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  1. 2361
    “…Previous work has shown that the three‐dimensional (3D) nuclear organization of telomeres is altered in cancer cells and the degree of alterations coincides with aggressiveness of disease. …”
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    XPO1 Inhibition Preferentially Disrupts the 3D Nuclear Organization of Telomeres in Tumor Cells
  2. 2362
    “…The pattern of guanine oxidation is specific for each telomeric DNA conformation and may serve as an additional tool for probing the G4 topology. …”
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    Light-induced oxidation of the telomeric G4 DNA in complex with Zn(II) tetracarboxymethyl porphyrin
  3. 2363
    “…The molecular mechanisms for this decline are incompletely understood. Although leukocyte telomere length provides an index of cellular age that predicts the incidence of age-related diseases, it is unclear whether there is an association between cognitive decline and leukocyte telomere length. …”
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    Cognitive Change during the Life Course and Leukocyte Telomere Length in Late Middle-Aged Men
  4. 2364
    “…BACKGROUND: Human chromosomes are capped and stabilized by telomeres. Telomere length regulates a ‘cellular mitotic clock’ that defines the number of cell divisions and hence, cellular life span. …”
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    Association between telomere length and the risk of colorectal cancer: a meta-analysis of observational studies
  5. 2365
    “…Human telomerase reverse transcriptase (hTERT) plays a central role in telomere lengthening for continuous cell proliferation, but it remains unclear how extracellular cues regulate telomerase lengthening of telomeres. …”
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    TGF-beta receptor mediated telomerase inhibition, telomere shortening and breast cancer cell senescence
  6. 2366
    “…(TTAGG)(n) - containing telomeres are clearly characteristic of Palpares libelluloides and Acanthaclisis occitanica; the presence of this telomeric motif in Distoleon tetragrammicus is questionable. …”
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    Cytogenetic study on antlions (Neuroptera, Myrmeleontidae): first data on telomere structure and rDNA location
  7. 2367
    “…Telomeres are located at each end of eukaryotic chromosomes. …”
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    Telomere Length Assessment for Prediction of Organ Transplantation Outcome. Future or Failure: A Review of the Literature
  8. 2368
    “…DNA:RNA hybrids, nucleic acid structures with diverse physiological functions, can disrupt genome integrity when dysregulated. Human telomeres were shown to form hybrids with the lncRNA TERRA, yet the formation and distribution of these hybrids among telomeres, their regulation and their cellular effects remain elusive. …”
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    Telomeres in ICF syndrome cells are vulnerable to DNA damage due to elevated DNA:RNA hybrids
  9. 2369
    “…The tumour suppressor gene (Rb1) is necessary for the maintenance of telomere integrity in osteoblastic cells. We now show that the compaction of telomeric chromatin and the appropriate histone modifications of telomeric DNA are both dependent upon Rb1-mediated transcription of the telomere-derived long non-coding RNA TERRA. …”
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    The Rb1 tumour suppressor gene modifies telomeric chromatin architecture by regulating TERRA expression
  10. 2370
    “…Short children born small for gestational age (SGA) are treated with growth hormone (GH), inducing catch-up in length. Leukocyte telomere length (LTL) is a marker of biological age and shorter LTL is associated with increased risk of cardiovascular disease. …”
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    Effects of size at birth, childhood growth patterns and growth hormone treatment on leukocyte telomere length
  11. 2371
    “…OBJECTIVES: To investigate the link between smoking exposure, telomere length and mortality, with emphasis on second-hand smoke (SHS) exposure and the duration of smoking cessation. …”
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    Smoking, second-hand smoke exposure and smoking cessation in relation to leukocyte telomere length and mortality
  12. 2372
    “…PCR-based assay incorporating primers to the telomeric hexamer repeats to polymerize and detect telomeric DNA was used. …”
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    Paired assessment of liver telomere lengths in hepatocellular cancer is a reliable predictor of disease persistence
  13. 2373
    “…Rescue was associated with reduced telomere-dysfunction-induced foci and anaphase bridges, indicating improved telomere capping. …”
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    Mutual reinforcement between telomere capping and canonical Wnt signalling in the intestinal stem cell niche
  14. 2374
    “…We tested the hypothesis that leukocyte telomere length (LTL) is associated with birth weight in both extremes of abnormal fetal growth: small (SGA) and large for gestational age newborns (LGA). …”
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    Telomere length in the two extremes of abnormal fetal growth and the programming effect of maternal arterial hypertension
  15. 2375
    “…Chromosomal aberrations are a hallmark of human cancers, with complex cytogenetic rearrangements leading to genetic changes permissive for cancer initiation and progression. Protection of Telomere 1 (POT1) is an essential component of the shelterin complex and functions to maintain chromosome stability by repressing the activation of aberrant DNA damage and repair responses at telomeres. …”
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    Human Pot1 OB-fold mutations unleash rampant telomere instability to initiate tumorigenesis
  16. 2376
    “…BACKGROUND: The primary aim was to examine possible differences in telomere length between primary health care patients, with depression, anxiety or stress and adjustment disorders, and healthy controls. …”
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    Leukocyte telomere length and depression, anxiety and stress and adjustment disorders in primary health care patients
  17. 2377
    “…Background: It is hypothesized that environmental exposures and behaviour influence telomere length, an indicator of cellular ageing. We systematically associated 461 indicators of environmental exposures, physiology and self-reported behaviour with telomere length in data from the US National Health and Nutrition Examination Survey (NHANES) in 1999–2002. …”
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    Systematic correlation of environmental exposure and physiological and self-reported behaviour factors with leukocyte telomere length
  18. 2378
    “…This study validates and expands on our previous work that assessed three-dimensional (3D) nuclear telomere profiling in buccal cells of Alzheimer’s disease (AD) patients and non-AD controls (Mathur et al., J Alzheimers Dis 39, 35–48, 2014). …”
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    Quantitative 3D Telomeric Imaging of Buccal Cells Reveals Alzheimer’s Disease-Specific Signatures
  19. 2379
    “…Here, we determined the telomere lengths of CD5(+)CD19(+) cells in MBL, CLL, and healthy volunteers. …”
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    Telomere length analysis in monoclonal B-cell lymphocytosis and chronic lymphocytic leukemia Binet A
  20. 2380
    “…Therefore, to understand the inhibition mechanism of hTERT, we studied the binding properties of GO and PGOS with telomere binding protein (AtTRB2). The interaction studies were carried out using circular dichroism, fluorescence, (1)H-(15)N NMR spectroscopy, and size-exclusion chromatography (SEC) binding assay. …”
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    Interaction studies of carbon nanomaterials and plasma activated carbon nanomaterials solution with telomere binding protein
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