 29
    por Venkat, Swati, Linstedt, Adam D.
    Publicado 2017
    “…Thus sortilin-dependent as well as sortilin-independent sorting mechanisms target aggregated Golgi membrane proteins for lysosomal degradation.…”
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    Manganese-induced trafficking and turnover of GPP130 is mediated by sortilin
  10. 30
    “…Sortilin, also known as Neurotensin Receptor-3, and the sorting-related receptor with type-A repeats (SorLA) are both members of the Vps10p domain receptor family. …”
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    Regulatory Roles of Sortilin and SorLA in Immune-Related Processes
  11. 31
    “…The pharmacological properties and physiological roles of the type I receptor sortilin, also called neurotensin receptor-3, are various and complex. …”
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    Sortilin in Glucose Homeostasis: From Accessory Protein to Key Player?
  12. 32
    “…Sortilin is a member of the vacuolar protein sorting 10 protein (VPS10P) domain receptor family, which carries out signal transduction and protein transport in cells. …”
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    Regional and Cellular Mapping of Sortilin Immunoreactivity in Adult Human Brain
  13. 33
    “…PURPOSE: Inflammation is a key contributor to coronary heart disease (CHD). Sortilin is a sorting receptor and has been identified as a critical regulator of inflammatory response. …”
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    The Association Between Sortilin and Inflammation in Patients with Coronary Heart Disease
  14. 34
    “…Among multiple factors which regulate the development of cardiometabolic syndrome, sortilin has been found in multiple cell types, such as adipocyte, hepatocyte, and macrophage, suggesting that sortilin is correlated to the development and the severity of cardiometabolic syndrome. …”
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    Emerging roles of sortilin in affecting the metabolism of glucose and lipid profiles
  15. 35
    “…Sortilin is a post-Golgi trafficking receptor homologous to the yeast vacuolar protein sorting receptor 10 (VPS10). …”
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    Sorting through the extensive and confusing roles of sortilin in metabolic disease
  16. 36
    “…Cellular senescence seems to induce sortilin expression.…”
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    Sortilin Is Upregulated in Osteoarthritis-Dependent Cartilage Calcification and Associated with Cellular Senescence
  17. 37
    “…Here, we report expression of sortilin 1 in ovarian carcinoma tissues both at gene and protein levels. …”
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    Ectopic Expression of Sortilin 1 (NTR-3) in Patients with Ovarian Carcinoma
  18. 38
    “…Sortilin is a member of the family of vacuolar protein sorting 10 protein domain receptors which has emerged as a co-receptor in cell death and neurodegeneration processes mediated by proneurotrophins. …”
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    Dissecting the role of sortilin receptor signaling in neurodegeneration induced by NGF deprivation
  19. 39
    “…The aim of the present study was to widen this focus to sortilin, a receptor involved in neurotrophic signalling. …”
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    Increased serum levels of sortilin are associated with depression and correlated with BDNF and VEGF
  20. 40
    “…In contrast to glucose‐dependent regulation of PGRN gene expression, AMPK activation played a central role in reducing sortilin expression. Overall, the present study suggests that the PGRN–sortilin axis is modulated by glucose deprivation via two distinct mechanisms. …”
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    Glucose deprivation regulates the progranulin–sortilin axis in PC12 cells
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