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Mostrando 801 - 820 Resultados de 8,819 Para Buscar 'Telonero~', tiempo de consulta: 3.62s Limitar resultados
  1. 801
    “…Telomere Biology Disorders (TBDs) are characterized by mutations in telomere-related genes leading to short telomeres and premature aging but with no strict correlation between telomere length and disease severity. …”
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    DNA methylation variations and epigenetic aging in telomere biology disorders
  2. 802
    “…Variability in telomere length is an invaluable parameter in the heterogeneity of the clinical presentation of diseases. …”
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    Association between leukocyte telomere length and COVID-19 severity
  3. 803
    “…Telomeric sequences, the structures comprised of hexanucleotide repeats and associated proteins, play a pivotal role in chromosome end protection and preservation of genomic stability. …”
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    The dynamics of telomere length in primary and metastatic colorectal cancer lesions
  4. 804
    “…Here we test whether these mitigation measures also affect the rate of cellular ageing of the fish, measured in terms of the telomeres that cap the ends of eukaryotic chromosomes. …”
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    Habitat restoration weakens negative environmental effects on telomere dynamics
  5. 805
    “…Telomeres, also known as the “protective caps” of our chromosomes, shorten with each cell cycle due to the end replication problem. …”
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    Exploring the Causal Relationship Between Telomere Biology and Alzheimer’s Disease
  6. 806
    “…The telomere length of human blastocysts exceeds that of oocytes and telomerase activity increases after zygotic activation, peaking at the blastocyst stage. …”
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    The Landscape of Telomere Length and Telomerase in Human Embryos at Blastocyst Stage
  7. 807
    “…Human telomeres are linked to genetic instability and a higher risk of developing cancer. …”
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    Telomere-related prognostic biomarkers for survival assessments in pancreatic cancer
  8. 808
    “…Telomeres are tandem repeats of DNA sequences protecting the end of linear chromosomes. …”
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    An overview of the role of telomeres and telomerase in pre‑neoplastic lesions (Review)
  9. 809
    “…Telomere maintenance is a hallmark of malignant cells and allows cancers to divide indefinitely. …”
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    Induction of the alternative lengthening of telomeres pathway by trapping of proteins on DNA
  10. 810
    “…Our results suggest that klotho levels and telomere length may be associated through a coordinated downregulation of longevity factors occurring under higher stress caregiving conditions.…”
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    Associations between klotho and telomere biology in high stress caregivers
  11. 811
    por Cai, Sarah W., de Lange, Titia
    Publicado 2023
    “…It has been known for decades that telomerase extends the 3′ end of linear eukaryotic chromosomes and dictates the telomeric repeat sequence based on the template in its RNA. …”
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    CST–Polα/Primase: the second telomere maintenance machine
  12. 812
    “…Telomeric repeat-containing RNA (TERRA) is a class of long noncoding RNAs (lncRNAs) that are transcribed from subtelomeric to telomeric region of chromosome ends. …”
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    RBMX involves in telomere stability maintenance by regulating TERRA expression
  13. 813
    “…The shortest median telomere lengths were detected among subsets that lacked expression of CD45RA, and the longest median telomere lengths were detected among subsets that expressed CD45RA. …”
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    T cell memory revisited using single telomere length analysis
  14. 814
    “…The aim of this systematic review is to evaluate telomere dynamics throughout pregnancy and the association between parity and TL. …”
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    Are pregnancy and parity associated with telomere length? A systematic review
  15. 815
    por Fernández-Álvarez, Alfonso
    Publicado 2023
    “…The telomere bouquet is a specific chromosomal configuration that forms during meiosis at the zygotene stage, when telomeres cluster together at the nuclear envelope. …”
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    Beyond tradition: exploring the non-canonical functions of telomeres in meiosis
  16. 816
    “…TERRA (telomeric repeat-containing RNA) is a class of long noncoding RNAs transcribed from subtelomeric and telomeric regions. …”
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    Telomeric repeat-containing RNA is dysregulated in acute myeloid leukemia
  17. 817
    “…Analysis of terminal deletion chromosomes indicates that a sequence-independent mechanism regulates protection of Drosophila telomeres. Mutations in Drosophila DNA damage response genes such as atm/tefu, mre11, or rad50 disrupt telomere protection and localization of the telomere-associated proteins HP1 and HOAP, suggesting that recognition of chromosome ends contributes to telomere protection. …”
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    Epigenetic Telomere Protection by Drosophila DNA Damage Response Pathways
  18. 818
    “…We constructed mutants missing each of the protein subunit of telomerase and analyzed overall telomere dynamics and single-stranded telomere overhangs over the course of many generations. …”
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    Modulation of telomere terminal structure by telomerase components in Candida albicans
  19. 819
    “…G-quadruplex structures inhibit telomerase activity and must be disrupted for telomere elongation during S phase. It has been suggested that the replication protein A (RPA) could unwind and maintain single-stranded DNA in a state amenable to the binding of telomeric components. …”
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    Human replication protein A unfolds telomeric G-quadruplexes
  20. 820
    por Casacuberta, Elena, Pardue, Mary-Lou
    Publicado 2006
    “…Unlike many other organisms, Drosophila maintains its telomeres by the transposition of retrotransposons to chromosome ends. …”
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    RNA interference has a role in regulating Drosophila telomeres
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