Materias dentro de su búsqueda.
Mostrando 441 - 460 Resultados de 8,819 Para Buscar 'Telonero~', tiempo de consulta: 4.96s Limitar resultados
  1. 441
    por Shpiz, Sergey, Kalmykova, Alla
    Publicado 2011
    “…Drosophila telomeres are maintained as a result of transpositions of specialized telomeric retrotransposons. …”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    Role of piRNAs in the Drosophila telomere homeostasis
  2. 442
    por Vera, Elsa, Blasco, Maria A.
    Publicado 2012
    “…The length of telomeres, and in particular the abundance of short telomeres, has been proposed as a biomarker of aging and of general health status. …”
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    Beyond average: potential for measurement of short telomeres
  3. 443
    “…CONCLUSIONS/SIGNIFICANCE: DFT cells appear to monitor and regulate the length of individual telomeres: i.e. shorter telomeres are elongated by up-regulation of telomerase-related genes; longer telomeres are protected from further elongation by members of the shelterin complex, which may explain the lack of spatial and strain variation in DFT telomere copy number. …”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    Telomere Dynamics and Homeostasis in a Transmissible Cancer
  4. 444
    “…The ends of chromosomes in mammals, called telomeres, are composed of a 6-bp repeat sequence, TTAGGG, which is added on by the enzyme telomerase. …”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    Mechanisms of telomere loss and their consequences for chromosome instability
  5. 445
    “…We consider how viral infections modulate telomere regulatory factors for viral repurposing and can alter normal host telomere structure and chromosome stability. …”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    Telomeres and viruses: common themes of genome maintenance
  6. 446
    “…BACKGROUND: Telomeres are essential for the maintenance of genomic stability, and telomere dysfunction leads to cellular senescence, carcinogenesis, aging, and age-related diseases in humans. …”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    Association of telomere instability with senescence of porcine cells
  7. 447
    “…Telomeres are protective chromosomal structures that play a key role in preserving genomic stability. …”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    Drug addiction is associated with leukocyte telomere length
  8. 448
    “…Functional telomeres are critical for stem cell proliferation; however, whether they are equally important for the stability of stem cell differentiation is not known. …”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    Short Telomeres in ESCs Lead to Unstable Differentiation
  9. 449
    “…Telomere length variation has been associated with increased risk of several types of tumors, and telomere shortening, with genetic anticipation in a number of genetic diseases including hereditary cancer syndromes. …”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    Telomere Length and Genetic Anticipation in Lynch Syndrome
  10. 450
    “…Telomeres are the terminal structures at the ends of linear chromosomes that represent a solution to the end replication problem. …”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    Telomeres, A Busy Platform for Cell Signaling
  11. 451
    por Rosen, Eliot M.
    Publicado 2013
    “…We will also describe a recently identified and under-investigated role for BRCA1 in the regulation of telomeres and the implications of this role in the DDR and cancer suppression.…”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    BRCA1 in the DNA damage response and at telomeres
  12. 452
    “…Telomeres protect the chromosome ends from degradation and play crucial roles in cellular aging and disease. …”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    Environmental Stresses Disrupt Telomere Length Homeostasis
  13. 453
    por Watson, J. Matthew, Riha, Karel
    Publicado 2010
    “…Telomeres are essential structures at the ends of eukaryotic chromosomes. …”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    Comparative biology of telomeres: Where plants stand
  14. 454
    “…It has long been established that telomeres and telomere maintenance have a clear role in ageing but it has not yet been established whether there is evidence for adaptation in telomere maintenance proteins that could account for increased longevity in these species. …”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    Molecular adaptation of telomere associated genes in mammals
  15. 455
    “…However, the molecular mechanisms underlying these aging processes remain to be elucidated. As telomere shortening in cultured somatic cells triggers replicative senescence, telomere shortening in oocytes during reproductive and postovulatory aging may predict developmental competence. …”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    Age-associated telomere shortening in mouse oocytes
  16. 456
    por Ishikawa, Fuyuki
    Publicado 2013
    “…Although these processes are seemingly telomere-specific, I will emphasize the possibility that the molecular understanding of the telomere events may shed light on genetic instability at other genetic loci in general.…”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    Portrait of replication stress viewed from telomeres
  17. 457
    “…Telomere length in fetal leucocytes was determined in 82 infants of women with GDM (N = 82) and 65 normal pregnant women (N = 65). …”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    Reduced Fetal Telomere Length in Gestational Diabetes
  18. 458
    “…We recently showed in a cell culture model that DUX4 expression is regulated by telomere length, suggesting that telomere shortening during aging may be partially responsible for the delayed onset and progressive nature of FSHD. …”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    Facioscapulohumeral muscular dystrophy: Are telomeres the end of the story?
  19. 459
    “…Telomeres protect and cap linear chromosome ends, yet these genomic buffers erode over an organism's lifespan. …”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    Telomere Length Reprogramming in Embryos and Stem Cells
  20. 460
    “…In the absence of telomerase, telomeres progressively shorten with every round of DNA replication, leading to replicative senescence. …”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    Length-dependent processing of telomeres in the absence of telomerase
Herramientas de búsqueda: RSS