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Mostrando 2,261 - 2,280 Resultados de 8,819 Para Buscar 'Telonero~', tiempo de consulta: 4.46s Limitar resultados
  1. 2261
    “…Shorter telomeres have been reported in premature myocardial infarction (MI) patients. …”
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    Telomeres are shorter in myocardial infarction patients compared to healthy subjects: correlation with environmental risk factors
  2. 2262
    “…In this study, we determined associations of chromosomal telomere length (TL) to markers of obesity and insulin resistance in middle-aged adult male and female Arabs with and without diabetes mellitus type 2 (DMT2). …”
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    Adiposity and insulin resistance correlate with telomere length in middle-aged Arabs: the influence of circulating adiponectin
  3. 2263
    “…VSG expression is monoallelic such that only one of approximately 15 telomeric VSG expression sites (ESs) is transcribed at a time. …”
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    Histone deacetylases play distinct roles in telomeric VSG expression site silencing in African trypanosomes
  4. 2264
    “…Relative telomere length (T/S) was inversely correlated with cumulative doubling time. …”
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    Telomere Attrition Occurs during Ex Vivo Expansion of Human Dental Pulp Stem Cells
  5. 2265
    “…Intrigued by the dynamics of the seemingly contradictory yet integrated cellular responses to the requisites of preserving telomere integrity while also efficiently repairing damaged DNA, we investigated roles of the telomere associated poly(adenosine diphosphate [ADP]-ribose) polymerase (PARP) tankyrase 1 in both telomere function and the DNA damage response following exposure to ionizing radiation. …”
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    Regulatory roles of tankyrase 1 at telomeres and in DNA repair: suppression of T-SCE and stabilization of DNA-PKcs
  6. 2266
    por Dewar, James M, Lydall, David
    Publicado 2010
    “…Essential telomere ‘capping' proteins act as a safeguard against ageing and cancer by inhibiting the DNA damage response (DDR) and regulating telomerase recruitment, thus distinguishing telomeres from double-strand breaks (DSBs). …”
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    Pif1- and Exo1-dependent nucleases coordinate checkpoint activation following telomere uncapping
  7. 2267
    “…In this study, we show that histones are dynamically acetylated on H4K12 at telomeric heterochromatin, and this acetylation regulates several of the dynamic telomere properties. …”
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    Histone H4 Lysine 12 Acetylation Regulates Telomeric Heterochromatin Plasticity in Saccharomyces cerevisiae
  8. 2268
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    Correction: Zebrafish as a Model System to Study the Physiological Function of Telomeric Protein TPP1
  9. 2269
    “…One aspect of “accelerated aging” in depression may be shortened leukocyte telomeres. When telomeres critically shorten, as often occurs with repeated mitoses or in response to oxidation and inflammation, cells may die. …”
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    Leukocyte Telomere Length in Major Depression: Correlations with Chronicity, Inflammation and Oxidative Stress - Preliminary Findings
  10. 2270
    “…The AC constructs developed from such methods will contain very short telomeric DNA fragments because telomeric repeats can not be stably maintained in Escherichia coli. …”
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    De novo assembly of potential linear artificial chromosome constructs capped with expansive telomeric repeats
  11. 2271
    “…Telomere losses were similar in both groups during the final two years. …”
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    Extended Interferon-Alpha Therapy Accelerates Telomere Length Loss in Human Peripheral Blood T Lymphocytes
  12. 2272
    “…The Ku heterodimer associates with the Saccharomyces cerevisiae telomere, where it impacts several aspects of telomere structure and function. …”
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    Ku Must Load Directly onto the Chromosome End in Order to Mediate Its Telomeric Functions
  13. 2273
    “…BACKGROUND: We aimed to find support for the hypothesis that telomere length (TL) is causally involved in the pathogenesis of ischemic heart failure (IHF). …”
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    Telomere Length of Circulating Leukocyte Subpopulations and Buccal Cells in Patients with Ischemic Heart Failure and Their Offspring
  14. 2274
    “…Interestingly, we observed complex effects of KU70 gene dosage on telomere lengths, with the KU70/ku70 heterozygotes exhibiting slightly shorter telomeres, and the ku70 null strain exhibiting long and heterogeneous telomeres. …”
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    The Candida albicans Ku70 Modulates Telomere Length and Structure by Regulating Both Telomerase and Recombination
  15. 2275
    “…The bone marrow failure syndrome dyskeratosis congenita (DC) has been considered to be a disorder of telomere maintenance in which disease features arise due to accelerated shortening of telomeres. …”
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    Differences in Disease Severity but Similar Telomere Lengths in Genetic Subgroups of Patients with Telomerase and Shelterin Mutations
  16. 2276
    “…We also find that Cdc14 role as a CTD phosphatase is conserved in humans. Finally, telomere segregation defects in cdc14 mutants (4) correlate with the presence of sub-telomeric Y’ elements and can be rescued by transcriptional inhibition of RNA Pol II.…”
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    Cdc14 phosphatase promotes segregation of telomeres through repression of RNA polymerase II transcription
  17. 2277
    “…Telomeres are specialized nucleoprotein structures, which protect chromosome ends and have been implicated in the ageing process. …”
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    Telomeres are favoured targets of a persistent DNA damage response in ageing and stress-induced senescence
  18. 2278
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    Toxoplasma gondii Chromodomain Protein 1 Binds to Heterochromatin and Colocalises with Centromeres and Telomeres at the Nuclear Periphery
  19. 2279
    “…TRF1 and TRF2 are key proteins in human telomeres, which, despite their similarities, have different behaviors upon DNA binding. …”
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    The N-terminal domains of TRF1 and TRF2 regulate their ability to condense telomeric DNA
  20. 2280
    “…Although most of the human telomeric DNA is organized into tightly spaced nucleosomes, their role in telomere protection and how they interplay with telomere-specific factors in telomere organization is still unclear. …”
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    TRF2 Controls Telomeric Nucleosome Organization in a Cell Cycle Phase-Dependent Manner
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