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Mostrando 421 - 440 Resultados de 8,819 Para Buscar 'Telonero~', tiempo de consulta: 3.38s Limitar resultados
  1. 421
    por Hodes, Richard J.
    Publicado 1999
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    Telomere Length, Aging, and Somatic Cell Turnover
  2. 422
    por Seimiya, H
    Publicado 2006
    “…The requirement for the maintenance of telomeres by telomerase by most cancer cells for continued proliferation is a target in anticancer strategies. …”
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    The telomeric PARP, tankyrases, as targets for cancer therapy
  3. 423
    por Bibby, M C
    Publicado 1999
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    Telomeres and Telomerase. Ciba Foundation Symposium 211
  4. 424
    “…Telomerase-negative cancer cells maintain their telomeres via the Alternative Lengthening of Telomeres (ALT) pathway1–3. …”
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    Telomere recombination requires the MUS81 endonuclease
  5. 425
    “…Progressive telomere attrition or uncapping of the shelterin complex elicits a DNA damage response (DDR) as a result of a cell’s inability to distinguish dysfunctional telomeric ends from DNA double-strand breaks (DSBs)1. …”
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    Multiple roles for Mre11 at uncapped telomeres
  6. 426
    “…We found that telomere shortening can also be associated with human keloids. …”
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    Telomere shortening may be associated with human keloids
  7. 427
    “…In IPSCs analyzed at passage five (P5), telomeres were significantly elongated in 6/7 lines by >40% and approximated telomere lengths in human embryonic stem cells (hESCs). …”
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    Telomere Dynamics in Human Cells Reprogrammed to Pluripotency
  8. 428
    “…BACKGROUND: Telomere length is a marker of cumulative damage to the cell, and has been associated with cardiovascular disease, hypertension, and diabetes. …”
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    Telomere length, pre-eclampsia, and gestational diabetes
  9. 429
    “…Telomere maintenance is essential to preserve genomic stability and involves several telomere-specific proteins as well as DNA replication and repair proteins. …”
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    ATR contributes to telomere maintenance in human cells
  10. 430
    “…The recent discovery of telomeric RNA transcripts in yeast and vertebrates raised the question of whether RNA–based mechanisms are involved in the formation of telomeric heterochromatin. …”
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    siRNA–Mediated Methylation of Arabidopsis Telomeres
  11. 431
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    Unraveling the roles of WRN and DNA-PKcs at telomeres
  12. 432
    “…Telomere homolog oligonucleotides (T-oligos) activate an innate telomere-based program that leads to multiple anticancer effects. …”
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    Inhibition of Melanoma Angiogenesis by Telomere Homolog Oligonucleotides
  13. 433
    por Yasaei, Hemad, Slijepcevic, Predrag
    Publicado 2010
    “…Two of these proteins, namely Ku and DNA-PKcs, are also involved in maintenance of telomeres, chromosome end-structures. In contrast, cells defective in Ligase IV and XRCC4 do not show changes in telomere length or function suggesting that these proteins are not involved in telomere maintenance. …”
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    Defective Artemis causes mild telomere dysfunction
  14. 434
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    No Correlation Between Childhood Maltreatment and Telomere Length
  15. 435
    “…Telomeres are a hotspot for sister chromatid exchange (T-SCE). …”
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    Telomere sister chromatid exchange and the process of aging
  16. 436
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    Measuring relative telomere length: Is tissue an issue?
  17. 437
    “…Despite the remarkable progress made during the last two decades, our understanding of the biology of aging remains incomplete. Telomere biology has recently emerged as an important player in the aging and disease process.…”
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    Healthy aging and disease: role for telomere biology?
  18. 438
    “…Telomere shortening and telomerase activation occur frequently in cases of colorectal carcinoma. …”
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    Telomere length changes in colorectal cancers and polyps.
  19. 439
    “…Telomere function is influenced by chromatin structure and organization, which usually involves epigenetic modifications. …”
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    Arabidopsis thaliana telomeres exhibit euchromatic features
  20. 440
    por Short, Ben
    Publicado 2011
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    Sir3 helps telomeres stick together
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