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  1. 2221
    “…Telomere length (TL) is a marker of biological aging, and shorter telomeres have been associated with several medical and psychiatric disorders, including cardiometabolic dysregulation and Major Depressive Disorder (MDD). …”
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    Shorter telomere length predicts poor antidepressant response and poorer cardiometabolic indices in major depression
  2. 2222
    “…Ovarian aging is the main cause of infertility and telomere attrition is common to both aging and fertility disorders. …”
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    Impaired telomere pathway and fertility in Senescence-Accelerated Mice Prone 8 females with reproductive senescence
  3. 2223
    “…Background and Objectives: Telomeres are repetitive DNA sequences located at the end of chromosomes that play a crucial role in maintaining chromosomal stability. …”
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    Linking Pregnancy and Long-Term Health: The Impact of Cardiovascular Risk on Telomere Shortening in Pregnant Women
  4. 2224
    por Yue, Kun, Yao, Xue
    Publicado 2023
    “…BACKGROUND: This study investigated a potential prognostic model based on telomere-related genes (TRGs) for the clinical prediction of oral squamous cell carcinoma (OSCC). …”
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    Prognostic model based on telomere-related genes predicts the risk of oral squamous cell carcinoma
  5. 2225
    por Han, Xinyu, Wu, Tianqiang, Liu, Chun yan
    Publicado 2023
    “…BACKGROUND: Numerous observational studies have revealed a correlation between telomere length (TL) and adverse pregnancy outcomes (APOs). …”
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    Univariable and multivariable Mendelian randomization investigating the effects of telomere length on the risk of adverse pregnancy outcomes
  6. 2226
    “…Therefore, our objective was to develop a Telomere-TME (TM-TME) classifier that integrates telomere-related genes and immune cell landscape to assess prognosis and therapeutic response in glioma. …”
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    The combined signatures of telomere and immune cell landscape provide a prognostic and therapeutic biomarker in glioma
  7. 2227
    “…Spaceflight elongates human telomeres in peripheral blood, which shorten upon return to Earth and approach baseline levels during postflight recovery. …”
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    Impacts of radiation exposure, hindlimb unloading, and recovery on murine skeletal muscle cell telomere length
  8. 2228
    Publicado 2023
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    Retraction: Leukocyte telomere length and obesity in children and adolescents: a systematic review and meta-analysis
  9. 2229
    “…Telomeres are repetitive DNA sequences at the end of chromosomes that protect them from degradation. …”
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    Low Antioxidant Glutathione Levels Lead to Longer Telomeres: A Sex-Specific Link to Longevity?
  10. 2230
    “…Various harmful influences can contribute to telomere shortening. When telomere length reaches its minimum, the cell dies. …”
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    Association between Combination Antiretroviral Therapy and Telomere Length in People Living with Human Immunodeficiency Virus
  11. 2231
    “…Ataxia telangiectasia mutated (ATM) protein was one of the first DNA damage sensor proteins to be discovered as being involved in DNA repair and as well as in telomere maintenance. Telomeres help maintain the stability of our chromosomes by protecting the ends from degradation. …”
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    Oxidative Damage Induced Telomere Mediated Genomic Instability in Cells from Ataxia Telangiectasia Patients
  12. 2232
    “…Hibernation is linked with various hypotheses to explain the extended lifespan of hibernating mammals compared with their non-hibernating counterparts. Studies on telomeres, markers of ageing and somatic maintenance, suggest telomere shortening slows during hibernation, and lengthening may reflect self-maintenance with favourable conditions. …”
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    Hibernation telomere dynamics in a shifting climate: insights from wild greater horseshoe bats
  13. 2233
    “…Mitochondrial morphology, membrane potential, intracellular reactive oxygen species (ROS), telomerase activity, and telomere length were examined and analyzed accordingly. …”
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    MCCC2 is a novel mediator between mitochondria and telomere and functions as an oncogene in colorectal cancer
  14. 2234
    “…Aim/hypothesis: The relationship between peripheral blood leukocyte telomere length (LTL) and kidney dysfunction, especially in people with hypertension, remains unclear. …”
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    Tumor necrosis factor-alpha mediates the negative association between telomere length and kidney dysfunction
  15. 2235
    “…Aging is considered one of the major risk factors for several human disorders. The telomere plays a crucial role in regulating cellular responsiveness to stress and growth stimuli as well as maintaining the integrity of the Deoxyribonucleic Acid (DNA), and aging leads to the progressive decline in the telomere length (TL) due to continuous cell division. …”
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    Relationship between aging and control of metabolic syndrome with telomere shortening: a cross-sectional study
  16. 2236
    “…Several aspects of telomere biology are regulated by the telomeric repeat-containing RNA TERRA. …”
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    TERRA expression is regulated by the telomere-binding proteins POT-1 and POT-2 in Caenorhabditis elegans
  17. 2237
    “…BACKGROUND: Telomere length (TL) has been regarded as a biomarker of aging, and TL shortening is associated with numerous chronic illnesses. …”
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    Associations of genetically predicted circulating levels of cytokines with telomere length: a Mendelian randomization study
  18. 2238
    “…BACKGROUND: Research on the association between telomere length (TL) and incident non-alcoholic fatty liver disease (NAFLD) is limited. …”
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    The association between telomere length and non-alcoholic fatty liver disease: a prospective study
  19. 2239
    “…Telomeres are conserved chromosomal structures necessary for continued cell division and proliferation. …”
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    Arabidopsis AN3 and OLIGOCELLULA genes link telomere maintenance mechanisms with cell division and expansion control
  20. 2240
    “…In this view, we aimed at discovering molecules able to trigger telomere‐localized DNA damage and tumor cell death. …”
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    Drug repositioning strategy for the identification of novel telomere‐damaging agents: A role for NAMPT inhibitors
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