Mostrando 261 - 280 Resultados de 8,819 Para Buscar 'Telonero~', tiempo de consulta: 6.87s Limitar resultados
  1. 261
    “…Mammalian Rap1, the most conserved telomere-interacting protein, beyond its role within nucleus for the maintenance of telomeric functions, is also well known for its pleiotropic functions in various physiological and pathological conditions associated with metabolism, inflammation and oxidative stress. …”
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  2. 262
    “…Regulator of telomere length-1 (RTEL1) and telomerase reverse transcriptase (TERT), genes involved in telomere regulation and function, play important roles in maintaining telomere integrity and length. …”
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  3. 263
    “…Approximately 15% of cancers use homologous recombination for alternative lengthening of telomeres (ALT). How the initiating genomic lesions invoke homology-directed telomere synthesis remains enigmatic. …”
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  4. 264
    “…Telomere length (TL) is increasingly being used as a biomarker of senescence, but measuring telomeres remains a challenge. …”
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  5. 265
    “…BACKGROUND: DNA packaging into chromatin regulates all DNA-related processes and at chromosomal ends could affect both essential functions of telomeres: protection against DNA damage response and telomere replication. …”
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  6. 266
  7. 267
    “…Deficiency for telomerase results in transgenerational shortening of telomeres. However, telomeres have no known role in transgenerational epigenetic inheritance. …”
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  8. 268
    “…Each of the other three large scaffolds have telomeres at one end only and we propose that they correspond to sex chromosomes split into a pseudo-autosomal region and X-specific or Y-specific regions. …”
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  9. 269
    por Wang, Lihui, Wang, Zhiguo, Liu, Jun-Ping
    Publicado 2021
    “…Telomere dysfunction-induced focus (TIF) assay allows efficient profiling of telomere dysfunctions in cells and tissues. …”
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  10. 270
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  12. 272
    “…The genome assembly consists of 12 contigs with N50 of 2.86 Mb of which 5 belong to the telomere to telomere (T2T) chromosome. It contains 13.20% repeat sequences, 12,543 proteins, and 12,206 protein-coding genes with the BUSCO completeness 99.18% at fungi (n = 758) and 99.87% at ascomycota (n = 1706), indicating the high accuracy and completeness of our gene annotations. …”
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  13. 273
    por Rubio Aceves, Adriana
    Publicado 1996
    Libro
  14. 274
    Publicado 1975
    Libro
  15. 275
  16. 276
    “…Telomeres are dynamic DNA nucleoprotein structures located at the end of chromosomes where they maintain genomic stability. …”
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  17. 277
  18. 278
    “…Many epidemiologic studies have identified important relationships between leukocyte telomere length (LTL) with genetics and health. Most of these studies have been significantly limited in scope by focusing predominantly on individual diseases or restricted to GWAS analysis. …”
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  19. 279
  20. 280
    “…Here, we summarize the available data and discuss the potential mechanisms of 911 action at telomeres.…”
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