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Mostrando 361 - 380 Resultados de 8,819 Para Buscar 'Telonero~', tiempo de consulta: 3.48s Limitar resultados
  1. 361
    “…OBJECTIVES: Short telomeres in alveolar type 2 (AT2) cells have been associated with many lung diseases. …”
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    Telomere shortening impairs alveolar regeneration
  2. 362
    por Yildiz, Ahmet
    Publicado 2022
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    Dynamic folding and accessibility of telomeric overhang
  3. 363
    “…Further understanding of how telomere erosion impairs organ function and how somatic mutations evolve in the hematopoietic tissue may help develop new strategies to treat and prevent telomere diseases.…”
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    Recent advances in understanding telomere diseases
  4. 364
    “…This requires significant proliferative potential ensured by sufficient telomere length. Telomere attrition in the stem cells and their niche cells can result in the exhaustion of the regenerative potential of high-turnover organs, causing or contributing to the onset of age-related diseases. …”
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    Telomeres and Telomerase in the Control of Stem Cells
  5. 365
    “…Telomeres in Drosophila melanogaster, which have inspired a large part of Sergio Pimpinelli work, are similar to those of other eukaryotes in terms of their function. …”
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    Identification of the Telomere elongation Mutation in Drosophila
  6. 366
    “…Therefore, there is considerable interest in studying the epigenetic marks present at relevant chromosomal loci. Telomeric regions, which include telomeres and subtelomeres, have been traditionally considered heterochromatic. …”
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    Epigenetic nature of Arabidopsis thaliana telomeres
  7. 367
    “…Telomeres terminate with a 50–300 bases long single-stranded G-rich overhang, which can be misrecognized as a DNA damage repair site. …”
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    Shelterin reduces the accessibility of telomeric overhangs
  8. 368
    “…In stem and cancer cells, telomeres are actively elongated by either telomerase or the alternative lengthening of telomeres (ALT) pathway. …”
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    Amplification and Quantitation of Telomeric Extrachromosomal Circles
  9. 369
    “…Here, we reported the telomere-to-telomere (T2T) and haplotype-resolved reference genome of ‘Baxijiao’ (Cavendish) consisting of three haploid assemblies. …”
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    Telomere-to-telomere haplotype-resolved reference genome reveals subgenome divergence and disease resistance in triploid Cavendish banana
  10. 370
    “…Telomeres are unique chromatin domains located at the ends of eukaryotic chromosomes. …”
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    Human Sperm Telomere–Binding Complex Involves Histone H2b and Secures Telomere Membrane Attachment
  11. 371
    “…The activation of a telomere maintenance mechanism is required for cancer development in humans. …”
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    Replication protein A prevents accumulation of single-stranded telomeric DNA in cells that use alternative lengthening of telomeres
  12. 372
    “…BACKGROUND: The study of P element repression in Drosophila melanogaster led to the discovery of the telomeric Trans-Silencing Effect (TSE), a homology-dependent repression mechanism by which a P-transgene inserted in subtelomeric heterochromatin (Telomeric Associated Sequences, “TAS”) has the capacity to repress in trans, in the female germline, a homologous P-lacZ transgene located in euchromatin. …”
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    Telomeric Trans-Silencing in Drosophila melanogaster: Tissue Specificity, Development and Functional Interactions between Non-Homologous Telomeres
  13. 373
    “…WRN protein loss causes Werner syndrome (WS), which is characterized by premature aging as well as genomic and telomeric instability. WRN prevents telomere loss, but the telomeric protein complex must regulate WRN activities to prevent aberrant telomere processing. …”
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    Telomeric protein TRF2 protects Holliday junctions with telomeric arms from displacement by the Werner syndrome helicase
  14. 374
    “…BACKGROUND. Leukocyte telomere length (LTL) is considered a biomarker of human aging and based on cross-sectional studies it shortens with age. …”
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    Longitudinal versus Cross-sectional Evaluations of Leukocyte Telomere Length Dynamics: Age-Dependent Telomere Shortening is the Rule
  15. 375
    “…BACKGROUND: To date, the only estimate of the heritability of telomere length in wild populations comes from humans. …”
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    Sex Differences in Sand Lizard Telomere Inheritance: Paternal Epigenetic Effects Increases Telomere Heritability and Offspring Survival
  16. 376
    “…The alternative lengthening of telomeres (ALT) is a recombination-based mechanism of telomere maintenance activated in 5–20% of human cancers. …”
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    Modulation of Telomeres in Alternative Lengthening of Telomeres Type I Like Human Cells by the Expression of Werner Protein and Telomerase
  17. 377
    “…We therefore investigated whether in utero or childhood exposure to NRTIs affects leukocyte telomere length (LTL), a marker of cellular aging. …”
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    Leukocyte Telomere Length in HIV-Infected and HIV-Exposed Uninfected Children: Shorter Telomeres with Uncontrolled HIV Viremia
  18. 378
    “…Telomere length (TL) dynamics in vivo are defined by TL and its age-dependent change, brought about by cell replication. …”
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    Divergence of sperm and leukocyte age-dependent telomere dynamics: implications for male-driven evolution of telomere length in humans
  19. 379
    “…Telomere position effect (TPE) is the influence of telomeres on subtelomeric epigenetic marks and gene expression. …”
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    Telomere length homeostasis and telomere position effect on a linear human artificial chromosome are dictated by the genetic background
  20. 380
    “…[Image: see text] Telomeric repeat-containing RNA (TERRA) is important for telomere regulation, but the structural basis for how TERRA localizes to chromosome ends is unknown. …”
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    An Intramolecular G-Quadruplex Structure Is Required for Binding of Telomeric Repeat-Containing RNA to the Telomeric Protein TRF2
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