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Mostrando 1,181 - 1,200 Resultados de 8,819 Para Buscar 'Telonero~', tiempo de consulta: 5.51s Limitar resultados
  1. 1181
    “…Adverse experiences in early life can exert powerful delayed effects on adult survival and health. Telomere attrition is a potentially important mechanism in such effects. …”
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    An experimental demonstration that early-life competitive disadvantage accelerates telomere loss
  2. 1182
    “…We tested the prediction that if, as has been suggested, developmental telomere attrition is a biomarker of state and future life expectancy, then individuals who have undergone greater developmental telomere attrition should display greater choice impulsivity as adults. …”
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    Developmental telomere attrition predicts impulsive decision-making in adult starlings
  3. 1183
    “…INTRODUCTION: Telomere length (TL) is a biomarker of accumulated cellular damage and human aging. …”
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    Physical activity and telomere length in early stage breast cancer survivors
  4. 1184
    “…In budding yeast, dicentrics generated by telomere fusion break at the fusion, a process that restores the parental karyotype and protects cells from rare accidental telomere fusion. …”
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    Cytokinesis breaks dicentric chromosomes preferentially at pericentromeric regions and telomere fusions
  5. 1185
    “…TRF2 is essential for telomere capping owing to its roles in suppressing an ATM-dependent DNA damage response (DDR) at chromosome ends and inhibiting end-to-end chromosome fusions. …”
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    Essential role for the TRF2 telomere protein in adult skin homeostasis
  6. 1186
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    Arrangements of human telomere DNA quadruplex in physiologically relevant K(+) solutions
  7. 1187
    por Suram, Anitha, Herbig, Utz
    Publicado 2014
    “…Telomeres, the ends of our linear chromosomes, can function as ‘replicometers’, capable of counting cell division cycles as they progressively erode with every round of DNA replication. …”
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    The replicometer is broken: telomeres activate cellular senescence in response to genotoxic stresses
  8. 1188
    “…Telomeres and centromeres have traditionally been considered to perform distinct roles. …”
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    Telomeres and centromeres have interchangeable roles in promoting meiotic spindle formation
  9. 1189
    “…BACKGROUND: Recent large-scale prospective studies suggest that long telomeres are associated with an increase cancer risk, counter to conventional wisdom. …”
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    Circulating leukocyte telomere length and risk of overall and aggressive prostate cancer
  10. 1190
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    Telomeric ORFS in Candida albicans: Does Mediator Tail Wag the Yeast?
  11. 1191
    “…BACKGROUND: Leucocyte telomere length (LTL), which is fashioned by multiple genes, has been linked to a host of human diseases, including sporadic melanoma. …”
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    DCAF4, a novel gene associated with leucocyte telomere length
  12. 1192
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    Telomere Reverse Transcriptase (TERT) rs2735940 Increases Cancer Risk
  13. 1193
    “…More than two decades of genetic research have identified and assigned main biological functions of shelterin proteins that safeguard telomeres. However, a molecular mechanism of how each protein subunit contributes to the protecting function of the whole shelterin complex remains elusive. …”
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    Human Rap1 modulates TRF2 attraction to telomeric DNA
  14. 1194
    “…Interestingly, telomeric enzymes and subtelomeric regions are subject to epigenetic modifications—a factor which may play an important role in regulating telomere length and contribute to future mental health. …”
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    The long-term impact of adverse caregiving environments on epigenetic modifications and telomeres
  15. 1195
    “…The conserved shelterin complex is critical for chromosome capping and maintaining telomere length homeostasis. In fission yeast, shelterin is comprised of five proteins. …”
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    Minishelterins separate telomere length regulation and end protection in fission yeast
  16. 1196
    “…Telomere shortening is common in bone marrow failure syndromes such as dyskeratosis congenita (DC), aplastic anemia (AA) and myelodysplastic syndromes (MDS). …”
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    Reversibility of Defective Hematopoiesis Caused by Telomere Shortening in Telomerase Knockout Mice
  17. 1197
    “…While our data affirm the role of TERT promoter mutations in glial tumors, effects on transcription and telomere length emphasise the importance of telomere biology in disease genesis and outcome.…”
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    TERT promoter mutations and telomere length in adult malignant gliomas and recurrences
  18. 1198
    “…The Borrelia telomere resolvase, ResT, forms the unusual hairpin telomeres of the linear Borrelia replicons in a process referred to as telomere resolution. …”
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    Spring loading a pre-cleavage intermediate for hairpin telomere formation
  19. 1199
    “…In mammals, protection is accomplished by a six-factor complex named shelterin, which organizes the terminal TTAGGG repeats in a still ill-defined structure, the telomere. The stable interaction of shelterin with telomeres mainly depends on the binding of two of its components, TRF1 and TRF2, to double-stranded telomeric repeats. …”
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    TRF1 and TRF2 binding to telomeres is modulated by nucleosomal organization
  20. 1200
    “…Fifteen per cent of cancers maintain telomere length independently of telomerase by the homologous recombination (HR)-associated alternative lengthening of telomeres (ALT) pathway. …”
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    Suppression of the alternative lengthening of telomere pathway by the chromatin remodelling factor ATRX
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