Mostrando 841 - 860 Resultados de 8,819 Para Buscar 'Telonero~', tiempo de consulta: 5.89s Limitar resultados
  1. 841
    “…METHODS: Mammary tumor cells were treated by a 16-base phosphodiester-linked oligonucleotide homologous to the telomere G-rich sequence TTAGGG (T-oligo: GGTTAGGTGTAGGTTT) or a control-oligo (the partial complement, TAACCCTAACCCTAAC) followed by IR. …”
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  2. 842
  3. 843
    “…Heterogeneity in telomere length within oocytes may provide an opportunity to improve the treatment of infertility through telomere-based selection of oocytes and embryos with reproductive competence.…”
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  4. 844
    “…There is increasing evidence suggesting that short telomeres and subsequent genomic instability contribute to malignant transformation. …”
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  5. 845
    “…In the Drosophila germline, retrotransposons are silenced by the PIWI-interacting RNA (piRNA) pathway. Telomeric retroelements HeT-A, TART and TAHRE, which are involved in telomere maintenance in Drosophila, are also the targets of piRNA-mediated silencing. …”
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  6. 846
  7. 847
    “…BACKGROUND: In Saccharomyces cerevisiae genes that are located close to a telomere can become transcriptionally repressed by an epigenetic process known as telomere position effect. …”
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  8. 848
    “…Replicative senescence is accompanied by a telomere-specific DNA damage response (DDR). We found that DDR+ telomeres occur spontaneously in early-passage normal human cells and increase in number with increasing cumulative cell divisions. …”
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  9. 849
  10. 850
    “…Telomeres are regions of repetitive DNA at the end of eukaryotic chromosomes, which prevent chromosomal instability. …”
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  11. 851
  12. 852
    “…Telomeres, which form the protective ends of eukaryotic chromosomes, are a ubiquitous and conserved structure of eukaryotic genomes but the basic structural unit of most telomeres, a repeated minisatellite motif with the general consensus sequence T(n)A(m)G(o), may vary between eukaryotic groups. …”
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  13. 853
    “…Through the use of circular dichroism, UV-visible spectroscopy and fluorescence resonance energy transfer (FRET) melting assay we have shown that NMM stabilizes human telomeric DNA dAG(3)(TTAG(3))(3) (Tel22) and is selective for its parallel conformation to which it binds in 1:1 stoichiometry with a binding constant of ∼1.0 × 10(5) M(−1). …”
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  14. 854
  15. 855
  16. 856
    “…Telomere maintenance and DNA repair are important processes that protect the genome against instability. mRtel1, an essential helicase, is a dominant factor setting telomere length in mice. …”
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  17. 857
    “…This paper will explore the areas where telomere and telomerase biology can have significant effects on various tissues in the body in IUGR outcomes.…”
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  18. 858
    “…The DNA at the ends of linear chromosomes (the telomere) folds back onto itself and forms an intramolecular lariat-like structure. …”
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  19. 859
    “…We thus found no significant relationship between change in telomere length and age. However, telomeres tended to shorten at a faster pace in juveniles compared to adults. …”
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  20. 860
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