Mostrando 781 - 800 Resultados de 8,819 Para Buscar 'Telonero~', tiempo de consulta: 5.18s Limitar resultados
  1. 781
  2. 782
    “…Telomere loops (t-loops) are formed at the ends of chromosomes in species ranging from humans to worms, plants, and with genetic manipulation, some yeast. …”
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  3. 783
  4. 784
    “…TEN1 forms a heterotrimeric complex with CTC and STN1, which is essential for telomere protection and maintenance. Telomere length decreases in patients with active HCV, chronic liver disease, and hepatocellular carcinoma. …”
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  5. 785
  6. 786
  7. 787
  8. 788
    “…Defects in telomere maintenance can result in telomere fusions that likely play a causative role in carcinogenesis by promoting genomic instability. …”
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  9. 789
    “…Recently, the influence of telomere length on chromatin organization prior to senescence has revealed the existence of long-distance chromatin loops that dictate the expression of genes located up to 10 Mb from the telomeres (Telomere Position Effect–Over Long Distances [TPE-OLD]). …”
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  10. 790
    “…Next, using the Hierarchical Genome Assembly Process, we assembled the P. falciparum genome de novo and successfully compiled all 14 nuclear chromosomes telomere-to-telomere. We also accurately resolved centromeres [∼90–99% (A + T)] and subtelomeric regions and identified large insertions and duplications that add extra var and rifin genes to the genome, along with smaller structural variants such as homopolymer tract expansions. …”
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  11. 791
    por Daniel, Art, St Heaps, Luke
    Publicado 2004
    “…BACKGROUND: To investigate potential mechanisms for telomere capture the spatial arrangement of telomeres and chromosomes was examined in G1 (non-cycling) mitotic cells with diploid or triploid genomes. …”
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  12. 792
    “…BACKGROUND: Mendelian Randomization (MR) studies exploiting single nucleotide polymorphisms (SNPs) predictive of leukocyte telomere length (LTL) have suggested that shorter genetically determined telomere length (gTL) is associated with increased risks of degenerative diseases, including cardiovascular and Alzheimer’s diseases, while longer gTL is associated with increased cancer risks. …”
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  13. 793
    “…Set1 also promotes proper telomere maintenance, as cells lacking Set1 have short telomeres and disrupted subtelomeric gene repression; however, the precise role for Set1 in these processes has not been fully defined. …”
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  14. 794
    “…In view of the lack of genomic information on bitter gourd and other Momordica species and to promote Mca genomic research, we assembled a 295.6-Mb telomere-to-telomere (T2T) high-quality Mca genome with six gap-free chromosomes after Hi-C correction. …”
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  15. 795
  16. 796
    Libro
  17. 797
    “…Telomerase reverse transcriptase (TERT) is the catalytic subunit of telomerase holoenzyme, which adds telomeric DNA repeats on chromosome ends to counteract telomere shortening. …”
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  18. 798
  19. 799
    “…SIMPLE SUMMARY: This review summarizes the current understanding of the telomere maintenance mechanism known as the Alternative Lengthening of Telomeres (ALT). …”
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  20. 800
    por Zheng, Bo, Fu, Jianhua
    Publicado 2023
    “…Telomere wear and dysfunction may lead to aging-related diseases. …”
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