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Mostrando 1,381 - 1,400 Resultados de 8,819 Para Buscar 'Telonero~', tiempo de consulta: 3.59s Limitar resultados
  1. 1381
    “…Background: Psychosocial stressors, such as perceived discrimination and depressive symptoms, may shorten telomeres and exacerbate aging-related illnesses. Methods: Participants from the Jackson Heart Study at visit 1 (2000–2004) with LTL data and Center for Epidemiological Studies-Depression (CES-D) scores (n = 580 men, n = 910 women) were utilized. …”
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    Discrimination and Leukocyte Telomere Length by Depressive Symptomatology: The Jackson Heart Study
  2. 1382
    “…Much about the primary etiology of this form of lymphopenia remains unknown, but regardless of its causes, offsetting the decline in T-cell count during SARS-CoV-2 infection demands fast and massive T-cell clonal expansion, which is telomere length (TL)-dependent. We have built a model that captures the effect of age-dependent TL shortening in hematopoietic cells and its effect on T-cell clonal expansion capacity. …”
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    Short Telomeres and a T-Cell Shortfall in COVID-19: The Aging Effect
  3. 1383
    “…Weight gain from non-obesity to obesity shortened the leukocyte telomere length by 0.094 kbp (95% CI: 0.012-0.177, P=0.026), while normal weight to overweight or remaining overweight shortened the leukocyte telomere length by 0.074 kbp (95% CI: 0.014-0.134, P=0.016). …”
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    Association Between Weight Change and Leukocyte Telomere Length in U.S. Adults
  4. 1384
    “…Introduction: Fibrotic interstitial lung diseases (ILDs) are the first indication for lung transplantation (LT). Telomere dysfunction has been associated with poor post-transplant outcomes. …”
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    Lung Transplant Improves Survival and Quality of Life Regardless of Telomere Dysfunction
  5. 1385
    “…Observational studies have revealed associations between short leucocyte telomere length (LTL), a TL marker in somatic tissues and multiple Metabolic Syndrome (MetS) traits. …”
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    Telomere length and metabolic syndrome traits: A Mendelian randomisation study
  6. 1386
    “…Human telomeric DNA with hundreds of repeats of the 5’‐TTAGGG‐3’ motif plays a crucial role in several biological processes. …”
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    The Binding Pocket at the Interface of Multimeric Telomere G‐quadruplexes: Myth or Reality?
  7. 1387
    “…Telomere repeat binding factor 2 (TRF2) has a well-known function at the telomeres, which acts to protect the telomere end from being recognized as a DNA break or from unwanted recombination. …”
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    The Intra- and Extra-Telomeric Role of TRF2 in the DNA Damage Response
  8. 1388
    “…BACKGROUND: Exposure to suboptimal intrauterine environment might induce structural and functional changes that can affect neonatal health. Telomere length as an important indicator of cellular health has been associated with increased risk for disease development. …”
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    Influence of Maternal Infection and Pregnancy Complications on Cord Blood Telomere Length
  9. 1389
    “…The relationship between METH use and accelerated biological aging, which can be measured using leukocyte telomere length (LTL), remains unclear. We examined whether young adult METH users have shorter LTL and explored the relationship between characteristics of METH use and LTL by using Mendelian randomization (MR) analysis. …”
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    Shortened leukocyte telomere length in young adults who use methamphetamine
  10. 1390
    “…Variants in a gene cluster upstream-adjacent to TERC on human chromosome 3, which includes genes APRM, LRRC31, LRRC34 and MYNN, have been associated with telomere length in several human populations. Currently, the mechanism by which variants in the TERC gene cluster influence telomere length in humans is unknown. …”
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    Terc Gene Cluster Variants Predict Liver Telomere Length in Mice
  11. 1391
    por Sung, Ji-Yong, Cheong, Jae-Ho
    Publicado 2021
    “…Understanding the telomere maintenance mechanism (TMM) in immortal cancer cells is vital for TMM-targeted therapies in clinical settings. …”
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    Pan-Cancer Analysis of Clinical Relevance via Telomere Maintenance Mechanism
  12. 1392
    “…Telomere length (TL) is a hallmark of cellular aging and is associated with chronic diseases development. …”
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    A genetic determinant of VEGF-A levels is associated with telomere attrition
  13. 1393
    “…Conclusion: Physical exercise programs can lead to an improvement in both cognitive functions and telomere length.…”
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    Effects of Physical Exercise on Cognition and Telomere Length in Healthy Older Women
  14. 1394
    “…Telomere length (TL) is progressively shortened as age progresses, thus resulting in cellular senescence. …”
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    Insights into the Role of Telomeres in Human Embryological Parameters. Opinions Regarding IVF
  15. 1395
    “…This review aims is to summarize the current understanding of the role of telomere length and epigenetic mechanisms on the severity of COVID-19. …”
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    Understanding the role of telomere attrition and epigenetic signatures in COVID-19 severity
  16. 1396
    “…Telomere length shortening is a known biomarker of aging and aging related diseases. …”
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    Maternal opioid use is reflected on leukocyte telomere length of male newborns
  17. 1397
    “…Introduction: Biological aging is associated with changes in the metabolic pathways. Leukocyte telomere length (LTL) is a predictive marker of biological aging; however, the underlying metabolic pathways remain largely unknown. …”
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    Metabolic Signature of Leukocyte Telomere Length in Elite Male Soccer Players
  18. 1398
    “…The junction between the double-stranded and single-stranded telomeric DNA (ds–ss junction) is fundamental in the maintenance of the telomeric chromatin, as it directs the assembly of the telomere binding proteins. …”
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    The telomeric 5′ end nucleotide is regulated in the budding yeast Naumovozyma castellii
  19. 1399
    “…ABSTRACT: Telomere length has attracted much interest as a topic of study in human reproduction; furthermore, the link between sperm telomere length and fertility outcomes has been investigated in other species. …”
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    Telomere Length in Pig Sperm Is Related to In Vitro Embryo Development Outcomes
  20. 1400
    “…The Cancer Genome Atlas data highlighted telomere/telomerase associated genes (TTAGs) with prognostic relevance in the endometrium, and a recent in silico study identified a group of TTAGs and proteins as key regulators within a network of dysregulated genes in EC. …”
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    Telomere and Telomerase-Associated Proteins in Endometrial Carcinogenesis and Cancer-Associated Survival
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