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621por Pengon, Sirikarn, Chinatangkul, Nawinda, Limmatvapirat, Chutima, Limmatvapirat, Sontaya“…Coconut oil nanoemulsions containing varied amounts of surfactants including polyethylene glycol octyl phenyl ether (PGO), polyoxyethylene sorbitan monostearate (POS), polyethylene glycol hydrogenated castor oil (PHC), sodium lauryl sulfate (SLS) and poloxamer 407 (PLX) were formulated and comparatively evaluated for their physical properties. …”
Publicado 2018
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622por Elmowafy, Enas, El-Derany, Marwa O., Biondo, Francesca, Tiboni, Mattia, Casettari, Luca, Soliman, Mahmoud E.“…The aim of this study was to prepare nanosized quercetin-loaded niosomes, formulated with different monolaurate sugar esters (i.e., sorbitan C12; glucose C12; trehalose C12; sucrose C12) that act as non-ionic surfactants and with cholesterol as stabilizer (1:1 and 2:1 ratio). …”
Publicado 2020
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623“…We also include two lipoprotein receptors that play essential roles in APP transport: sorting-related receptor with A-type repeats and sortilin. Moreover, we consider here some major disruptions in the neuronal transport of APP that contribute to AD physiology and pathology. …”
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624por Alsabagh, Ahmad Mohamed, Aboulrous, Amany A., Abdelhamid, Mohamed Mahmoud, Mahmoud, Tahany, Haddad, Amin Sharifi, Rafati, Roozbeh“…The mixture of free acids was esterified with sorbitan and then ethoxylated at different ethylene oxide units. …”
Publicado 2021
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625por Xiong, Liu-Lin, Chen, Jie, Du, Ruo-Lan, Liu, Jia, Chen, Yan-Jun, Hawwas, Mohammed Al, Zhou, Xin-Fu, Wang, Ting-Hua, Yang, Si-Jin, Bai, Xue“…The mRNA expression levels of BDNF and its processing enzymes and receptors (Furin, matrix metallopeptidase 9, tissue-type plasminogen activator, tyrosine Kinase receptor B, plasminogen activator inhibitor-1, and Sortilin) were upregulated in the ipsilateral hippocampus and cerebral cortex 6 hours after injury; however, the expression levels of these mRNAs were found to be downregulated in the contralateral hippocampus and cerebral cortex. …”
Publicado 2021
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626por Pomierny, Bartosz, Krzyżanowska, Weronika, Jurczyk, Jakub, Skórkowska, Alicja, Strach, Beata, Szafarz, Małgorzata, Przejczowska-Pomierny, Katarzyna, Torregrossa, Roberta, Whiteman, Matthew, Marcinkowska, Monika, Pera, Joanna, Budziszewska, Bogusława“…Furthermore, AP39 enhanced the pro-survival pathways of neurotrophic factors BDNF-TrkB and NGF-TrkA and reduced the proapoptotic proNGF-p75(NTR)-sortilin pathway activity. These changes corresponded with reduced levels of cleaved caspase 3. …”
Publicado 2021
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627por Guarneri, Fabrizio, Corazza, Monica, Stingeni, Luca, Patruno, Cataldo, Napolitano, Maddalena, Pigatto, Paolo D. M., Gallo, Rosella, Cristaudo, Antonio, Romita, Paolo, Offidani, Annamaria, Schena, Donatella, Milanesi, Nicola, Micali, Giuseppe, Zucca, Myriam, Foti, Caterina“…Positive reactions to both MP and FM1 were observed in 119 subjects (1.0%), 310 (2.6%) reacted to MP only, 304 (2.5%) to FM1 only, 5 to MP and sorbitan sesquioleate (SSO), 9 to FM1 and SSO, and 5 to MP, FM1, and SSO. …”
Publicado 2021
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628“…In the present paper, the interactions between selected cationic, anionic, and nonionic surfactants, namely hexadecylpyridinium chloride (CPC), hexadecyltrimethylammonium bromide (CTAB), sodium dodecyl sulfate (SDS), polyethylene glycol sorbitan monolaurate, monopalmitate, and monooleate (TWEEN 20, TWEEN 40, and TWEEN 80, respectively) with bovine serum albumin (BSA) were studied qualitatively and quantitatively in an aqueous solution (10 mM cacodylate buffer; pH 5.0 and 7.0) by steady-state fluorescence spectroscopy supported by UV spectrophotometry and CD spectroscopy. …”
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629por Sun, Xiaoshuang, Ran, Zongxin, Wu, Yuerong, Zhong, Chengwei, Zhu, Weiwei, Hllah, Hameed, Yu, Jiang“…In this study, three surfactants were used as dispersants to modify nZVI, including poly acrylic (PAA), sorbitan monolaurate (SPAN-20) and sugar esters (SE). …”
Publicado 2022
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630por Taheri-Ledari, Reza, Zolfaghari, Ehsan, Zarei-Shokat, Simindokht, Kashtiaray, Amir, Maleki, Ali“…The surface of nanoparticles was functionalized with sortilin (SORT-1, a human IgG1 monoclonal antibody) that specifically encodes caov-4 ovarian cancerous cells. …”
Publicado 2022
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631por Demeule, Michel, Charfi, Cyndia, Currie, Jean-Christophe, Zgheib, Alain, Danalache, Bogdan Alexandru, Béliveau, Richard, Marsolais, Christian, Annabi, Borhane“…TH1902, a newly developed sortilin (SORT1)-targeted peptide-docetaxel conjugate is currently in phase-1 clinical trial. …”
Publicado 2022
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632por Majumder, Piyali, Edmison, Daisy, Rodger, Catherine, Patel, Sruchi, Reid, Evan, Gowrishankar, Swetha“…In this study, we demonstrate that in human iPSC-derived neurons AP-4 regulates lysosome composition, function, and transport via regulating the export of critical lysosomal receptors, including Sortilin 1, from the trans-Golgi network to endo-lysosomes. …”
Publicado 2022
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633por Peniche, Taires, Duarte, Jonatas L., Ferreira, Ricardo M. A., Sidônio, Igor A. P., Sarquis, Rosângela S. F. R., Sarquis, Ícaro R., Oliveira, Anna E. M. F. M., Cruz, Rodrigo A. S., Ferreira, Irlon M., Florentino, Alexandro C., Carvalho, José C. T., Souto, Raimundo N. P., Fernandes, Caio P.“…The average size diameter of the emulsions (sorbitan monooleate/polysorbate 20) was ≤ 200 nm. The nanoemulsion showed high larvicidal activity in concentrations of 250 and 125 ppm. …”
Publicado 2022
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634por Balanuca, Brindusa, Komartin, Raluca Sanda, Necolau, Madalina Ioana, Damian, Celina Maria, Stan, Raluca“…To avoid the filler sedimentation or its inhomogeneous distribution in the oil matrix, different structure-directing agents (SDA) were employed: 1,3:2,4-dibenzylidene-D-sorbitol (DBS), 12-hydroxystearic acid (HSA) and sorbitan monostearate (Span 60). The SDA and EpLnK effect upon the ELALO-based formulations, their curing reaction and the performance of the resulting materials were investigated. …”
Publicado 2023
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635por Kamran, Muhammad, Laighneach, Aodán, Bibi, Farhana, Donohoe, Gary, Ahmed, Naveed, Rehman, Asim Ur, Morris, Derek W.“…Sortilin-related vacuolar protein sorting 10 (VPS10) domain containing receptor 3 (SORCS3) is a neuron-specific transmembrane protein involved in the trafficking of proteins between intracellular vesicles and the plasma membrane. …”
Publicado 2023
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636por Machado, Francisco Paiva, Folly, Diogo, Esteves, Ricardo, Ruppelt, Bettina Monika, da Silva, Victoria Marques, Matos, Ana Paula dos Santos, dos Santos, José Augusto Albuquerque, Rangel, Leonardo da Silva, Santos, Marcelo Guerra, von Ranke, Natalia Lidmar, Rodrigues, Carlos Rangel, Ricci-Junior, Eduardo, Rocha, Leandro, Faria, Robson Xavier“…The formulation study suggested the F3 formulation as the most promising nanoemulsion with polysorbate 20 and sorbitan monooleate 80 (4:1) with 5% (w/w) essential oil as it showed a smaller droplet size of approximately 100 nm with a PDI lower than 0.3 and prominent bluish reflection. …”
Publicado 2023
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637“…In this manuscript, we introduced a French EOAD patient in Korea who carried the presenilin-1 (PSEN1) Glu318Gly mutations with four possible risk variants, including sortilin-related receptor 1 (SORL1) Glu270Lys, ATP-binding cassette subfamily A member 7 (ABCA7) Val1946Met, translocase of outer mitochondrial membrane 40 (TOMM40) Arg239Trp, and granulin (GRN) Ala505Gly. …”
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638por Kumar-Singh, Samir“…In addition, GRN also interacts with sortilin and is endocytosed, thereby regulating its own levels and possibly also modulating the turnover of other proteins including that of TDP-43. …”
Publicado 2011
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639por Sun, Ying, Lim, Yoon, Li, Fang, Liu, Shen, Lu, Jian-Jun, Haberberger, Rainer, Zhong, Jin-Hua, Zhou, Xin-Fu“…We demonstrated that the receptor proteins for proBDNF, p75NTR and sortilin, were highly expressed in cultured DRG or cortical neurons. …”
Publicado 2012
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640por Siao, Chia-Jen, Lorentz, Christina U., Kermani, Pouneh, Marinic, Tina, Carter, John, McGrath, Kelly, Padow, Victoria A., Mark, Willie, Falcone, Domenick J., Cohen-Gould, Leona, Parrish, Diana C., Habecker, Beth A., Nykjaer, Anders, Ellenson, Lora H., Tessarollo, Lino, Hempstead, Barbara L.“…ProNGF activates p75 neurotrophin receptor (p75(NTR)) and sortilin receptors to mediate proapoptotic responses. …”
Publicado 2012
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