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  1. 541
    por Beuchot, Mauricio
    Publicado 2018
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    Online Libro
    Interpretación, analogicidad y cultura
  2. 542
    “…Use of massively parallel sequencing and splicing-sensitive junction arrays revealed that levels of 601 mRNAs are changed (including Fus/Tls, progranulin, and other transcripts encoding neurodegenerative disease-associated proteins) and 965 altered splicing events are detected (including in sortilin, the receptor for progranulin), following depletion of TDP-43 from mouse adult brain with antisense oligonucleotides. …”
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    Long pre-mRNA depletion and RNA missplicing contribute to neuronal vulnerability from loss of TDP-43
  3. 543
    “…RESULTS: The nanoemulsion developed by this phase diagram method was composed of 10% rice bran oil, 10% surfactants sorbitan oleate/PEG-30 castor oil, 0.05% antioxidant and 0.50% preservatives formulated in distilled water. …”
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    Formation and stability of oil-in-water nanoemulsions containing rice bran oil: in vitro and in vivo assessments
  4. 544
    “…Recent studies indicated that sortilin-related receptor 1 (SORL1) is a risk gene for late-onset Alzheimer's disease (AD), although its role in the aetiology and/or progression of this disorder is not fully understood. …”
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    An intronic ncRNA-dependent regulation of SORL1 expression affecting Aβ formation is upregulated in post-mortem Alzheimer's disease brain samples
  5. 545
    “…Using a nongaseous monomer, we previously found a simple fabrication method for a free-standing thin film prepared from solution by plasma polymerization, and a nano-suit made by polyoxyethylene (20) sorbitan monolaurate can render multicellular organisms highly tolerant to high vacuum. …”
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    In Situ Preparation of Biomimetic Thin Films and Their Surface-Shielding Effect for Organisms in High Vacuum
  6. 546
    por Kamboj, Sunil, Saini, Vipin, Bala, Suman
    Publicado 2014
    “…Vesicles formulated with sorbitan monostearate were found to have maximum drug release (99.091%) at the end of 24 hours and followed zero order release kinetics. …”
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    Formulation and Characterization of Drug Loaded Nonionic Surfactant Vesicles (Niosomes) for Oral Bioavailability Enhancement
  7. 547
    “…Phylogenetic analysis of the T. thermophila cathepsins, combined with prior work on the role of sortilin receptors in mucocyst biogenesis, suggests that repurposing of lysosomal enzymes was an important step in the evolution of secretory granules in ciliates.…”
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    An aspartyl cathepsin, CTH3, is essential for proprotein processing during secretory granule maturation in Tetrahymena thermophila
  8. 548
    “…The neurotensin (NT) receptor-3 (NTSR3), also called sortilin is a multifunctional protein localized at the intracellular and plasma membrane level. …”
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    Impairement of HT29 Cancer Cells Cohesion by the Soluble Form of Neurotensin Receptor-3
  9. 549
    “…In mammals, this is achieved by neurotrophin (NT) ligands, which promote cell survival via their Trk and p75(NTR) receptors and cell death via p75(NTR) and Sortilin. Drosophila NTs (DNTs) bind Toll receptors instead to promote neuronal survival, but whether they can also regulate cell death is unknown. …”
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    Three-tier regulation of cell number plasticity by neurotrophins and Tolls in Drosophila
  10. 550
    “…Moreover, secreted gelsolin bound to sortilin, which in turn bound to Wiskott-Aldrich syndrome protein family member 3, thereby enhancing the endocytosis and intracellular transport of essential lipids needed to facilitate tumor growth and expansion. …”
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    Secreted gelsolin desensitizes and induces apoptosis of infiltrated lymphocytes in prostate cancer
  11. 551
    “…The prepared MEs were composed of a hydrophilic IL (choline formate, choline lactate, or choline propionate) as the non-aqueous polar phase and a surface-active IL (choline oleate) as the surfactant in combination with sorbitan laurate in a continuous oil phase. The selected ILs were all biologically active ions. …”
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    Ionic Liquid-In-Oil Microemulsions Prepared with Biocompatible Choline Carboxylic Acids for Improving the Transdermal Delivery of a Sparingly Soluble Drug
  12. 552
    “…A non-DIB forming surfactant (sorbitan monooleate, Span 80) was mixed with a lipid (1,2-dioleoyl-sn-glycero-3-phosphocholine, PC), whose adsorption rate on the droplet surface and saturated interfacial tension were lower than those of Span 80. …”
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    Microfluidic Formation of Honeycomb-Patterned Droplets Bounded by Interface Bilayers via Bimodal Molecular Adsorption
  13. 553
    “…RATIONALE: The sortilin-related receptor 1 gene (SORL1) encodes a key protein (SORLA) involved in the pathophysiology of Alzheimer disease (AD). …”
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    SORL1 mutations are associated with parkinsonian and psychiatric features in Alzheimer disease: Case reports
  14. 554
    “…The optimum formulation for the ELM was found at 300 rpm stirring speed, 20 min emulsification time, 3:1 of O/I, 0.1 M ammonia, NH(3) (stripping agent), 6 wt% trioctylamine, TOA (carrier) and 2 wt% sorbitan monooleate, Span 80 (non-ionic surfactant). …”
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    Removal of Ibuprofen at Low Concentration Using a Newly Formulated Emulsion Liquid Membrane
  15. 555
    “…Ritonavir (15% w/w) in a copovidone/sorbitan monolaurate matrix was used as ASD model system. …”
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    Compression of amorphous solid dispersions prepared by hot-melt extrusion, spray drying and vacuum drum drying
  16. 556
    “…In this review, we focus on histopathological biomarkers (particularly CD169 macrophages, neuropilin-1, cofilin-1, interleukin-17, signal transducer and activator of transcription protein 3 (STAT3), LIM domain kinase 1 (LIMK1), CD15, AMACR, prostate-specific membrane antigen (PSMA), Appl1, Sortilin, Syndecan-1, and p63) and their potential application in decision making regarding the prognosis and treatment of PCa patients. …”
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    Novel Histopathological Biomarkers in Prostate Cancer: Implications and Perspectives
  17. 557
    “…The basic composition was enhanced using Sorbitan oleate (E494) and Proviplast as plasticizers, increasing the composite samples’ stability and their mechanical strength. …”
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    Development and Characterization of Polylactic Acid (PLA)-Based Nanocomposites Used for Food Packaging
  18. 558
    “…Moreover, TMED10 also mediates ER export of TGN-localized cargo receptor, sortilin, which subsequently mediates TGN export of IGF2. …”
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    TMED10 mediates the trafficking of insulin-like growth factor 2 along the secretory pathway for myoblast differentiation
  19. 559
    “…Tween 80 is a polyoxyethylene ester of sorbitan monooleate and is liable to enzymatic hydrolysis by lipases. …”
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    THE EFFECT OF WETTING AGENTS ON THE GROWTH OF TUBERCLE BACILLI
  20. 560
    “…While NGF is necessary for BFCN survival and function via binding to the high-affinity receptor TrkA, its uncleaved precursor, pro-NGF has been proposed to induce neurodegeneration via binding to the p75NTR and its coreceptor sortilin. Basal forebrain TrkA and NGF are downregulated with aging while pro-NGF is increased. …”
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    Cholinergic Degeneration and Alterations in the TrkA and p75NTR Balance as a Result of Pro-NGF Injection into Aged Rats
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