Mostrando 2,061 - 2,080 Resultados de 8,819 Para Buscar 'Telonero~', tiempo de consulta: 3.31s Limitar resultados
  1. 2061
  2. 2062
  3. 2063
  4. 2064
    “…BACKGROUND: Telomere length has been inversely associated with cardiovascular disease in adulthood, but its relationship to preclinical cardiovascular phenotypes across the life course remains unclear. …”
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  5. 2065
  6. 2066
    “…Here, we used CD4 T cells derived from individuals with chronic viral infections or healthy T cells treated with camptothecin (CPT) - a topoisomerase I (Top 1) inhibitor - as a model to investigate the role of DNA topology in reprogramming telomeric DNA damage responses (DDR) and remodeling T cell functions. …”
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  7. 2067
  8. 2068
    “…BACKGROUND: Dyskeratosis congenita (DC) is a rare heritable bone marrow failure syndrome that is associated with telomere dysfunction, and has high genetic heterogeneity and varied features. …”
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  9. 2069
    “…The present study aimed to examine the relationship between leukocyte telomere length (LTL), an index of cellular aging, dispositional mindfulness, and self-compassion in a sample of Singaporean Chinese adults. …”
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  10. 2070
    “…We assessed the association between NS work and DNA methylation of tumor suppressor (TP53, CDKN2A, BRCA1, BRCA2) and estrogen receptor (ESR1, ESR2) genes, methylation of repetitive elements (LINE-1, Alu), and telomere length (TL). Forty six female nurses employed in NS for at least two years were matched by age (30–45 years) and length of service (≥1 year) with 51 female colleagues not working in NS. …”
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  11. 2071
    “…Previous research has indicated that 3D nuclear telomeric and centromeric organization may represent important structural indicators for numerous malignancies. …”
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  12. 2072
    “…In birds, rapid postnatal growth and sudden exposure to aerial oxygen around hatching markedly affect the chick redox status, with potentially negative consequences on physiology mediated by oxidative stress. In addition, telomere length (TL) undergoes reduction during birds’ early life, partly depending on oxidative status. …”
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  13. 2073
  14. 2074
    “…The resulting T/S ratio (telomere to single copy) is proportional to the average telomere length. …”
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  15. 2075
  16. 2076
    “…Background: Activation of telomere maintenance mechanisms (TMMs) is a hallmark of most cancers, and is required to prevent genome instability and to establish cellular immortality through reconstitution of capping of chromosome ends. …”
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  17. 2077
    “…Pulmonary fibrosis and pulmonary arteriovenous malformations are known manifestations of dyskeratosis congenita (DC), a telomere biology disorder (TBD) and inherited bone marrow failure syndrome caused by germline mutations in telomere maintenance genes resulting in very short telomeres. …”
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  18. 2078
    “…Telomere length measured in lymphocytes has been evaluated as a potential biomarker for prostate cancer (PCa) risk. …”
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  19. 2079
  20. 2080
    “…Associations between telomere length and cancer risk have been investigated in many epidemiological studies, but the results are controversial. …”
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