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Mostrando 1,261 - 1,280 Resultados de 8,819 Para Buscar 'Telonero~', tiempo de consulta: 4.38s Limitar resultados
  1. 1261
    “…A shorter telomere length is associated with several systemic disorders. …”
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    Examining the association between anthropometric parameters and telomere length and mortality risk
  2. 1262
    “…Emerging evidence suggests that epigenetics regulates telomere dynamics in adults. However, the relationship between these pathways in children and youth remains unknown. …”
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    Associations between Global DNA Methylation and Telomere Length in Healthy Adolescents
  3. 1263
    “…Mounting evidence suggests that average telomere length reflects previous stress and predicts subsequent survival across vertebrate species. …”
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    Sex differences in leucocyte telomere length in a free‐living mammal
  4. 1264
    “…Complex 2 c also has higher selectivity towards human telomeric dimeric quadruplexes with one TTA linker than the monometallic complex 1. …”
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    Dinickel–Salphen Complexes as Binders of Human Telomeric Dimeric G‐Quadruplexes
  5. 1265
    “…By measuring telomerase activity at the single-cell level using quantitative ddPCR techniques (ddTRAP) and by monitoring changes in the shortest telomeres with more sensitive telomere length measurement assays, we show that only a subset of CD28+ T-cells have robust telomerase activity upon stimulation and are capable of maintaining their telomere lengths during induced proliferation. …”
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    The Maintenance of Telomere Length in CD28+ T Cells During T Lymphocyte Stimulation
  6. 1266
    “…OBJECTIVE: We investigated the relationship between diabetes and telomere length by meta-analysis. METHODS: We searched five popular databases for articles published between 1990 and 2015 using “diabetes” and “telomere” as search terms. …”
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    Association between telomere length and diabetes mellitus: A meta-analysis
  7. 1267
    “…Telomeres protect the ends of vertebrate chromosomes from deterioration and consist of tandem nucleotide repeats (TTAGGG)(n) that are associated with a number of proteins. …”
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    Telomeres and Telomerase: Role in Marek’s Disease Virus Pathogenesis, Integration and Tumorigenesis
  8. 1268
    por Zhao, Yilin, Li, Shijun, Liu, Hui
    Publicado 2017
    “…BACKGROUND: This study aimed to establish a model that estimates the survival advantage at the molecular level based on telomere length and serum biomarkers of aging, to explore clinical significance. …”
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    Estimating the survival advantage based on telomere length and serum biomarkers of aging
  9. 1269
    “…Telomeres protect the integrity of information-carrying DNA by serving as caps on the terminal portions of chromosomes. …”
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    Physical activity and telomere length: Impact of aging and potential mechanisms of action
  10. 1270
    por Schmiester, Maren, Demuth, Ilja
    Publicado 2017
    “…As a shelterin accessory protein, hSNM1B/Apollo is also vital for the generation and maintenance of telomeric overhangs. In this review, we will summarize studies on hSNM1B/Apollo's function, including its contribution to DNA damage signaling, replication fork maintenance, control of topological stress and telomere protection. …”
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    SNM1B/Apollo in the DNA damage response and telomere maintenance
  11. 1271
    “…BACKGROUND: Leukocyte telomere length (LTL) is a potential biomarker of cancer prognosis; however, evidence for renal cell carcinoma (RCC) is inconsistent. …”
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    Leukocyte telomere length and renal cell carcinoma survival in two studies
  12. 1272
    “…The acquisition of unlimited proliferative potential is dependent on the activation of mechanisms for telomere maintenance, which counteracts telomere shortening and the consequent triggering of the DNA damage response, cell cycle arrest, and apoptosis. …”
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    Regulation of Telomere Homeostasis during Epstein-Barr virus Infection and Immortalization
  13. 1273
    “…By tracking the dynamics of telomeres visualized by CRISPR–dCas9, we reveal dynamic telomere movements of up to 2 μm over 30 min during interphase. …”
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    Live‐cell CRISPR imaging in plants reveals dynamic telomere movements
  14. 1274
    “…BACKGROUND: Telomeres undergo shortening with each cell division, which could be accelerated by increase obesity and is also related to endocrinology systems. …”
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    Longer Telomere Length and its Association with Lower Levels of C-Peptide
  15. 1275
    “…This dramatic movement involves clustering of telomeres at the nuclear membrane to form the so-called telomere bouquet. …”
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    The telomere bouquet facilitates meiotic prophase progression and exit in fission yeast
  16. 1276
    por Bellon, Marcia, Nicot, Christophe
    Publicado 2017
    “…The progressive loss of immunological memory during aging correlates with a reduced proliferative capacity and shortened telomeres of T cells. Growing evidence suggests that this phenotype is recapitulated during chronic viral infection. …”
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    Telomere Dynamics in Immune Senescence and Exhaustion Triggered by Chronic Viral Infection
  17. 1277
    por Sandhu, Ranjodh, Li, Bibo
    Publicado 2017
    “…Trypanosoma brucei causes fatal human African trypanosomiasis and evades the host immune response by regularly switching its major surface antigen, VSG, which is expressed exclusively from subtelomeric loci. Telomere length and telomere proteins play important roles in regulating VSG silencing and switching. …”
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    Telomerase activity is required for the telomere G-overhang structure in Trypanosoma brucei
  18. 1278
    “…Objective: The discovery of telomere length (TL) as a biomarker of cellular aging and correlate of age-related disease has generated a new field of research in the biology of healthy aging. …”
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    Validation of Minimally-Invasive Sample Collection Methods for Measurement of Telomere Length
  19. 1279
    “…Transcription of telomere repeats can initiate at subtelomeric CTCF-binding sites to generate telomere repeat-encoding RNA (TERRA), but the role of transcription, CTCF, and TERRA in telomere replication is not known. …”
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    CTCF driven TERRA transcription facilitates completion of telomere DNA replication
  20. 1280
    “…Telomere homeostasis is controlled by both telomerase machinery and end protection. …”
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    Telomere shortening triggers a feedback loop to enhance end protection
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