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Mostrando 121 - 140 Resultados de 720 Para Buscar 'Sorvilán~', tiempo de consulta: 4.16s Limitar resultados
  1. 121
    “…In parallel to the increase of BDNF secretion, sortilin, a protein acting as a neurotrophin transporter as well as a co-receptor for p75(NTR), was increased in the cytoplasm of primary and metastatic CRC cells, which suggests that sortilin could regulate neurotrophin transport in these cells. …”
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    Fine-Tuning Roles of Endogenous Brain-Derived Neurotrophic Factor, TrkB and Sortilin in Colorectal Cancer Cell Survival
  2. 122
    “…Although the existence of the soluble form of Sortilin/NTSR3 (sSortilin/NTSR3) has been evidenced for more than 10 years, the studies focusing on the role of this soluble protein at the mechanistic level remain rare. …”
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    Focal Adhesion Kinase-Dependent Role of the Soluble Form of Neurotensin Receptor-3/Sortilin in Colorectal Cancer Cell Dissociation
  3. 123
    “…The silkworm maggot, Exorista sorbillans, is a well-known larval endoparasitoid of the silkworm Bombyx mori that causes considerable damage to the silkworm cocoon crop. …”
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    Comparative Proteomic Analysis Reveals Immune Competence in Hemolymph of Bombyx mori Pupa Parasitized by Silkworm Maggot Exorista sorbillans
  4. 124
    “…PCBP2 recognized the C‐rich element in the 3′ UTR of sortilin mRNA, and PCBP2 knockdown decreased sortilin transcripts, indicating that PCBP2 stabilizes sortilin mRNA by binding to its 3′ UTR. …”
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    PCBP2 post‐transcriptionally regulates sortilin expression by binding to a C‐rich element in its 3′ UTR
  5. 125
    “…This study identifies sortilin-1 as a novel cell factor necessary for the infectivity of a virus; in addition, our results strongly suggest that cathepsins could be common cell factors needed for the infectivity of most rotavirus strains.…”
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    Most rotavirus strains require the cation-independent mannose-6-phosphate receptor, sortilin-1, and cathepsins to enter cells
  6. 126
    “…Co-expression of sortilin and TGFβ in HeLa cells resulted in reduced TGFβ1 secretion. …”
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    Upregulation of Sortilin, a Lysosomal Sorting Receptor, Corresponds with Reduced Bioavailability of Latent TGFβ in Mucolipidosis II Cells
  7. 127
    “…Sortilin is a neuronal receptor for apolipoprotein E (apoE). …”
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    ApoE4 disrupts interaction of sortilin with fatty acid-binding protein 7 essential to promote lipid signaling
  8. 128
    “…Objective  To investigate the CSF levels of sortilin-1, lipocalin-2, autotaxin, decorin, and IL-33 in patients with IIH. …”
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    Cerebrospinal fluid levels of sortilin-1, lipocalin-2, autotaxin, decorin and interleukin-33 in patients with idiopathic intracranial hypertension
  9. 129
    “…SIMPLE SUMMARY: A novel biomarker panel (Appl1, Sortilin and Syndecan-1) was demonstrated as a strong independent predictor for both clinical and biochemical recurrence outcomes, with a higher prediction performance than traditional grading. …”
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    Prediction of Prostate Cancer Biochemical and Clinical Recurrence Is Improved by IHC-Assisted Grading Using Appl1, Sortilin and Syndecan-1
  10. 130
    “…SorLA has been shown to be down regulated in Alzheimer's disease brains, interact with ApoE, and modulate Aβ production. Sortilin has been shown to be part of proNGF mediated death signaling that results from a complex of Sortilin, p75(NTR )and proNGF. …”
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    Sortilin, SorCS1b, and SorLA Vps10p sorting receptors, are novel γ-secretase substrates
  11. 131
    “…TREK-1 and NTSR3/Sortilin were colocalized in mouse cortical neurons. …”
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    Spadin, a Sortilin-Derived Peptide, Targeting Rodent TREK-1 Channels: A New Concept in the Antidepressant Drug Design
  12. 132
    “…In addition, immunofluorescence staining of sortilin and α-synuclein was performed to detect expression in the substantia nigra. …”
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    Long-term adenosine A1 receptor activation-induced sortilin expression promotes α-synuclein upregulation in dopaminergic neurons
  13. 133
    por Marian, Ali J.
    Publicado 2011
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    Genome-Wide Association Studies Complemented with Mechanistic Biological Studies Identify Sortilin 1 as a Novel Regulator of Cholesterol Trafficking
  14. 134
    “…RESULTS: Sortilin levels were significantly increased in individuals with more aggressive PAD (2.25 ± 0.51 ng/mL vs 1.44 ± 0.47 ng/mL, p < 0.001). …”
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    Sortilin levels correlate with major cardiovascular events of diabetic patients with peripheral artery disease following revascularization: a prospective study
  15. 135
    por Cao, Liming, Zhu, Feiqi, Qiu, Guozhen
    Publicado 2020
    “…Early-onset Alzheimer's disease is believed to have a genetic basis, and sporadic Alzheimer's disease has been associated with sortilin-related receptor 1 polymorphism. Case presentation: This report describes and discusses the family report of a 59-year-old patient with early-onset Alzheimer's disease that may have been associated with a sortilin-related receptor 1 gene mutation. …”
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    Early-onset Alzheimer's disease may be associated with sortilin-related receptor 1 gene mutation: A family report and review
  16. 136
    “…As a result, receptor-mediated targeting mechanisms are frequently exploited in conjunction with other drugs and have been the most specific among the group of techniques that have emerged in recent decades. Sortilin (SORT1) is a multifunctional protein whose expression levels have been documented in multiple malignancies, such as ovarian and endometrial tumors. …”
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    The Peptide-Drug Conjugate TH1902: A New Sortilin Receptor-Mediated Cancer Therapeutic against Ovarian and Endometrial Cancers
  17. 137
    “…Principal components analysis revealed a west to east clustering of KORA individuals born in Germany, KORA individuals born in Poland or Czech Republic, Half-Sorbs (less than four Sorbian grandparents) and Full-Sorbs. The Sorbs cluster is nearest to the cluster of KORA individuals born in Poland. …”
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    Population-genetic comparison of the Sorbian isolate population in Germany with the German KORA population using genome-wide SNP arrays
  18. 138
    “…The so-called Polysorbate Sorbitan Phase-Inversion Temperature method has, therefore, been optimized in this experimental work, in order to engineer ultrasmall solid-lipid nanoparticles that were then loaded with α-tocopherol, as the anti-age ingredient for cosmetic application. …”
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    Ultrasmall Solid-Lipid Nanoparticles via the Polysorbate Sorbitan Phase-Inversion Temperature Technique: A Promising Vehicle for Antioxidant Delivery into the Skin
  19. 139
    “…We report that in addition to constitutively spliced full-length sortilin (Sort_FL), we identified an alternatively spliced sortilin variant in human adipocytes. …”
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    FRI027 Regulation Of A Novel Sortilin Splice Variant Expression In Human Diabetic Adipocytes By GLP-1 To Maintain Glucose Homeostasis
  20. 140
    “…Growing evidence has shown that proNGF-p75NTR-sortilin signaling might be a crucial factor in neurodegeneration, but it remains unclear if it may function in nigral neurons under aging and disease. …”
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    Presence of proNGF-Sortilin Signaling Complex in Nigral Dopamine Neurons and Its Variation in Relation to Aging, Lactacystin and 6-OHDA Insults
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