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Mostrando 1,481 - 1,500 Resultados de 8,819 Para Buscar 'Telonero~', tiempo de consulta: 4.61s Limitar resultados
  1. 1481
    “…BACKGROUND: Studies suggest a harmful pharmacogenomic interaction exists between short leukocyte telomere length (LTL) and immunosuppressants in idiopathic pulmonary fibrosis (IPF). …”
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    Telomere length and immunosuppression in non-idiopathic pulmonary fibrosis interstitial lung disease
  2. 1482
    “…Reduced stability and different topology of lengthy telomeric tails could contribute to the stepwise telomere shortening process.…”
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    Guanine tetraplex topology of human telomere DNA is governed by the number of (TTAGGG) repeats
  3. 1483
    “…J is located in the telomeric sequences of Trypanosoma brucei and in other simple repeat DNA sequences. …”
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    Telomeric localization of the modified DNA base J in the genome of the protozoan parasite Leishmania
  4. 1484
    “…RecQ helicases, including Saccharomyces cerevisiae Sgs1p and the human Werner syndrome protein, are important for telomere maintenance in cells lacking telomerase activity. …”
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    Evidence That a RecQ Helicase Slows Senescence by Resolving Recombining Telomeres
  5. 1485
    “…The Saccharomyces cerevisiae Pif1p helicase is a negative regulator of telomere length that acts by removing telomerase from chromosome ends. …”
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    Sensitivity of Yeast Strains with Long G-Tails to Levels of Telomere-Bound Telomerase
  6. 1486
    “…The study of P-element repression in Drosophila melanogaster led to the discovery of the telomeric Trans-Silencing Effect (TSE), a repression mechanism by which a transposon or a transgene inserted in subtelomeric heterochromatin (Telomeric Associated Sequence or TAS) has the capacity to repress in trans in the female germline, a homologous transposon, or transgene located in euchromatin. …”
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    Telomeric Trans-Silencing: An Epigenetic Repression Combining RNA Silencing and Heterochromatin Formation
  7. 1487
    Publicado 1993
    “…Fluorescence in situ hybridization (FISH) shows that fission yeast centromeres and telomeres make up specific spatial arrangements in the nucleus. …”
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    Cell cycle-dependent specific positioning and clustering of centromeres and telomeres in fission yeast
  8. 1488
    Publicado 1996
    “…Telomeres have been shown to gradually shorten during replicative aging in human somatic cells by Southern analysis. …”
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    In situ analysis of changes in telomere size during replicative aging and cell transformation
  9. 1489
    “…In yeast meiosis, deficiency for Rec8 cohesin subunit induces telomere clustering to persist, whereas telomere cluster–SPB colocalization is defective. …”
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    Meiotic telomere clustering requires actin for its formation and cohesin for its resolution
  10. 1490
    “…Telomeres terminate in 3′ overhangs that function in end protection and the formation of t-loops. …”
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    Quantitative telomeric overhang determination using a double-strand specific nuclease
  11. 1491
    “…In both wild-type and checkpoint-mutant cells, regions near telomeres were particularly susceptible to re-replication. …”
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    Checkpoint effects and telomere amplification during DNA re-replication in fission yeast
  12. 1492
    “…Circular dichroism spectroscopy reveals that the porphyrin binds to Tetrahymena telomeric repeat to form G-quadruplex under stabilizing-cation-deficient and no buffer conditions.…”
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    Cationic Porphyrin Induced a Telomeric DNA to G-Quadruplex Form in Water
  13. 1493
    “…Human chromosome ends are protected with kilobases repeats of TTAGGG. Telomere DNA shortens at replication. This shortening in most tumor cells is compensated by telomerase that adds telomere repeats to the 3′ end of the G-rich telomere strand. …”
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    G-quadruplex preferentially forms at the very 3′ end of vertebrate telomeric DNA
  14. 1494
    “…The ends of eukaryotic chromosomes are protected by telomeres, nucleoprotein structures that are essential for chromosomal stability and integrity. …”
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    A systems-level approach to mapping the telomere length maintenance gene circuitry
  15. 1495
    “…Telomeres, consisting of TTAGGG nucleotide repeats and a protein complex at chromosome ends, are critical for maintaining chromosomal stability. …”
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    Genetic variation in five genes important in telomere biology and risk for breast cancer
  16. 1496
    “…Telomeres are maintained by three DNA-binding proteins (telomeric repeat binding factor 1 [TRF1], TRF2, and protector of telomeres 1 [POT1]) and several associated factors. …”
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    Telomere dysfunction and cell survival: roles for distinct TIN2-containing complexes
  17. 1497
    “…Little is known about the roles of the chromosome movement and telomere clustering in this phase. In budding yeast, telomere clustering is promoted by a meiosis-specific, telomere-binding protein, Ndj1. …”
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    Csm4-Dependent Telomere Movement on Nuclear Envelope Promotes Meiotic Recombination
  18. 1498
    “…Shelterin/telosome is a multi-protein complex at mammalian telomeres, anchored to the double-stranded region by the telomeric-repeat binding factors-1 and -2. …”
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    Rapid regulation of telomere length is mediated by poly(ADP-ribose) polymerase-1
  19. 1499
    “…The clinical manifestations of autosomal dominant DC are thought to occur when telomeres become critically short, but the rate of telomere shortening in this condition is unknown. …”
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    Telomerase reverse transcriptase haploinsufficiency and telomere length in individuals with 5p– syndrome
  20. 1500
    “…Telomeres in Drosophila are maintained by the specialized telomeric retrotransposons HeT-A, TART and TAHRE. …”
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    rasiRNA pathway controls antisense expression of Drosophila telomeric retrotransposons in the nucleus
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