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Mostrando 141 - 160 Resultados de 8,819 Para Buscar 'Telonero~', tiempo de consulta: 3.30s Limitar resultados
  1. 141
    “…During tumorigenesis, cells have to acquire telomere DNA maintenance mechanisms (TMMs) in order to counteract telomere shortening, to preserve telomeres from DNA damage repair systems and to avoid telomere-mediated senescence and/or apoptosis. …”
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    Telomere Length Maintenance in Cancer: At the Crossroad between Telomerase and Alternative Lengthening of Telomeres (ALT)
  2. 142
    “…To form a new heterochromatic region in S. pombe, an inducible DNA double-strand break (DSB) was engineered next to 48 bp of telomere repeats in euchromatin, which caused formation of a new telomere and the establishment and gradual spreading of a new heterochromatin domain. …”
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    A Heterochromatin Domain Forms Gradually at a New Telomere and Is Dynamic at Stable Telomeres
  3. 143
    “…Enhanced telomere maintenance is evident in malignant cancers. …”
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    Local enrichment of HP1alpha at telomeres alters their structure and regulation of telomere protection
  4. 144
    “…Telomeric Repeat Binding Factors (TRFs) are architectural nuclear proteins with critical roles in telomere-length regulation, chromosome end protection and, fusion prevention, DNA damage detection, and senescence regulation. …”
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    Telomeric Repeat-Binding Factor Homologs in Entamoeba histolytica: New Clues for Telomeric Research
  5. 145
    “…Telomere-binding proteins constituting the shelterin complex have been studied primarily for telomeric functions. …”
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    Telomere length-dependent transcription and epigenetic modifications in promoters remote from telomere ends
  6. 146
    “…Large insertions, deletions and translocations could be observed along with evidence of transfer events between strains. In addition, the telomere and its cognate terminal protein complexes required for terminal replication and chromosome maintenance, were shown to be variable within the population probably reflecting telomere exchanges between the chromosome and other linear replicons (i.e., plasmids). …”
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    Telomeric and sub-telomeric regions undergo rapid turnover within a Streptomyces population
  7. 147
    “…Here we show that when BIR encounters an interstitial telomere sequence (ITS), the machinery frequently terminates, resulting in the formation of an ectopic telomere. …”
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    Interstitial telomere sequences disrupt break-induced replication and drive formation of ectopic telomeres
  8. 148
    “…The telomeric shelterin protein telomeric repeat-binding factor 2 (TRF2) recruits origin recognition complex (ORC) proteins, the foundational building blocks of DNA replication origins, to telomeres. …”
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    TRF2 Mediates Replication Initiation within Human Telomeres to Prevent Telomere Dysfunction
  9. 149
    “…Assortative mating by telomere lengths has been observed in several bird species, and in some cases may increase fitness of individuals. …”
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    Telomere lengths correlate with fitness but assortative mating by telomeres confers no benefit to fledgling recruitment
  10. 150
    “…Significantly, the binding frequency per telomeric repeat monotonically decreased with increasing telomere length. …”
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    Interrogating accessibility of telomeric sequences with FRET-PAINT: evidence for length-dependent telomere compaction
  11. 151
    “…Telomere attrition has been proposed as a biomarker and causal factor in aging. …”
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    Age‐related telomere attrition causes aberrant gene expression in sub‐telomeric regions
  12. 152
    “…Telomere length (TL) and telomere shortening are biological indicators of aging, and epigenetic associates have been found for TL in adults. …”
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    Different epigenetic signatures of newborn telomere length and telomere attrition rate in early life
  13. 153
    “…BRCA2-deficient cells precipitate telomere shortening upon collapse of stalled replication forks. …”
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    Dynamic interaction of BRCA2 with telomeric G-quadruplexes underlies telomere replication homeostasis
  14. 154
    por Stock, Amanda J, Liu, Yie
    Publicado 2021
    “…Telomeres are specialized nucleoprotein structures that form protective caps at the ends of chromosomes. …”
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    NAD-Linked Metabolism and Intervention in Short Telomere Syndromes and Murine Models of Telomere Dysfunction
  15. 155
    “…Oxidative damage to telomeric DNA has been proposed to cause premature senescence by accelerating telomere shortening. …”
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    Telomeric 8-oxo-guanine drives rapid premature senescence in the absence of telomere shortening
  16. 156
    “…Telomeres are specialized nucleoprotein complexes that function to protect eukaryotic chromosomes from recombination and erosion. …”
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    Telomere association of Oryza sativa telomere repeat-binding factor like 1 and its roles in telomere maintenance and development in rice, Oryza sativa L.
  17. 157
    Publicado 1975
    Libro
    Producción de terneros destetados /
  18. 158
    por Fuller, Richard
    Publicado 2000
    Materias: “…Terneros Cría y desarrollo.…”
    Libro
    Producción de terneros mamones
  19. 159
    por Armanios, Mary
    Publicado 2022
    “…Telomere biology was first studied in maize, ciliates, yeast, and mice, and in recent decades, it has informed understanding of common disease mechanisms with broad implications for patient care. …”
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    The Role of Telomeres in Human Disease
  20. 160
    por Kalmykova, Alla
    Publicado 2023
    “…The maintenance of genome integrity through generations is largely determined by the stability of telomeres. Increasing evidence suggests that telomere dysfunction may trigger changes in cell fate, independently of telomere length. …”
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    Telomere Checkpoint in Development and Aging
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