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Mostrando 641 - 660 Resultados de 8,819 Para Buscar 'Telonero~', tiempo de consulta: 3.01s Limitar resultados
  1. 641
    “…In eukaryotes, the absence of telomerase results in telomere shortening, eventually leading to replicative senescence, an arrested state that prevents further cell divisions. …”
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    The asymmetry of telomere replication contributes to replicative senescence heterogeneity
  2. 642
    por Tawani, Arpita, Kumar, Amit
    Publicado 2015
    “…It interacts with the telomeric sequence through π-stacking at two sites: between T1pT2 and between G6pT7. …”
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    Structural Insight into the interaction of Flavonoids with Human Telomeric Sequence
  3. 643
    “…Background: Telomere length is a putative biomarker of ageing, morbidity and mortality. …”
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    Reproducibility of telomere length assessment: an international collaborative study
  4. 644
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    Radiation Sensitivity and Radiation Necrosis in the Short Telomere Syndromes
  5. 645
    “…Measuring the length distribution of telomeres can reveal information about biological processes that are otherwise difficult to analyze experimentally.…”
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    Telomeres open a window on stem cell division
  6. 646
    por Ivanova, Iglika G., Maringele, Laura
    Publicado 2016
    “…Here, we show that long single-stranded lesions, formed at dysfunctional telomeres in budding yeast, are re-synthesized when cells are removed from the telomere-damaging environment. …”
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    Polymerases ε and ∂ repair dysfunctional telomeres facilitated by salt
  7. 647
    “…Telomeres, as physical ends of linear chromosomes, are targets of a number of specific proteins, including primarily telomerase reverse transcriptase. …”
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    Telomere- and Telomerase-Associated Proteins and Their Functions in the Plant Cell
  8. 648
    “…Long non-coding transcripts from telomeres, called telomeric repeat-containing RNA (TERRA), were identified as blocking telomerase activity (TA), a telomere maintenance mechanism (TMM), in tumors. …”
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    Telomere Transcripts Target Telomerase in Human Cancer Cells
  9. 649
    “…INTRODUCTION: Telomere length, a marker of cell aging, seems to be affected by the same factors thought to be associated with breast cancer prognosis. …”
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    Association of Telomere Length with Breast Cancer Prognostic Factors
  10. 650
    “…Telomeres are responsible for protecting chromosome ends in order to prevent the loss of coding DNA. …”
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    The Role of ATRX in the Alternative Lengthening of Telomeres (ALT) Phenotype
  11. 651
    “…However, a subset of cancer cells lack telomerase activity and rely on the alternative lengthening of telomeres (ALT) pathway, a recombination-based mechanism of telomere elongation. …”
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    SMARCAL1 Resolves Replication Stress at ALT Telomeres
  12. 652
    “…Recent studies have investigated the link between telomeres, the protective cap at the end of chromosomes, and stress, suggesting that stress potentially impacts on cellular aging through telomere shortening, with subsequent consequences for health. …”
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    Telomeres and Stress: Promising Avenues for Research in Psycho-Oncology
  13. 653
    por Sfeir, Agnel, Denchi, Eros Lazzerini
    Publicado 2016
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    Stressed telomeres without POT1 enhance tumorigenesis
  14. 654
    “…The newborn setting of leukocyte telomere length (LTL) likely has important implications for telomere dynamics over the lifespan. …”
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    Impact of Dehydroepiandrosterone Sulfate on Newborn Leukocyte Telomere Length
  15. 655
    “…BACKGROUND: Telomere shortening is thought to be involved in the pathophysiology of myeloid malignancies, but telomere lengths (TL) during interphase and metaphase in hematopoietic malignancies have not been analyzed. …”
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    Dysregulation of Telomere Lengths and Telomerase Activity in Myelodysplastic Syndrome
  16. 656
    por Harari, Yaniv, Kupiec, Martin
    Publicado 2014
    “…Telomeres are specialized DNA-protein structures at the ends of eukaryotic chromosomes. …”
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    Genome-wide studies of telomere biology in budding yeast
  17. 657
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    Corrigendum: Determination of Arabidopsis thaliana telomere length by PCR
  18. 658
    “…Telomeres are essential chromosomal regions that prevent critical shortening of linear chromosomes and genomic instability in eukaryotic cells. …”
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    DNA Replication Origins and Fork Progression at Mammalian Telomeres
  19. 659
    “…Astrocytoma demonstrates two known telomere maintenance mechanisms (TMMs) based on telomerase activity (TA) and on alternative lengthening of telomeres (ALT). …”
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    Epigenetic Regulation of Telomere Maintenance for Therapeutic Interventions in Gliomas
  20. 660
    “…In addition, TRF2 and RAP1 assist recruitment of PRL-3 to telomeric DNA. Silencing of PRL-3 in colon cancer cells does not affect telomere integrity or chromosomal stability, but induces reactive oxygen species-dependent DNA damage response and senescence. …”
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    PRL-3 promotes telomere deprotection and chromosomal instability
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