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  1. 2181
    “…Telomere length (TL) is associated with biological aging, consequently influencing the risk of age-related diseases such as Alzheimer’s disease (AD). …”
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    Genetically predicted telomere length and Alzheimer’s disease endophenotypes: a Mendelian randomization study
  2. 2182
    “…In a previous study, we observed that leukocyte telomere length (LTL) was strongly correlated with the estimated time to clinical onset in pre-HD subjects. …”
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    Leukocyte Telomere Length as Potential Biomarker of HD Progression: A Follow-Up Study
  3. 2183
    por Sung, Ji-Yong, Cheong, Jae-Ho
    Publicado 2022
    “…Telomere maintenance mechanisms (TMMs) are important for cell survival and homeostasis. …”
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    Single Cell Analysis of Gastric Cancer Reveals Non-Defined Telomere Maintenance Mechanism
  4. 2184
    “…BACKGROUND: Telomerase is a ribonucleoprotein complex consisting of a catalytic component telomerase reverse transcriptase (TERT), internal RNA template and other co‐factors, and its essential function is to synthesize telomeric DNA, repetitive TTAGGG sequences at the termini of linear chromosomes. …”
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    Thyroid carcinoma‐featured telomerase activation and telomere maintenance: Biology and translational/clinical significance
  5. 2185
    “…Both early‐life conditions and growth, and later‐life stressors can create variation in telomere shortening rate. Studies on between‐population telomere length and dynamics are scarce, despite the expectation that populations exposed to varying environmental constraints would present divergent telomere length patterns. …”
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    Population differences in the length and early‐life dynamics of telomeres among European pied flycatchers
  6. 2186
    “…Obesity has negative effects on comorbidities, health-related quality of life and survival. Telomere length (TL) changes after bariatric surgery have been reported, but the studies are contradictory, and analyses using state-of-the art techniques for TL measurement, such as flow-FISH, are sparse. …”
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    Telomere length dynamics measured by flow-FISH in patients with obesity undergoing bariatric surgery
  7. 2187
    “…Cancer cells achieve immortality by employing either homology-directed repair (HDR) or the telomerase enzyme to maintain telomeres. ALT (alternative lengthening of telomeres) refers to the subset of cancer cells that employ HDR. …”
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    TERRA increases at short telomeres in yeast survivors and regulates survivor associated senescence (SAS)
  8. 2188
    “…Telomere dysfunction activates the DNA damage checkpoint to induce a cell cycle arrest. …”
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    The Polo kinase Cdc5 is regulated at multiple levels in the adaptation response to telomere dysfunction
  9. 2189
    “…Telomeric ends form a loop structure (T-loop) necessary for the repression of ATM kinase activation throughout the normal cell cycle. …”
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    A non-catalytic N-terminus domain of WRN prevents mitotic telomere deprotection
  10. 2190
    “…BACKGROUND: The pathogenesis of psoriasis vulgaris involves changes in DNA molecules, genomic instability, telomere attrition, and epigenetic alterations among them. …”
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    Telomere length, oxidative and epigenetic changes in blood DNA of patients with exacerbated psoriasis vulgaris()
  11. 2191
    “…Background: Bladder cancer ranks among the top three in the urology field for both morbidity and mortality. Telomere maintenance-related genes are closely related to the development and progression of bladder cancer, and approximately 60%–80% of mutated telomere maintenance genes can usually be found in patients with bladder cancer. …”
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    Telomere maintenance-related genes are important for survival prediction and subtype identification in bladder cancer
  12. 2192
    “…BACKGROUND: Currently, telomere length is known to reflect the replication potential and longevity of cells, and many studies have reported that telomere length is associated with age-related diseases and biological aging. …”
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    Association between dietary vitamin C and telomere length: A cross-sectional study
  13. 2193
    “…These genes were equally de-repressed in vtc2 ∆ cells and in cells expressing polymerase-dead Vtc4, signifying that polyphosphate synthesis is required for repression of these sub-telomeric genes.…”
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    Inorganic polyphosphate abets silencing of a sub-telomeric gene cluster in fission yeast
  14. 2194
    “…Human herpes virus 6A (HHV-6A) is able to integrate into the telomeric and subtelomeric regions of human chromosomes representing chromosomally integrated HHV-6A (ciHHV-6A). …”
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    The Telomeric Repeats of HHV-6A Do Not Determine the Chromosome into Which the Virus Is Integrated
  15. 2195
    “…Shorter sperm telomeres appear to be associated with altered semen parameters or male infertility. …”
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    Telomere Length, a New Biomarker of Male (in)Fertility? A Systematic Review of the Literature
  16. 2196
    “…Further exploration found that HKSA caused cellular senescence, telomere length shortening, and telomere dysfunction-induced foci (TIF) in limb bones. …”
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    Heat-Killed Staphylococcus aureus Induces Bone Mass Loss through Telomere Erosion
  17. 2197
    “…Although telomerase accounts for the bulk of telomere lengthening methods in human cancer cells, there is a non-negligible portion of telomere lengthening pathways that depend on alternative lengthening of telomeres (ALT) [3]. …”
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    Potential clinical treatment prospects behind the molecular mechanism of alternative lengthening of telomeres (ALT)
  18. 2198
    “…The length of chromosome‐capping telomeres can be used to assess the long‐term costs of parasitism, as telomere loss accelerates in response to environmental stressors and often precedes poorer survival prospects. …”
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    Experimental ectoparasite removal has a sex‐specific effect on nestling telomere length
  19. 2199
    “…BACKGROUND: In cancer cells the three-dimensional (3D) telomere organization of interphase nuclei into a telomeric disk is heavily distorted and aggregates are found. …”
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    3D nuclear organization of telomeres in the Hodgkin cell lines U-HO1 and U-HO1-PTPN1: PTPN1 expression prevents the formation of very short telomeres including "t-stumps"
  20. 2200
    por Inchausti, Daniel
    Publicado 1964
    Materias: “…Terneros Cría y desarrollo…”
    Libro
    Bovinotecnia
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