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Mostrando 1,301 - 1,320 Resultados de 8,819 Para Buscar 'Telonero~', tiempo de consulta: 5.01s Limitar resultados
  1. 1301
    “…Dynamics and mechanisms of telomere reprogramming of CiPSCs remain elusive. We show that CiPSCs acquire telomere lengthening with increasing passages after clonal formation. …”
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    Dynamics of Telomere Rejuvenation during Chemical Induction to Pluripotent Stem Cells
  2. 1302
    “…Inhibition of POT1 activates ATRdependent DNA damage signaling and induces telomere fragility, replication fork stalling, and telomere elongation. …”
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    Telomere Replication Stress Induced by POT1 Inactivation Accelerates Tumorigenesis
  3. 1303
    “…Genome regulatory programs such as telomere functioning require extracellular signals to be transmitted from the microenvironment to the nucleus and chromatin. …”
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    Actin Dynamics Couples Extracellular Signals to the Mobility and Molecular Stability of Telomeres
  4. 1304
    “…BACKGROUND: Several epidemiological studies had been carried out in different population cohorts to estimate the relationship between the shortened telomere length and stroke. However, the results still remained dispute. …”
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    Relationship between short telomere length and stroke: A meta-analysis
  5. 1305
    “…In this review, we summarized the information concerning the implication of telomere and telomerase modulation in cancer radiosensitivity.…”
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    Effect of therapies-mediated modulation of telomere and/or telomerase on cancer cells radiosensitivity
  6. 1306
    “…These deficiencies were instead linked to telomere defects, where PARP1(−/−) cells had short telomeres that co-localized with markers of endogenous DNA damage and were compromised in their ability to escape a telomere-driven crisis. …”
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    PARP1 is required for preserving telomeric integrity but is dispensable for A-NHEJ
  7. 1307
    “…Linear regression models were used to identify independent predictors of telomere length. RESULTS: We show that patients with NFPA exhibited shorter telomeres than controls. …”
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    Shorter telomeres associated with high doses of glucocorticoids: the link to increased mortality?
  8. 1308
    “…Telomere length (TL) is considered an indicator of aging and age-related diseases, but longitudinal studies on TL changes and mortality are few. …”
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    Longitudinal changes in leukocyte telomere length and mortality in elderly Swedish men
  9. 1309
    “…Leukocyte telomere shortening reflects stress burdens and has been associated with cardiac events. …”
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    Cardiac-Referenced Leukocyte Telomere Length and Outcomes After Cardiovascular Surgery
  10. 1310
    “…Here, we explored the impact of social experiences on circulating oxytocin (OT) concentration, telomere length (TL), and novelty-seeking behaviour in male and female rats. …”
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    Oxytocin-mediated social enrichment promotes longer telomeres and novelty seeking
  11. 1311
    “…As a proof of utility of this method, fluorescent PNA hybridization probes were developed and used in imaging human telomeres in chromosomes and poly(A) RNAs in cells. …”
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    Clickable PNA Probes for Imaging Human Telomeres and Poly(A) RNAs
  12. 1312
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    Author Correction: Telomere length and survival in primary cutaneous melanoma patients
  13. 1313
    “…The carbazole ligand 3 was synthesized, characterized and its binding interactions with human telomeric (22HT) G-quadruplex DNA in Na(+) and K(+)-containing buffer were investigated by ultraviolet-visible (UV-Vis) spectrophotometry, fluorescence, circular dichroism (CD) spectroscopy, and DNA melting. …”
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    Binding Study of the Fluorescent Carbazole Derivative with Human Telomeric G-Quadruplexes
  14. 1314
    “…Telomere length (TL) in offspring is positively correlated with paternal age at the time of the offspring conception. …”
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    Paternal Age and Transgenerational Telomere Length Maintenance: A Simulation Model
  15. 1315
    “…In addition, we have validated a number of genes whose expression is directly related to telomere length and these are potential fundamental biomarkers of aging that may influence the risk and progression of multiple aging conditions.…”
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    Telomere length and telomerase activity in T cells are biomarkers of high‐performing centenarians
  16. 1316
    “…After acute oxidative stress at telomeres, our data demonstrated a reduction in TRF1 and TRF2, which are involved in proper telomere replication and T-loop formation, respectively. …”
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    Oxidative Stress Induces Telomere Dysfunction and Senescence by Replication Fork Arrest
  17. 1317
    “…Cellular senescence, a process driven in part by telomere shortening, has been implicated in age‐related tissue dysfunction. …”
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    Length‐independent telomere damage drives post‐mitotic cardiomyocyte senescence
  18. 1318
    “…In vertebrates, the telomere repeat containing long, non-coding RNA TERRA is prone to form RNA:DNA hybrids at telomeres. …”
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    SFPQ and NONO suppress RNA:DNA-hybrid-related telomere instability
  19. 1319
    “…Reduced telomere length (TL) and structural brain abnormalities have been reported in patients with schizophrenia (SZ) and bipolar disorder (BD). …”
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    Telomere length is associated with childhood trauma in patients with severe mental disorders
  20. 1320
    “…Telomeric regions of the genome are inherently difficult-to-replicate due to their propensity to generate DNA secondary structures and form nucleoprotein complexes that can impede DNA replication fork progression. …”
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    Esc2 promotes telomere stability in response to DNA replication stress
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