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Mostrando 941 - 960 Resultados de 8,819 Para Buscar 'Telonero~', tiempo de consulta: 4.91s Limitar resultados
  1. 941
    “…All tumors have in common to reactivate a telomere maintenance mechanism to allow for unlimited proliferation. …”
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    Measurement of Telomere Length in Colorectal Cancers for Improved Molecular Diagnosis
  2. 942
    “…Both leukocyte telomere length (LTL) and DNA methylation age are strongly associated with chronological age. …”
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    Leukocyte telomere length, T cell composition and DNA methylation age
  3. 943
    “…Telomeres and the insulin/PI3K pathway are considered hallmarks of aging and cancer. …”
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    Modulation of telomere protection by the PI3K/AKT pathway
  4. 944
    “…In the present communication, we have discussed the usefulness of shortening of telomeres as a potential biomarker of CAD. Clinical research evidence in favour of telomere shortening in CAD is well documented in different ethnic populations of the world. …”
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    Telomere length as a potential biomarker of coronary artery disease
  5. 945
    “…Improved methods to measure the shortest (not just average) telomere lengths (TLs) are needed. We developed Telomere Shortest Length Assay (TeSLA), a technique that detects telomeres from all chromosome ends from <1 kb to 18 kb using small amounts of input DNA. …”
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    A method for measuring the distribution of the shortest telomeres in cells and tissues
  6. 946
    “…This suggests that early life is an important period in the determination of telomere length. We investigated the importance of the early-life environment on both telomere tracking and adult telomere length. …”
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    Telomere tracking from birth to adulthood and residential traffic exposure
  7. 947
    “…Leukocyte telomere length (TL) has been suggested as a marker of biological age in healthy individuals, but can also reflect inherited and acquired hematopoietic dysfunctions or indicate an increased turnover of the hematopoietic stem and progenitor cell compartment. …”
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    Telomeres and Telomerase in Hematopoietic Dysfunction: Prognostic Implications and Pharmacological Interventions
  8. 948
    “…Tethering telomeres to the inner nuclear membrane (INM) allows for homologous chromosome pairing during meiosis. …”
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    Dissecting the telomere-inner nuclear membrane interface formed in meiosis
  9. 949
    “…Besides controlling epithelial-to-mesenchymal transition (EMT) and cell invasion, the Snail1 transcriptional factor also provides cells with cancer stem cell features. Since telomere maintenance is essential for stemness, we have examined the control of telomere integrity by Snail1. …”
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    Snail1 transcription factor controls telomere transcription and integrity
  10. 950
    Publicado 2018
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    Erratum: Telomeres and Stress: Promising Avenues for Research in Psycho-Oncology
  11. 951
    “…Analysis of telomere lengths and telomeric gene silencing in strains containing different combinations of cdc73Δ, tel1Δ and yku80Δ mutations suggested that combinations of these mutations caused increased defects in telomere maintenance. …”
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    Cdc73 suppresses genome instability by mediating telomere homeostasis
  12. 952
    “…Telomere maintenance critically depends on the distinct activities of telomerase, which adds telomeric repeats to solve the end replication problem, and RTEL1, which dismantles DNA secondary structures at telomeres to facilitate replisome progression. …”
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    Stabilization of Reversed Replication Forks by Telomerase Drives Telomere Catastrophe
  13. 953
    por Cestari, Igor, Stuart, Ken
    Publicado 2018
    “…VSG antigenic switching occurs by transcriptional switching between telomeric ESs or by recombination of the VSG gene expressed. …”
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    Transcriptional Regulation of Telomeric Expression Sites and Antigenic Variation in Trypanosomes
  14. 954
    por Tardat, Mathieu, Déjardin, Jérôme
    Publicado 2017
    “…Telomeres are specialized structures that evolved to protect the end of linear chromosomes from the action of the cell DNA damage machinery. …”
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    Telomere chromatin establishment and its maintenance during mammalian development
  15. 955
    “…PURPOSE: Telomere length is a biomarker of cellular ageing, with longer telomeres associated with longevity and reduced risk of chronic disease in older age. …”
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    Diet quality and telomere length in older Australian men and women
  16. 956
    “…The length of telomere restriction fragments (TRF) was studied by Southern blotting in 42 patients with acute myelocytic leukemia (AML) including 15 patients with 8;21 translocation, 8 with 15;17 translocation and 19 with a normal karyotype. …”
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    Telomere Reduction of Specific Chromosome Translocation in Acute Myelocytic Leukemia
  17. 957
    “…The function of the yeast (Saccharomyces cerevisiae) ortholog of GOLPH3, Vps74, in the DNA damage response has been little studied, although genome-wide screens suggested a role at telomeres. In this study we investigated the role of Vps74 at telomeres and in the DNA damage response. …”
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    Vps74 Connects the Golgi Apparatus and Telomeres in Saccharomyces cerevisiae
  18. 958
    “…Telomeres maintain the integrity of chromosome ends and telomere length is an important marker of aging. …”
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    ATF7 mediates TNF-α–induced telomere shortening
  19. 959
    “…Upon telomerase inactivation, telomeres gradually shorten with each cell division until cells enter replicative senescence. …”
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    Histone depletion prevents telomere fusions in pre-senescent cells
  20. 960
    “…METHODS: Relative telomere length (RTL) was measured with a Q-PCR based method in 3,316 participants of the LURIC study. …”
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    Telomere length and mortality in the Ludwigshafen Risk and Cardiovascular Health study
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