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1441“…The knockdown of fgf22 caused decreased cell proliferation in the midbrain, expanded expression of roof plate and tegmental marker genes, and decreased expression of tectal marker genes, indicating that Fgf22 is required for cell proliferation, roof plate formation, and tectum specification in the midbrain. …”
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1442“…A four-week thermal acclimation of Tegula funebralis to 5, 15, and 25°C did not induce differences in membrane fluidity. …”
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1443por Pinzón-Olejua, Alejandro, Welte, Cornelia, Abdesselem, Houari, Málaga-Trillo, Edward, Stuermer, Claudia AO“…In addition, the retinotectal projection was severely affected in both morphants, as the retina and optic tectum appeared smaller and only few retinal axons reached the abnormally reduced tectal neuropil. The neuronal defects were more persistent in rtn4b morphants. …”
Publicado 2014
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1444por Courjon, Jean-Hubert, Zénon, Alexandre, Clément, Gilles, Urquizar, Christian, Olivier, Etienne, Pélisson, Denis“…This view has been inferred from studies in monkeys showing that some tectal cells located in the deep layers are active prior to reaching movements; it was corroborated by functional imaging studies performed in humans. …”
Publicado 2015
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1445por Sparacia, Gianvincenzo, Anastasi, Andrea, Speciale, Claudia, Agnello, Francesco, Banco, Aurelia“…RESULTS: All patients with Wernicke’s encephalopathy had bilateral areas showing high signal intensity on both T2-weighted and FLAIR MR images in the typical sites (i.e., the periaqueductal region and the tectal plate). Signal intensity abnormalities in the atypical sites (i.e., the cerebellum and the cerebellar vermis) were seen in 4 patients, all of which had no history of alcohol abuse. …”
Publicado 2017
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1446por White, Paul, Saketa, Salanieta, Durand, Alexis, Vaai-Nielsen, Saine, Leong-Lui, Tile Ah, Naseri, Take, Matalima, Ailuai, Amosa, Filipina, Mercier, Alize, Lepers, Christelle, Lal, Vjesh, Wojcik, Richard, Lewis, Sheri, Roth, Adam, Souares, Yvan, Merilles, Onofre Edwin, Hoy, Damian“…The Ministry of Health in Samoa, in partnership with the Pacific Community, successfully implemented enhanced surveillance for the high-profile Third United Nations Conference on Small Island Developing States held concurrently with the popular local Teuila festival during a widespread chikungunya outbreak in September 2014. …”
Publicado 2017
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1447por Pena, Izabella A., Roussel, Yann, Daniel, Kate, Mongeon, Kevin, Johnstone, Devon, Weinschutz Mendes, Hellen, Bosma, Marjolein, Saxena, Vishal, Lepage, Nathalie, Chakraborty, Pranesh, Dyment, David A., van Karnebeek, Clara D. M., Verhoeven-Duif, Nanda, Bui, Tuan Vu, Boycott, Kym M., Ekker, Marc, MacKenzie, Alex“…Epileptiform electrographic activity was observed uniquely in mutants as a series of population bursts in tectal recordings. Remarkably, as is the case in human PDE, the seizures show an almost immediate sensitivity to pyridoxine and pyridoxal 5′-phosphate, with a resulting extension of the life span. …”
Publicado 2017
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1448por Lacalli, Thurston“…Hence, a rudimentary tectal map could have been present before the evolution of image-forming eyes and been coopted by them secondarily. …”
Publicado 2018
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1449por Laghari, Altaf Ali, Baig, Mirza Zain, Bari, Ehsan, Darbar, Aneela, Mushtaq, Naureen, Hani Abdullah, Umm E, Khan, Daniyal Aziz“…There were 16 (88.9%) patients with diffuse intrinsic pontine gliomas (DIPGs), 1 (5.6%) patients with exophytic medullary gliomas, and 1 (5.6%) patient with midbrain/tectal glioma. Mean overall survival (OS) was 9.7 months. …”
Publicado 2019
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1450por Hanna, Joshua A., Mathkour, Mansour, Gouveia, Edna E., Lane, JonMark, Boehm, Lauren, Keen, Joseph R., Biro, Erin E., Sulaiman, Olawale A., Bui, Cuong J.“…Magnetic resonance imaging was significant for a heterogeneous tectal mass, suspicious for a glioma extending to the fourth ventricle and causing displacement of the cerebral aqueduct without obstructive hydrocephalus. …”
Publicado 2020
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1451“…Tumors in the pineal region (13%) were tectal gliomas, germ cell tumors, and pineoblastomas and were mostly treated endoscopically. …”
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1452por Kim, Sung-Eun, Robles-Lopez, Karla, Cao, Xuanye, Liu, Kristyn, Chothani, Pooja J., Bhavani, Nikitha, Rahman, Lauren, Mukhopadhyay, Saikat, Wlodarczyk, Bogdan J., Finnell, Richard H.“…The overall midbrain tissues were expanded and cell proliferation in ventricular zones of midbrain was increased in Gpr161 cKO fetuses, suggesting that protrusive tectal defects in Gpr161 cKO are secondary to the increased proliferation of midbrain neural progenitor cells. …”
Publicado 2021
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1453“…In Wernicke’s encephalopathy, restricted diffusion, T2-FLAIR hyperintensities, and contrast enhancement may be seen in mammillary bodies, dorsomedial thalami, tectal plate, periaqueductal grey matter, and rarely in the cerebellum as well. …”
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1454“…The previous acute respiratory diseases caused by viruses originating from China or the middle east (e.g., SARS, MERS) remained fast developing short diseases without major sequalae or any long-lasting complications. The new COVID-19, on the other hand, not only that it rapidly spread over the world, but some patients never fully recovered or even if they did, a few weeks later started to complain not only of shortness of breath, if any, but general weakness, muscle pains and ‘brain fog’, i.e., fuzzy memories. …”
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1455por Suarez, Milagros, Xiao, Sophie, Abdallah, Aalaa, DuCuypere, Michael, Lam, Sandi, Wadhwani, Nitin, Du, Yuchen, Li, Xiao-Nan“…Moreover, even among brain tumor survivors, many patients are left with long-term cognitive and/or neuroendocrine sequalae. Therefore, more efficacious therapeutic modalities that can improve the patient’s quality of life and increase their survival are urgently needed. 3D organoid cultures have arisen as clinically relevant and molecularly accurate in vitro brain tumor model systems for preclinical drug testing. …”
Publicado 2023
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1456por Diehl, Christian D., Giordano, Frank A., Grosu, Anca-L., Ille, Sebastian, Kahl, Klaus-Henning, Onken, Julia, Rieken, Stefan, Sarria, Gustavo R., Shiban, Ehab, Wagner, Arthur, Beck, Jürgen, Brehmer, Stefanie, Ganslandt, Oliver, Hamed, Motaz, Meyer, Bernhard, Münter, Marc, Raabe, Andreas, Rohde, Veit, Schaller, Karl, Schilling, Daniela, Schneider, Matthias, Sperk, Elena, Thomé, Claudius, Vajkoczy, Peter, Vatter, Hartmut, Combs, Stephanie E.“…Subsequent to disadvantageous cognitive sequalae for the patient and the broad distribution of modern linear accelerators, focal irradiation of the tumor has omitted WBRT in most cases. …”
Publicado 2023
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1457por Wojtecki, Lars, Groiss, Stefan J., Ferrea, Stefano, Elben, Saskia, Hartmann, Christian J., Dunnett, Stephen B., Rosser, Anne, Saft, Carsten, Südmeyer, Martin, Ohmann, Christian, Schnitzler, Alfons, Vesper, Jan“…Eight adverse events and two additional serious adverse events – mostly internal-pallidal stimulation-related – resolved without sequalae. No procedure-related complications occurred. …”
Publicado 2015
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1458“…A better understanding of the neurologic sequalae and radiographic findings will help clinicians mitigate the impact of this disease.…”
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1459por Loree, John T., Burke, Mark S., Rippe, Bridgett, Clarke, Sarah, Moore, Samuel H., Loree, Thom R.“…All complications were addressed without sequalae. Twenty of the 30 (66%) patients have undergone revision surgery. …”
Publicado 2020
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1460por Korompoki, Eleni, Gavriatopoulou, Maria, Hicklen, Rachel S, Ntanasis-Stathopoulos, Ioannis, Kastritis, Efstathios, Fotiou, Despina, Stamatelopoulos, Kimon, Terpos, Evangelos, Kotanidou, Anastasia, Hagberg, Carin A, Dimopoulos, Meletios A, Kontoyiannis, Dimitrios P“…Comparing long COVID with other post viral chronic syndromes may help to contextualize the complex somatic and emotional sequalae of acute COVID-19. The pace of recovery of different aspects of the syndrome remains unclear as the pandemic began only a year ago. …”
Publicado 2021
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