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Mostrando 1,081 - 1,100 Resultados de 8,819 Para Buscar 'Telonero~', tiempo de consulta: 5.32s Limitar resultados
  1. 1081
    “…This study aimed to explore the role of telomere length in three different diabetes types: latent autoimmune diabetes of adulthood (LADA), latent autoimmune diabetes in the young (LADY), and type 2 diabetes mellitus (T2DM). …”
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    Telomere Shortening in Three Diabetes Mellitus Types in a Mexican Sample
  2. 1082
    “…Telomeres and telomerase are closely linked to uncontrolled cellular proliferation, immortalization and carcinogenesis. …”
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    The Relevance of Telomerase and Telomere-Associated Proteins in B-Acute Lymphoblastic Leukemia
  3. 1083
    “…Leukocyte telomere length (LTL) gets shorter with each cell division and is also sensitive to reactive oxygen species damage and inflammatory processes. …”
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    Shorter leukocyte telomere length protects against NAFLD progression in children
  4. 1084
    “…Alternative lengthening of telomeres (ALT) supports telomere maintenance in 10–15% of cancers, thus representing a compelling target for therapy. …”
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    Signalling inhibition by ponatinib disrupts productive alternative lengthening of telomeres (ALT)
  5. 1085
    “…A plethora of intrinsic and environmental factors have been shown to influence the length of telomeres, the protector of chromosome ends. Despite the growing interest in infection–telomere interactions, there is very limited knowledge on how transmissible cancers influence telomere maintenance. …”
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    Transmissible cancer and longitudinal telomere dynamics in Tasmanian devils (Sarcophilus harrisii)
  6. 1086
    “…OBJECTIVE: Previous research has shown a significant association between weight and telomere length, but did not take into consideration weight range. …”
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    Association of weight range with telomere length: A retrospective cohort study
  7. 1087
    “…The underlying mechanisms of plasma metabolite signatures of human aging and age-related diseases are not clear but telomere attrition and dysfunction are central to both. …”
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    Dyskeratosis Congenita Links Telomere Attrition to 
Age-Related Systemic Energetics
  8. 1088
    “…The G-rich DNA sequence at telomeres has a propensity to form G4s of various topologies. …”
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    RPA engages telomeric G-quadruplexes more effectively than CST
  9. 1089
    “…Telomere length (TL) is a well-known marker of age-related diseases. …”
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    Lipoprotein Particle Profiles Associated with Telomere Length and Telomerase Complex Components
  10. 1090
    “…Telomere length (TL) limits somatic cell replication. …”
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    Buildup from birth onward of short telomeres in human hematopoietic cells
  11. 1091
    “…During tumor development, cells achieve immortality by activating telomere maintenance mechanisms. Alternative lengthening of telomere (ALT) is an important mechanism for maintaining telomere length and cell proliferation in tumor cells. …”
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    Alternative Lengthening of Telomeres in Pediatric High-Grade Glioma and Therapeutic Implications
  12. 1092
    “…Racism is a determinant of individual and offspring health. Accelerated telomere shortening, an indicator of cellular aging, is a potential mechanism through which parental experience of racism could affect offspring. …”
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    Maternal racism experience and cultural identity in relation to offspring telomere length
  13. 1093
    “…The piRNAs most transcriptionally affected by NSL2 and NSL1 RNAi map to telomeric piRNA clusters. At the chromatin level, these piRNA clusters also show decreased levels of H3K9me3, HP1a, and Rhino after NSL2 depletion. …”
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    The NSL complex is required for piRNA production from telomeric clusters
  14. 1094
    “…The relative quantity of telomere products, which is proportional to the average TL, was determined via multiplex quantitative PCR using the ratio (T/S ratio) of bovine telomere and β-globulin DNA. …”
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    Comparison of Telomere Length in Age-Matched Primiparous and Multiparous Brahman Cows
  15. 1095
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    Primary Scientific Literature Represents an Essential Source of Telomeric Repeat Sequences
  16. 1096
    “…Shelterin and nucleosomes are the key players that organize mammalian chromosome ends into the protective telomere caps. However, how they interact with each other at telomeres remains unknown. …”
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    Structural basis of telomeric nucleosome recognition by shelterin factor TRF1
  17. 1097
    “…Telomere length can be maintained either by the telomerase enzyme or by alternative lengthening of telomeres (ALT), which is based on telomeric recombination. …”
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    Inhibition of p53 and ATRX increases telomeric recombination in primary fibroblasts
  18. 1098
    “…BACKGROUND: Studies have shown that longer leukocyte telomere length (LTL) is significantly associated with increased risk of meningioma. …”
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    The causal relationship between genetically determined telomere length and meningiomas risk
  19. 1099
    “…Telomeres play pivotal roles in processes closely related to somatic senescence and aging, making them a compelling target for interventions aimed at combating aging and age-related pathologies. …”
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    Ginsenoside F1-Mediated Telomere Preservation Delays Cellular Senescence
  20. 1100
    “…Telomeres protect chromosome ends and determine the replication potential of dividing cells. …”
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    Fyn-mediated phosphorylation of Menin disrupts telomere maintenance in stem cells
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