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Mostrando 321 - 340 Resultados de 8,819 Para Buscar 'Telonero~', tiempo de consulta: 6.29s Limitar resultados
  1. 321
    “…Telomere length was determined using high-resolution Single Telomere Length Analysis (STELA). …”
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    Telomere erosion in NF1 tumorigenesis
  2. 322
    por Casacuberta, Elena
    Publicado 2017
    “…Drosophila and extant species are the best-studied telomerase exception. In this organism, telomere elongation is coupled with targeted retrotransposition of Healing Transposon (HeT-A) and Telomere Associated Retrotransposon (TART) with sporadic additions of Telomere Associated and HeT-A Related (TAHRE), all three specialized non-Long Terminal Repeat (non-LTR) retrotransposons. …”
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    Drosophila: Retrotransposons Making up Telomeres
  3. 323
    “…We suggest that these pathways may also influence telomere regulation. Telomere length (TL) attrition may be influenced by obesity-related inflammation and oxidative stress, and FTO gene-involved pathways. …”
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    FTO associations with obesity and telomere length
  4. 324
    “…Telomeres are repetitive tandem DNA sequences that cap chromosomal ends protecting genomic DNA from enzymatic degradation. …”
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    Telomeres, Aging and Exercise: Guilty by Association?
  5. 325
    “…Telomere maintenance and telomere attrition-associated senescence of endothelial and smooth muscle cells have been indicated to be part of the pathogenesis of degenerative vascular diseases. …”
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    Telomere Biology and Thoracic Aortic Aneurysm
  6. 326
    por Hapangama, D.K., Kamal, A., Saretzki, G.
    Publicado 2017
    “…BACKGROUND: Eukaryotic chromosomal ends are linear and are protected by nucleoprotein complexes known as telomeres. The complex structural anatomy and the diverse functions of telomeres as well as the unique reverse transcriptase enzyme, telomerase that maintains telomeres are under intensive scientific scrutiny. …”
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    Implications of telomeres and telomerase in endometrial pathology
  7. 327
    por Savage, Sharon A.
    Publicado 2018
    “…Telomere biology disorders encompass a growing spectrum of conditions caused by rare pathogenic germline variants in genes encoding essential aspects of telomere function. …”
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    Beginning at the ends: telomeres and human disease
  8. 328
    “…Individual chromosome arms have specific individual telomere lengths (TLs). Past studies within species have shown strong positive correlations between individual chromosome length and TL at that chromosome. …”
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    Mammalian chromosome–telomere length dynamics
  9. 329
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    Genetic alterations associated with ALTered telomeres
  10. 330
    “…Telomeres and telomerase have become attractive targets for the development of anticancer therapeutics due to their involvement in cancer cell immortality. …”
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    Oligonucleotides Targeting Telomeres and Telomerase in Cancer
  11. 331
    “…Telomere crisis is linked with many of the genomic alterations found in cancer genomes. …”
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    The ins and outs of telomere crisis in cancer
  12. 332
    “…Mean telomere length in human leukocyte DNA samples reflects the different lengths of telomeres at the ends of the 23 chromosomes and in an admixture of cells. …”
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    The individual’s signature of telomere length distribution
  13. 333
    “…Because leukocyte telomere length is a quantifiable and objectively measurable biomarker of aging, we sought to identify the amount of alcohol consumption associated with the longest telomere length and least telomere length attrition. …”
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    Alcohol consumption and leukocyte telomere length
  14. 334
    por Jezek, Meagan, Green, Erin M.
    Publicado 2019
    “…Telomeres, the nucleoprotein structures at the ends of eukaryotic chromosomes, play an integral role in protecting linear DNA from degradation. …”
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    Histone Modifications and the Maintenance of Telomere Integrity
  15. 335
    “…Telomere and telomerase regulation contributes to the onset and evolution of several tumors, including highly aggressive thyroid cancers (TCs). …”
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    Telomerase and Telomeres Biology in Thyroid Cancer
  16. 336
    “…Telomere dynamics have been found to be better predictors of survival and mortality than chronological age. …”
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    Telomeres and Longevity: A Cause or an Effect?
  17. 337
    “…Recently, reports from three independent laboratories have disclosed a previously unappreciated role for FANCM in telomerase-negative human cancer cells that maintain their telomeres through the Alternative Lengthening of Telomeres (ALT) pathway. …”
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    ALTernative Functions for Human FANCM at Telomeres
  18. 338
    “…The maintenance of telomere length is critical to longevity and survival. …”
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    CtIP is essential for telomere replication
  19. 339
    “…The epigenetic modifications of human telomeres play a relevant role in telomere functions and cell proliferation. …”
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    Assessing the Epigenetic Status of Human Telomeres
  20. 340
    “…Small RNAs with homology to telomeres have been observed in several organisms and could originate from telomeres or from interstitial telomere sequences (ITSs), which are composites of degenerate and perfect telomere repeat sequences found on chromosome arms. …”
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    Telomeric small RNAs in the genus Caenorhabditis
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