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Mostrando 521 - 540 Resultados de 8,819 Para Buscar 'Telonero~', tiempo de consulta: 4.02s Limitar resultados
  1. 521
    “…Using three-dimensional (3D) imaging of telomeres, the ends of chromosomes, we report that specific telomeric profiles are associated with aggressive disease. …”
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    Telomere Architecture Correlates with Aggressiveness in Multiple Myeloma
  2. 522
    “…Donor and recipient telomere length have been shown to associate with lung transplant outcomes, including CLAD. …”
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    Airway Telomere Length in Lung Transplant Recipients
  3. 523
    “…Specific proteins present at telomeres ensure chromosome end stability, in large part through unknown mechanisms. …”
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    Mechanism of MRX inhibition by Rif2 at telomeres
  4. 524
    “…Gestational vitamin D intake may prevent several adverse outcomes and might have an influence on offspring telomere length (TL). In this study, we want to assess the association between maternal vitamin D intake during pregnancy and newborn TL, as reflected by cord blood TL. …”
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    Maternal Vitamin D and Newborn Telomere Length
  5. 525
    “…Obesity is a chronic disease, which needs to be early detected early and treated in order prevent its complications. Changes in telomere length (TL) have been associated with obesity and its complications, such as diabetes mellitus and metabolic syndrome. …”
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    Telomere Length and Pediatric Obesity: A Review
  6. 526
    “…Yet, given their length and repetitive nature, telomeric regions are not easily reconstructed from short-read sequencing, thus making telomere sequencing, mapping, and variant resolution challenging problems. …”
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    Haplotype diversity and sequence heterogeneity of human telomeres
  7. 527
    “…To evaluate replicative history and its potential prognostic value, we determined telomere length (TL) in lymphoblasts, B-, and T-lymphocytes, and measured telomerase activity (TA) in leukocytes of patients with ALL. …”
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    Targeting Telomere Biology in Acute Lymphoblastic Leukemia
  8. 528
    “…About 10–15% of all human cancer cells employ a telomerase-independent recombination-based telomere maintenance method, known as alternative lengthening of telomere (ALT), of which the full mechanism remains incompletely understood. …”
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    G-quadruplexes mark alternative lengthening of telomeres
  9. 529
    “…Telomeres form the ends of linear chromosomes and usually comprise protein complexes that bind to simple repeated sequence motifs that are added to the 3′ ends of DNA by the telomerase reverse transcriptase (TERT). …”
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    Telomere Roles in Fungal Genome Evolution and Adaptation
  10. 530
    por Torres-Montaner, A.
    Publicado 2021
    “…Exquisite regulation of telomere length is essential for the preservation of the lifetime function and self-renewal of stem cells. …”
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    The telomere complex and the origin of the cancer stem cell
  11. 531
    “…BACKGROUND: Leukocyte telomere length shortening is a characteristic of premature senescence, a process that can be accelerated by oxidative stress. …”
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    Telomere shortening in patients on long-term hemodialysis
  12. 532
    por Lee, Kyung-Ha, Kim, Do-Yeon, Kim, Wanil
    Publicado 2021
    “…This review provides an overview of the roles of telomere shortening on genomic structural changes during an age-dependent shift in gene expression. …”
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    Regulation of Gene Expression by Telomere Position Effect
  13. 533
    “…Tandem repeats of telomeric-like motifs at intra-chromosomal regions, known as interstitial telomeric repeats (ITR), have drawn attention as potential markers of structural changes, which might convey information about evolutionary relationships if preserved through time. …”
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    Interstitial Arabidopsis-Type Telomeric Repeats in Asteraceae
  14. 534
    “…Furthermore, we report that while telomeric DNA comprises only 0.02–0.07% of the total genome, telomeres contribute between 0.2 and 15% of the total 8-oxoG. …”
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    Quantification of 8-oxoG in Plant Telomeres
  15. 535
    “…In this study, we evaluated the effect of RHPS4, a molecule able to alter telomere by binding to telomeric structures called G-quadruplexes, in patient-derived DDLPS cell lines. …”
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    Telomere as a Therapeutic Target in Dedifferentiated Liposarcoma
  16. 536
    “…We present single-molecule experimental and computational modeling studies investigating the accessibility of human telomeric overhangs of physiologically relevant lengths. …”
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    Emerging accessibility patterns in long telomeric overhangs
  17. 537
    por Aviv, Abraham
    Publicado 2022
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    The telomere tumult: meaning and metrics in population studies
  18. 538
    “…Aims: Aging is accompanied by telomere shortening. Increased telomere shortening is considered a marker of premature aging. …”
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    Common electrocardiogram measures are not associated with telomere length
  19. 539
    “…Telomeres, the natural ends of linear chromosomes, comprise repeat-sequence DNA and associated proteins(1). …”
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    Reconstitution of a telomeric replicon organized by CST
  20. 540
    “…BACKGROUND: Telomere maintenance mechanisms (TMM) are a hallmark of high-risk neuroblastoma, and are conferred by activation of telomerase or alternative lengthening of telomeres (ALT). …”
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    Reliable assessment of telomere maintenance mechanisms in neuroblastoma
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