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Mostrando 1,401 - 1,420 Resultados de 8,819 Para Buscar 'Telonero~', tiempo de consulta: 4.48s Limitar resultados
  1. 1401
    “…Telomere is a unique DNA-protein complex which covers the ends of chromosomes to avoid end fusion and maintain the stability and integrity of chromosomes. …”
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    Telomere length is maternally inherited and associated with lipid metabolism in Chinese population
  2. 1402
    “…Physiologic aging leads to attrition of telomeres and replicative senescence. An acceleration of this process has been hypothesized in the progression of chronic liver disease. …”
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    Inverse Association of Telomere Length With Liver Disease and Mortality in the US Population
  3. 1403
    “…BACKGROUND: Telomeres are essential for chromosomal stability and may play a key role in carcinogenesis. …”
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    Telomere length in peripheral blood leukocytes and risk of renal cell carcinoma
  4. 1404
    “…Rif1 is a large multifaceted protein involved in various processes of DNA metabolism – from telomere length regulation and replication to double-strand break repair. …”
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    Telomere length regulation by Rif1 protein from Hansenula polymorpha
  5. 1405
    “…The susceptibility of telomeres to oxidizing molecules has led to the hypothesis that increased GC levels boost telomere shortening, but studies on this link are scanty. …”
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    Telomere shortening is associated with corticosterone stress response in adult barn swallows
  6. 1406
    “…G-quadruplex (G4) structures that can form at guanine-rich genomic sites, including telomeres and gene promoters, are actively involved in genome maintenance, replication, and transcription, through finely tuned interactions with protein networks. …”
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    Vimentin binds to G-quadruplex repeats found at telomeres and gene promoters
  7. 1407
    “…DNA methylation modulates telomere function. In Arabidopsis thaliana, telomeric regions have a bimodal chromatin organization with unmethylated telomeres and methylated subtelomeres. …”
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    A complex network of interactions governs DNA methylation at telomeric regions
  8. 1408
    “…Vitamin D deficiency is common among postmenopausal women. Telomere length can be a potential protective mechanism for age-related diseases. …”
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    Leukocyte telomere length as a compensatory mechanism in vitamin D metabolism
  9. 1409
    “…Recent studies have found that FA proteins are involved in the regulation of replication stress (RS) in alternative lengthening of telomeres (ALT). Since ALT cells often exhibit high-frequency ATRX mutations and high levels of telomeric secondary structure, high levels of DNA damage and replicative stress exist in ALT cells. …”
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    Regulation of Replication Stress in Alternative Lengthening of Telomeres by Fanconi Anaemia Protein
  10. 1410
    “…Objective: Telomere length (TL) is a robust marker of biological aging, and increased telomere attrition is noted in adults with obesity. …”
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    Association between Telomere Length and Pediatric Obesity: A Systematic Review
  11. 1411
    “…During the normal aging process, a series of events occur, such as a decrease in telomere length and a decrease in various cognitive functions, such as attention, memory, or perceptual-motor speed. …”
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    Analysis of Telomere Length and Its Implication in Neurocognitive Functions in Elderly Women
  12. 1412
    “…The family displays short telomeres and genetic anticipation. We found that POT1(L259S) is defective in binding the telomeric overhang, nuclear accumulation, negative regulation of telomerase, and lagging strand maintenance. …”
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    Telomere dysfunction implicates POT1 in patients with idiopathic pulmonary fibrosis
  13. 1413
    “…Cellular senescence is an irreversible cell arrest process, which is determined by a variety of complicated mechanisms, including telomere attrition, mitochondrial dysfunction, metabolic disorders, loss of protein homeostasis, epigenetic changes, etc. …”
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    Telomeres and Mitochondrial Metabolism: Implications for Cellular Senescence and Age-related Diseases
  14. 1414
    “…BACKGROUND: Short leukocyte telomere length is a biomarker associated with stress and morbidity in non-pregnant adults. …”
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    Leukocyte telomere dynamics across gestation in uncomplicated pregnancies and associations with stress
  15. 1415
    “…This is associated with accelerated cellular aging which can be estimated by telomere length (TL). However, specific determinants of shorter TL in BD are under-explored. …”
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    Associations between circadian misalignment and telomere length in BD: an actigraphy study
  16. 1416
    “…PURPOSE: Relative telomere length (RTL) is a biomarker for physiological aging. …”
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    Relative Telomere Length Is Associated With Age-Related Macular Degeneration in Women
  17. 1417
    “…[Image: see text] Telomeric DNA is guanine-rich and can adopt structures such as G-quadruplexes (GQs) and G-hairpins. …”
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    Ion-Dependent Conformational Plasticity of Telomeric G-Hairpins and G-Quadruplexes
  18. 1418
    “…SCNT embryos suffer from poor developmental competence (both in vitro and in vivo) due to various defects such as oxidative stress, incomplete epigenetic reprogramming, and flaws in telomere rejuvenation. It is very promising to ameliorate all these defects in SCNT embryos by supplementing the culture medium with a single compound. …”
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    Melatonin accelerates the developmental competence and telomere elongation in ovine SCNT embryos
  19. 1419
    “…This work is a review of preclinical and clinical studies of the role of telomeres and telomerase in the development and progression of coronary heart disease (CHD). …”
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    Leukocyte Telomere Length as a Molecular Biomarker of Coronary Heart Disease
  20. 1420
    “…Background: Observational studies have suggested that there may be an association between telomere length (TL) and hearing loss (HL). However, inferring causality from observational studies is subject to residual confounding effects, reverse causation, and bias. …”
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    Telomere Length and Hearing Loss: A Two-Sample Mendelian Randomization
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