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Mostrando 201 - 220 Resultados de 8,819 Para Buscar 'Telonero~', tiempo de consulta: 3.56s Limitar resultados
  1. 201
    por Zheng, Qian, Huang, Jinliang, Wang, Geng
    Publicado 2019
    “…Mitochondrial functions and telomere functions have mostly been studied independently. …”
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    Mitochondria, Telomeres and Telomerase Subunits
  2. 202
    por Ackermann, Sandra, Fischer, Matthias
    Publicado 2019
    “…Telomere length has been proposed as a biomarker of biological age and a risk factor for age-related diseases and cancer. …”
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    Telomere Maintenance in Pediatric Cancer
  3. 203
    “…Telomere attrition is increased in various disorders and is therefore a potential biomarker for diagnosis and/or prognosis of these disorders. …”
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    Telomere Attrition in Neurodegenerative Disorders
  4. 204
    por Yuan, Xiaotian, Dai, Mingkai, Xu, Dawei
    Publicado 2020
    “…Telomeres are structurally nucleoprotein complexes at termini of linear chromosomes and essential to chromosome stability/integrity. …”
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    Telomere-related Markers for Cancer
  5. 205
    “…At each cell division, telomeres shorten, but the telomerase complex partially counteracts progressive loss of telomeres by catalysing the synthesis of telomeric repeats. …”
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    Telomeres in Interstitial Lung Disease
  6. 206
    “…Over the past decade, telomeres have attracted increasing attention due to the role they play in human fertility. …”
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    Telomere Length and Male Fertility
  7. 207
    “…This review focuses on the current knowledge of the dual role of telomeres in cancer and suggests a new perspective to reconcile the paradox of telomeres and their implications in cancer etiology.…”
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    Telomeres and Cancer: Resolving the Paradox
  8. 208
    “…Telomeres are at the non-coding ends of linear chromosomes. …”
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    Telomeres and Age-Related Diseases
  9. 209
    “…Transgenerational inheritance can occur at telomeres in distinct contexts. Deficiency for telomerase or telomere-binding proteins in germ cells can result in shortened or lengthened chromosome termini that are transmitted to progeny. …”
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    Genetic and Epigenetic Inheritance at Telomeres
  10. 210
    por Alder, Jonathan K., Armanios, Mary
    Publicado 2022
    “…The short telomere defect is pervasive in a subset of IPF patients, and human IPF is the phenotype most intimately tied to germline defects in telomere maintenance. …”
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    Telomere-mediated lung disease
  11. 211
    por Mulet, Alba, Signes-Costa, Jaime
    Publicado 2022
    “…Mutations in telomere-related genes have been identified, but they are not always present despite telomere shortening. …”
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    Idiopathic Pulmonary Fibrosis and Telomeres
  12. 212
    por Yin, Hao, Pickering, J. Geoffrey
    Publicado 2023
    “…PURPOSE OF REVIEW: The purpose of the study is to explore the evidence linking telomere length with atherosclerotic ischemic disease. …”
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    Telomere Length: Implications for Atherogenesis
  13. 213
    “…The end of each chromosome consists of a DNA region termed the telomeres. The telomeres serve as a protective shield against degradation of the coding DNA sequence, as the DNA strand inevitably ‒ with each cell division ‒ is shortened. …”
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    Size matters in telomere biology disorders ‒ expanding phenotypic spectrum in patients with long or short telomeres
  14. 214
    “…Here, we reported a haplotype-resolved and telomere-to-telomere reference genome of M. acuminata by incorporating PacBio HiFi reads, Nanopore ultra-long reads, and Hi-C data. …”
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    The phased telomere-to-telomere reference genome of Musa acuminata, a main contributor to banana cultivars
  15. 215
    “…Alternative lengthening of telomeres (ALT) is a telomere length maintenance mechanism based on recombination, where telomeres use other telomeric DNA as a template for DNA synthesis. …”
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    Telomere elongation involves intra-molecular DNA replication in cells utilizing alternative lengthening of telomeres
  16. 216
    “…We have investigated the role of the telomere-binding Ku complex in specifying late replication of telomere-proximal sequences. …”
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    The effect of Ku on telomere replication time is mediated by telomere length but is independent of histone tail acetylation
  17. 217
    “…Telomere dysregulation occurs in both the in situ and invasive stages of many carcinomas, including breast. …”
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    Coordinate regulation between expression levels of telomere-binding proteins and telomere length in breast carcinomas
  18. 218
    “…The Ccq1 protein, which is known to bind telomere repeats and recruit telomerase, was found to be required to induce H3K9 methylation and thus promote the incorporation of CENP-A(Cnp1) near telomere repeats. …”
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    Telomeric Repeats Facilitate CENP-A(Cnp1) Incorporation via Telomere Binding Proteins
  19. 219
    por Kamranvar, S A, Chen, X, Masucci, M G
    Publicado 2013
    “…Malignant cells achieve replicative immortality by two alternative mechanisms, a common one dependent on de novo synthesis of telomeric DNA by telomerase, and a rare one based on telomere recombination known as alternative lengthening of telomeres (ALT). …”
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    Telomere dysfunction and activation of alternative lengthening of telomeres in B-lymphocytes infected by Epstein–Barr virus
  20. 220
    “…Telomerase, a ribonucleoprotein complex, is responsible for maintaining the telomere length at chromosome ends. Using its RNA component as a template, telomerase uses its reverse transcriptase activity to extend the 3′-end single-stranded, repetitive telomeric DNA sequence. …”
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    Pif1 regulates telomere length by preferentially removing telomerase from long telomere ends
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