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Mostrando 1,541 - 1,560 Resultados de 8,819 Para Buscar 'Telonero~', tiempo de consulta: 3.38s Limitar resultados
  1. 1541
    por Her, Yoon Ra, Chung, In Kwon
    Publicado 2013
    “…The human telomeric protein TRF2 is required to protect chromosome ends by facilitating their organization into the protective capping structure. …”
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    p300-mediated acetylation of TRF2 is required for maintaining functional telomeres
  2. 1542
    “…We employed three strictly related sequences based on the human telomeric repeat, namely Tel22, Tel26 and wtTel26, which assume distinct conformations in potassium containing solutions. …”
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    Effect of G-Quadruplex Polymorphism on the Recognition of Telomeric DNA by a Metal Complex
  3. 1543
    “…Structural models of the complexes with the telomeric DNA G-quadruplex based on NMR measurements were developed and further examined by molecular dynamics simulations and free energy calculations. …”
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    Structure and Stability of Human Telomeric G-Quadruplex with Preclinical 9-Amino Acridines
  4. 1544
    “…The discovery that telomeres are transcribed into telomere repeat containing RNA (TERRA) has revolutionized our view of this repetitive, rather unappreciated region of the genome. …”
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    TERRA, hnRNP A1, and DNA-PKcs Interactions at Human Telomeres
  5. 1545
    por Teixeira, M. Teresa
    Publicado 2013
    “…In many somatic human tissues, telomeres shorten progressively because of the DNA-end replication problem. …”
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    Saccharomyces cerevisiae as a Model to Study Replicative Senescence Triggered by Telomere Shortening
  6. 1546
    “…Drosophila lacks telomerase and fly telomeres are elongated by occasional transposition of three specialized retroelements. …”
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    Organization and Evolution of Drosophila Terminin: Similarities and Differences between Drosophila and Human Telomeres
  7. 1547
    “…Additionally, antidepressants have been found to protect against telomere shortening. However, pharmacological telomere studies are lacking in bipolar disorder (BD). …”
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    Long-term lithium treatment in bipolar disorder is associated with longer leukocyte telomeres
  8. 1548
    “…All p telomeres changed their position significantly during the activation process, although the effect was less pronounced for the q telomeres. …”
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    3D organization of telomeres in porcine neutrophils and analysis of LPS-activation effect
  9. 1549
    “…BACKGROUND: Telomeres are involved in cellular ageing and shorten with increasing age. …”
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    Telomere Length and Physical Performance at Older Ages: An Individual Participant Meta-Analysis
  10. 1550
    “…Cardiovascular disease and diabetes have been linked to shorter telomeres, but it is not yet clear which risk factors contribute to shorter telomeres in patients. …”
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    The Effect of Pro-Inflammatory Conditioning and/or High Glucose on Telomere Shortening of Aging Fibroblasts
  11. 1551
    “…Earlier studies have shown an association between telomere shortening and advanced MDS and underlined the important role of dysfunctional telomeres in the development of genetic instability and cancer. …”
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    Induction of Chromosomal Instability via Telomere Dysfunction and Epigenetic Alterations in Myeloid Neoplasia
  12. 1552
    “…Short leukocyte telomere length (LTL) is associated with atherosclerosis in adults and diminished survival in the elderly. …”
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    Tracking and fixed ranking of leukocyte telomere length across the adult life course
  13. 1553
    “…Aberrant telomere homeostasis is essential for cell immortality, enabling cells to evade telomere dependent senescence. …”
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    Targeting the telomere and shelterin complex for cancer therapy: current views and future perspectives
  14. 1554
    por Long, Xi, Stone, Michael D.
    Publicado 2013
    “…Telomeres are specialized chromatin structures found at the end of chromosomes and are crucial to the maintenance of eukaryotic genome stability. …”
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    Kinetic Partitioning Modulates Human Telomere DNA G-Quadruplex Structural Polymorphism
  15. 1555
    “…In all eight cases, the reporter insertion sites lie in the telomeric transposon array (HeT-A and TART-B2 homologous repeats) of the Y chromosome short arm (Ys). …”
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    A Distinct Type of Heterochromatin at the Telomeric Region of the Drosophila melanogaster Y Chromosome
  16. 1556
    “…However, the association between plasma inflammatory marker concentrations and telomere length has been inconsistent in previous studies. …”
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    The Relationship between Inflammatory Biomarkers and Telomere Length in an Occupational Prospective Cohort Study
  17. 1557
    “…This study aimed to determine whether telomere length (TL) is a marker of cancer risk or genetic status amongst two cohorts of BRCA1 and BRCA2 mutation carriers and controls. …”
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    Telomere Length Shows No Association with BRCA1 and BRCA2 Mutation Status
  18. 1558
    “…Telomeres are terminal repetitive DNA sequences on chromosomes, and are considered to comprise almost exclusively hexameric TTAGGG repeats. …”
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    Telomere extension by telomerase and ALT generates variant repeats by mechanistically distinct processes
  19. 1559
    “…Telomeric and subtelomeric regions of human chromosomes largely consist of highly repetitive and redundant DNA sequences, resulting in a paucity of unique DNA sequences specific to individual telomeres. …”
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    A Human Artificial Chromosome Recapitulates the Metabolism of Native Telomeres in Mammalian Cells
  20. 1560
    “…The mechanism of activation of the Alternative Lengthening of Telomeres (ALT) pathway of mammalian chromosome end maintenance has remained an unresolved issue. …”
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    Rapid induction of Alternative Lengthening of Telomeres by depletion of the histone chaperone ASF1
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