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Mostrando 281 - 300 Resultados de 8,819 Para Buscar 'Telonero~', tiempo de consulta: 4.14s Limitar resultados
  1. 281
    por LeBrasseur, Nicole
    Publicado 2008
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    Stem cells sport longest telomeres
  2. 282
    por Kirwan, Michael, Dokal, Inderjeet
    Publicado 2009
    “…The products of these genes encode components that are critical for telomere maintenance; either because they are core constituents of telomerase (dyskerin, TERC, TERT, NOP10 and NHP2) or are part of the shelterin complex that protects the telomeric end (TIN2). …”
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    Dyskeratosis congenita, stem cells and telomeres
  3. 283
    por Luke, Brian, Lingner, Joachim
    Publicado 2009
    “…Telomeres, the physical ends of eukaryotic chromosomes, consist of tandem arrays of short DNA repeats and a large set of specialized proteins. …”
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    TERRA: telomeric repeat-containing RNA
  4. 284
    “…Due to the “end-replication problem” telomeres shorten with each mitotic cycle resulting in cumulative telomere attrition during aging. …”
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    Telomere biology in healthy aging and disease
  5. 285
    “…Telomere dynamics are intensively studied in human ageing research and epidemiology, with many correlations reported between telomere length and age-related diseases, cancer and death. …”
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    Inheritance of Telomere Length in a Bird
  6. 286
    “…Telomerase is an enzyme that maintains the length of the telomere. The telomere length specifies the number of divisions a cell can undergo before it finally dies (i.e. the proliferative potential of cells). …”
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    Telomere Lengthening and Other Functions of Telomerase

  7. 287
    “…Telomere length in Drosophila is maintained by targeted transposition of three non-LTR retrotransposons: HeT-A, TART and TAHRE (HTT), but understanding the regulation of this process is hindered by our poor knowledge of HTT associated proteins. …”
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    Protein Interactions on Telomeric Retrotransposons in Drosophila
  8. 288
    “…The mechanism by which homologous chromosomes pair during meiosis, as a prelude to recombination, has long been mysterious. At meiosis, the telomeres in many organisms attach to the nuclear envelope and move together to form the telomere bouquet, perhaps to facilitate the homologous search. …”
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    Quantitative Dynamics of Telomere Bouquet Formation
  9. 289
    “…The relationship between telomeres, nevi and melanoma is complex. Shorter telomeres have been found to be associated with many cancers and with number of nevi, a known risk factor for melanoma. …”
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    On the Interplay of Telomeres, Nevi and the Risk of Melanoma
  10. 290
    “…Telomerase is the enzyme responsible for maintenance of the length of telomeres by addition of guanine-rich repetitive sequences. …”
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    Telomere structure and telomerase in health and disease
  11. 291
    por Jacobs, Jacqueline J. L.
    Publicado 2013
    “…Telomeres are repetitive sequences at the natural ends of linear eukaryotic chromosomes that protect these from recognition as chromosome breaks. …”
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    Loss of Telomere Protection: Consequences and Opportunities
  12. 292
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    Telomeric RNA Expression: Length Matters
  13. 293
    por Leslie, Mitch
    Publicado 2013
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    Shelterin protein keeps telomeres on edge
  14. 294
    “…Recent longitudinal studies of age-dependent leukocyte telomere length (LTL) attrition have reported that variable proportions of individuals experience LTL lengthening. …”
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    The telomere lengthening conundrum—artifact or biology?
  15. 295
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    Telomere elongation in parthenogenetic stem cells
  16. 296
    “…Telomere length is considered to be a risk factor in adults due to its proved association with cancer incidence and mortality. …”
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    Genomic Instability in Newborn with Short Telomeres
  17. 297
    “…PSCs generally exhibit high telomerase activity to maintain their extremely long and stable telomeres, and emerging data indicate the alternative lengthening of telomeres (ALT) pathway may play an important role in telomere functions too. …”
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    Telomere regulation in pluripotent stem cells
  18. 298
    “…BACKGROUND: Telomere shortening is a normal age-related process. …”
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    Telomere shortening in leukocyte subpopulations in depression
  19. 299
    por Shibuya, Hiroki, Watanabe, Yoshinori
    Publicado 2014
    “…While the majority of molecular studies have been performed using lower eukaryotes as model systems, recent studies have identified mammalian meiotic telomere regulators, including the LINC-complex SUN1/KASH5 and the meiosis-specific telomere binding protein TERB1. …”
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    The meiosis-specific modification of mammalian telomeres
  20. 300
    por Wang, Caiqin, Zhao, Li, Lu, Shiming
    Publicado 2015
    “…Inappropriate changes in telomere length and/or structure result in telomere dysfunction. …”
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    Role of TERRA in the Regulation of Telomere Length
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