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  1. 1441
    “…BACKGROUND: With the progression of next‐generation sequencing technologies, researchers have identified numerous variants of the regulator of telomere elongation helicase 1 (RTEL1) gene that are associated with a broad spectrum of phenotypic manifestations, including malignancies. …”
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    Regulator of telomere elongation helicase 1 gene and its association with malignancy
  2. 1442
    “…Increasing age is associated with severity and higher mortality of COVID‐19. Telomere shortening is associated with higher risk of infections and may be used to identify those patients who are more likely to die. …”
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    Relative telomere length impact on mortality of COVID‐19: Sex differences
  3. 1443
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    Peripheral Blood Telomere Attrition in Persons at Risk for Familial Pulmonary Fibrosis
  4. 1444
    “…Variations in telomere length (TL) have been associated with aging, stress, and many diseases. …”
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    Placental telomere length shortening is not associated with severe preeclampsia but the gestational age
  5. 1445
    por Falker-Gieske, Clemens
    Publicado 2023
    “…BACKGROUND: With the first complete draft of a human genome, the Telomere-to-Telomere Consortium unlocked previously concealed genomic regions for genetic analyses. …”
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    Transcriptome driven discovery of novel candidate genes for human neurological disorders in the telomer-to-telomer genome assembly era
  6. 1446
    “…Human telomeric DNA G-quadruplex has been considered as an attractive target for cancer therapeutic intervention. …”
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    Structure of a two-G-tetrad intramolecular G-quadruplex formed by a variant human telomeric sequence in K(+) solution: insights into the interconversion of human telomeric G-quadruplex structures
  7. 1447
    “…The alternative lengthening of telomeres (ALT) facilitates telomere lengthening by a DNA strand invasion and copying mechanism. …”
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    The absence of (TCAGGG)(n) repeats in some telomeres, combined with variable responses to NR2F2 depletion, suggest that this nuclear receptor plays an indirect role in the alternative lengthening of telomeres
  8. 1448
    “…Leukocyte telomere length (LTL) represents a key integrating component of the cumulative effects of environmental, lifestyle, and genetic factors. …”
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    Longer Leukocytes Telomere Length Predicts a Significant Survival Advantage in the Elderly TRELONG Cohort, with Short Physical Performance Battery Score and Years of Education as Main Determinants for Telomere Elongation
  9. 1449
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    P803: TELOMERE SHORTENING IN BONE MARROW MESENCHYMAL STEM CELLS OF ACQUIRED APLASTIC ANEMIA PATIENTS ASSOCIATE WITH ALTERED EXPRESSION OF GENES INVOLVED IN TELOMERE MAINTENANCE, DNA DAMAGE, AND SENESCENCE
  10. 1450
    por Chávez-Chavira, Grecia
    Publicado 2023
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    Revisión del síndrome post-COVID-19 asociado a efluvio telógeno agudo
  11. 1451
    “…Telomeric G-quadruplexes (G4s) are promising targets in the design and development of anticancer drugs. …”
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    Polymorphism and Ligand Binding Modulate Fast Dynamics of Human Telomeric G-Quadruplexes
  12. 1452
    “…Telomere healing occurs when telomerase, normally restricted to chromosome ends, acts upon a double-strand break to create a new, functional telomere. …”
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    A comprehensive map of hotspots of de novo telomere addition in Saccharomyces cerevisiae
  13. 1453
    “…BACKGROUND: Canonical telomeres (telomerase-synthetised) are readily forming G-quadruplexes (G4) on the G-rich strand. …”
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    Telomeric retrotransposons show propensity to form G-quadruplexes in various eukaryotic species
  14. 1454
    “…Telomeres are terminal chromosomal elements that are essential for the maintenance of genomic integrity. …”
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    Chromogenic detection of telomere lengths in situ aids the identification of precancerous lesions in the prostate
  15. 1455
    por Wang, Huixue, Pan, Hui, Huang, Xiaolin
    Publicado 2023
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    AURKB Enhances Chromosomal Remodeling of Telomeric Genes and Accelerates Tumorigenesis of Uveal Melanoma
  16. 1456
    “…RESULTS: Statistical evaluation of relative telomere length was calculated by the ratio of telomere to single-copy gene for teratozoospermia and normal specimens. …”
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    Is sperm telomere length altered in teratozoospermia specimens? A case-control study
  17. 1457
    “…Links between telomere maintenance and the NE have been well established in yeast, in which telomere tethering to the NE is critical for their preservation and beyond. …”
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    Close Ties between the Nuclear Envelope and Mammalian Telomeres: Give Me Shelter
  18. 1458
    “…Therefore, given previously known factors which are associated with high mutation rates, we analyzed how many genes encoding druggable kinases match (i) proximity to telomeres or (ii) high A+T content. We extracted this genomic information using the National Institute of Health Genome Data Viewer. …”
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    Mutability of druggable kinases and pro-inflammatory cytokines by their proximity to telomeres and A+T content
  19. 1459
    “…We aimed to examine the correlation between urinary TCS exposure and BC risk and estimated the mediating effects of oxidative stress and relative telomere length (RTL) in the above association. METHODS: This case-control study included 302 BC patients and 302 healthy individuals in Wuhan, China. …”
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    Triclosan is associated with breast cancer via oxidative stress and relative telomere length
  20. 1460
    “…Telomere maintenance requires extension of the G-rich telomeric repeat strand by telomerase and fill-in synthesis of the C-rich strand by Polα/Primase. …”
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    POT1 recruits and regulates CST–Polα/Primase at human telomeres
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