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Mostrando 2,121 - 2,140 Resultados de 8,819 Para Buscar 'Telonero~', tiempo de consulta: 4.66s Limitar resultados
  1. 2121
    por Sławińska, Natalia, Krupa, Renata
    Publicado 2021
    “…DNA damage response (DDR) is triggered by DNA damage or telomere shortening during cell division. When left unresolved, it may lead to the activation of senescence. …”
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    Molecular Aspects of Senescence and Organismal Ageing—DNA Damage Response, Telomeres, Inflammation and Chromatin
  2. 2122
    “…Telomeres are subject to age related shortening which can be accelerated by oxidative stress and inflammation. …”
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    Telomere length as a function of age at population level parallels human survival curves
  3. 2123
    “…Telomeres are organized into a heterochromatin structure and maintenance of silent heterochromatin is required for chromosome stability. …”
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    Metabolic regulation of telomere silencing by SESAME complex-catalyzed H3T11 phosphorylation
  4. 2124
    “…BACKGROUND: Telomeres undergo shortening with each cell division, which could be accelerated by infection. …”
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    Cytomegalovirus Infection and Its Relationship with Leukocyte Telomere Length: A Cross-Sectional Study
  5. 2125
    “…Telomere length is predictive of adult health and survival across vertebrate species. …”
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    Telomere attrition rates are associated with weather conditions and predict productive lifespan in dairy cattle
  6. 2126
    “…BACKGROUND: Short telomere length (TL) is associated with age-related diseases, in particular cardiovascular diseases. …”
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    Telomere Length in Valve Tissue Is Shorter in Individuals With Aortic Stenosis and in Calcified Valve Areas
  7. 2127
    “…The ribonucleoprotein telomerase contains an RNA subunit that serves as the template for the synthesis of telomeric DNA. While telomere elongation is typically primed by a 3′ overhang at existing chromosome ends, telomerase can act upon internal non-telomeric sequences. …”
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    When the Ends Justify the Means: Regulation of Telomere Addition at Double-Strand Breaks in Yeast
  8. 2128
    “…Telomere-binding factor 2 (TRF2) is part of the shelterin protein complex found at chromosome ends. …”
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    The Long Linker Region of Telomere-Binding Protein TRF2 Is Responsible for Interactions with Lamins
  9. 2129
    “…It is well established that short telomeres activate an ATM-driven DNA damage response that leads to senescence in terminally differentiated cells. …”
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    Telomere erosion in human pluripotent stem cells leads to ATR-mediated mitotic catastrophe
  10. 2130
    “…BACKGROUND: Becoming shorter by each cell division, telomere length (TL) is regarded as a marker of cellular aging. …”
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    Telomere length and 8-hydroxy-2-deoxyguanosine as markers for early prediction of Alzheimer disease
  11. 2131
    “…In humans, replication through pericentromeric heterochromatin requires the binding of a complex formed by the telomeric factor TRF2 and the helicase RTEL1 in order to relieve topological barriers blocking fork progression. …”
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    The Telomeric Protein TRF2 Regulates Replication Origin Activity within Pericentromeric Heterochromatin
  12. 2132
    “…Telomere biology disorders are complex clinical conditions that arise due to mutations in genes required for telomere maintenance. …”
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    High-throughput STELA provides a rapid test for the diagnosis of telomere biology disorders
  13. 2133
    por Tucker, Larry A.
    Publicado 2021
    “…The relationship between fruit and vegetable intake and telomere length was examined using a cross-sectional design and an NHANES random sample of 5448 U.S. adults. …”
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    Fruit and Vegetable Intake and Telomere Length in a Random Sample of 5448 U.S. Adults
  14. 2134
    “…OBJECTIVE: Studies of multiple species have found that adverse early life experiences, including childhood trauma and maternal separation, can result in accelerated telomere shortening. The objective of this study was to determine if premature separation from the mother affected telomere length in domestic kittens (Felis catus). …”
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    Early maternal separation is not associated with changes in telomere length in domestic kittens (Felis catus)
  15. 2135
    “…Alternative lengthening of telomeres (ALT) is a telomerase-independent, recombination-based telomere maintenance mechanism that allows cancer cells to acquire unlimited proliferative capacity. …”
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    A C-circle assay for detection of alternative lengthening of telomere activity in FFPE tissue
  16. 2136
    “…Telomere length is regarded as a potential biomarker of biological ageing and is associated with various age-related diseases, such as ischemic heart disease (IHD), myocardial infarction, peripheral vascular disease, and cancer. …”
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    Conventional Risk Factors, Telomere Length, and Ischemic Heart disease: Insights into the Mediation Analysis
  17. 2137
    por Kordowitzki, Paweł
    Publicado 2021
    “…Telomere attrition belongs to the so-called “hallmarks of aging” which are also relevant for the female germ-line cells. …”
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    Oxidative Stress Induces Telomere Dysfunction and Shortening in Human Oocytes of Advanced Age Donors
  18. 2138
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    Clinical diagnostic value of telomere length measurement in inherited bone marrow failure syndromes
  19. 2139
    “…BACKGROUND: Telomere maintenance is crucial for the unlimited proliferation of cancer cells and essential for the “stemness” of multiple cancer cells. …”
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    TAZ maintains telomere length in TNBC cells by mediating Rad51C expression
  20. 2140
    “…Telomeres, highly ordered DNA-protein complexes at eukaryotic linear chromosome ends, are specialized heterochromatin loci conserved among eukaryotes. …”
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    Ccq1–Raf2 interaction mediates CLRC recruitment to establish heterochromatin at telomeres
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