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Mostrando 1,121 - 1,140 Resultados de 8,819 Para Buscar 'Telonero~', tiempo de consulta: 3.40s Limitar resultados
  1. 1121
    “…Telomere shortening represents a causal factor of cellular senescence. …”
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    Sod2 haploinsufficiency does not accelerate aging of telomere dysfunctional mice
  2. 1122
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    Oxidative stress induces chondrocyte telomere instability and chondrocyte dysfunctions in osteoarthritis
  3. 1123
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    Polymorphism within the telomeric MHC and expression of rheumatoid arthritis candidate genes
  4. 1124
    “…The transient Zscan4-positive state is associated with rapid telomere extension by telomere recombination and upregulation of meiosis-specific homologous recombination genes, which encode proteins that are colocalized with ZSCAN4 on telomeres. …”
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    Zscan4 regulates telomere elongation and genomic stability in ES cells
  5. 1125
    “…Telomeric repeats preserve genome integrity by stabilizing chromosomes, a function that appears to be important for both cancer and aging. …”
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    Human Telomeres Are Hypersensitive to UV-Induced DNA Damage and Refractory to Repair
  6. 1126
    “…It has both 3'-5' DNA helicase and exonuclease activities, and is suggested to have roles in many aspects of DNA metabolism, including DNA repair and telomere maintenance. The DNA-PK complex also functions in both DNA double strand break repair and telomere maintenance. …”
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    Cooperation of DNA-PKcs and WRN helicase in the maintenance of telomeric D-loops
  7. 1127
    “…Sir2 is recruited to telomeres through Rap1, and this complex spreads into subtelomeric DNA via histone deacetylation. …”
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    SIRT1 contributes to telomere maintenance and augments global homologous recombination
  8. 1128
    “…Telomere integrity in budding yeast depends on the CST (Cdc13-Stn1-Ten1) and shelterin-like (Rap1-Rif1-Rif2) complexes, which are thought to act independently from each other. …”
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    Rif1 Supports the Function of the CST Complex in Yeast Telomere Capping
  9. 1129
    “…Telomere maintenance and DNA repair are crucial processes that protect the genome against instability. …”
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    RTEL1: an essential helicase for telomere maintenance and the regulation of homologous recombination
  10. 1130
    “…The majority of chromosomal defects in human carcinomas comprises pericentromeric breaks that are captured by healthy telomeres, and only a minor proportion of chromosome fusions can be attributed to telomere erosion or random breakage. …”
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    Centromere fission, not telomere erosion, triggers chromosomal instability in human carcinomas
  11. 1131
    “…OBJECTIVE: Recent studies have identified a set of serological markers for telomere dysfunction and DNA damage. The relevance of these serological markers in type 2 diabetes remains elusive. …”
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    Telomere Dysfunction–Related Serological Markers Are Associated With Type 2 Diabetes
  12. 1132
    “…Accumulating evidence supports leukocyte telomere length (LTL) as a biological marker of cellular aging. …”
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    Shorter Leukocyte Telomere Length in Midlife Women with Poor Sleep Quality
  13. 1133
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    Natural isoflavones regulate the quadruplex–duplex competition in human telomeric DNA
  14. 1134
    “…BACKGROUND AND AIMS: Shorter telomeres have been associated with increased risk of malignancy, including colorectal cancer (CRC). …”
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    TERC polymorphisms are associated both with susceptibility to colorectal cancer and with longer telomeres
  15. 1135
    por Peng, Jing, Zhou, Jin-Qiu
    Publicado 2012
    “…Eukaryotic chromosome ends have a DNA–protein complex structure termed telomere. Integrity of telomeres is essential for cell proliferation. …”
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    The tail-module of yeast Mediator complex is required for telomere heterochromatin maintenance
  16. 1136
    “…BACKGROUND: Rupture of the fetal membranes is a common harbinger of imminent labor and delivery. Telomere shortening is a surrogate for oxidative stress (OS) and senescence. …”
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    Short Fetal Leukocyte Telomere Length and Preterm Prelabor Rupture of the Membranes
  17. 1137
    “…We have exploited two alternative cellular systems to test whether TERRA and/or telomere transcription influence telomerase-mediated telomere elongation in human cancer cells. …”
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    Telomerase Efficiently Elongates Highly Transcribing Telomeres in Human Cancer Cells
  18. 1138
    “…Telomere length, a biomarker of aging and age-related diseases, exhibits wide variation between individuals. …”
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    Association between Genetic Variants in DNA and Histone Methylation and Telomere Length
  19. 1139
    “…BACKGROUND: Chronic psychological distress has been linked to shorter telomeres, an indication of accelerated aging. Yet, little is known about relations of anxiety to telomeres. …”
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    High Phobic Anxiety Is Related to Lower Leukocyte Telomere Length in Women
  20. 1140
    “…We determined relative leukocyte telomere length using a quantitative real-time polymerase chain reaction (PCR) -based method. …”
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    Work-Related Exhaustion and Telomere Length: A Population-Based Study
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