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  1. 1601
    “…Leukocyte telomere length (LTL) has been inversely associated with sugar-sweetened beverage (SSB) consumption in cross-sectional studies, but no studies have examined whether dietary intake influences LTL over time. …”
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    Sugary beverage and food consumption, and leukocyte telomere length maintenance in pregnant women
  2. 1602
    “…AIMS: Telomeres undergo shortening with cell division, accelerated by increased oxidative stress. …”
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    Leukocyte Telomere Length in the Neonatal Offspring of Mothers with Gestational and Pre-Gestational Diabetes
  3. 1603
    “…We have previously demonstrated that familial papillary thyroid cancer (fPTC) cells exhibit short relative telomere length (RTL) in both blood and tissues and that these features may be associated with chromosome instability. …”
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    Genetic Heterogeneity of HER2 Amplification and Telomere Shortening in Papillary Thyroid Carcinoma
  4. 1604
    “…Whether protection can be enhanced to counteract the age-dependent decline in telomere integrity is a challenging question. Telomeric repeat–containing RNA (TERRA), which is transcribed from telomeres, emerged as important player in telomere integrity. …”
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    Nuclear respiratory factor 1 and endurance exercise promote human telomere transcription
  5. 1605
    “…Telomeres are specialized nucleoprotein complexes that comprise the ends of linear chromosomes. …”
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    Dynamic peptides of human TPP1 fulfill diverse functions in telomere maintenance
  6. 1606
    “…However, Ku is also known to bind directly to telomeric DNA ends and its presence there is associated with telomere capping, but avoiding NHEJ. …”
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    Ku Binding on Telomeres Occurs at Sites Distal from the Physical Chromosome Ends
  7. 1607
    “…Here we employed single-molecule FRET microscopy to obtain a direct view of the folding and underlying conformational dynamics of G4s formed by the human telomeric sequence in potassium containing solutions. …”
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    A direct view of the complex multi-pathway folding of telomeric G-quadruplexes
  8. 1608
    “…BMI at age 25 and overweight trajectories were assessed using self-reported history. Leukocyte telomere length (LTL) relative to a standard DNA reference (T/S ratio) was quantified by polymerase chain reaction (PCR). …”
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    Investigating the associations between adiposity, life course overweight trajectories, and telomere length
  9. 1609
    “…The expression of Cdc13-Est2 fusion protein resulted in overlong telomeres (2 to 4 folds longer than normal telomeres), and long telomeres were stably maintained during long-term chronological aging. …”
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    Tethering telomerase to telomeres increases genome instability and promotes chronological aging in yeast
  10. 1610
    “…Telomere length maintenance ensures self-renewal of human embryonic stem cells (hESCs) and induced pluripotent stem cells (iPSCs), however the mechanisms governing telomere length homeostasis in these cell types are unclear. …”
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    A balance between elongation and trimming regulates telomere stability in stem cells
  11. 1611
    “…Selenium (Se) is a trace metalloid essential for life, but its nutritional and physiological roles during the aging process remain elusive. While telomere attrition contributes to replicative senescence mainly through persistent DNA damage response, such an aging process is mitigated in mice with inherently long telomeres. …”
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    Opposing impacts on healthspan and longevity by limiting dietary selenium in telomere dysfunctional mice
  12. 1612
    “…BACKGROUND & OBJECTIVES: Telomere plays a critical role in the maintenance of genomic stability in eukaryotic chromosomes. …”
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    Association of telomere length in peripheral leukocytes with chronic hepatitis B and hepatocellular carcinoma
  13. 1613
    “…OBJECTIVE: Whereas few adenomas become cancer, most colorectal cancers arise from adenomas. Telomere length is a recognized biomarker in multiple cancers, and telomere maintenance mechanisms (TMM) are exploited by malignant cells. …”
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    Time Lapse to Colorectal Cancer: Telomere Dynamics Define the Malignant Potential of Polyps
  14. 1614
    “…Most ovarian cancer patients present at an advanced stage with poor prognosis. Telomeres play a critical role in protecting chromosomes stability. …”
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    Genetic variants in telomere‐maintenance genes are associated with ovarian cancer risk and outcome
  15. 1615
    “…KEY POINTS: Age significantly modifies the relationship between aortic pulse wave velocity and telomere length. The differential relationships observed between aortic pulse wave velocity and telomere length in younger and older individuals suggest that the links between cellular and vascular ageing reflect a complex interaction between genetic and environmental factors acting over the life‐course. …”
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    The age‐dependent association between aortic pulse wave velocity and telomere length
  16. 1616
    “…Here we link fish oil, docosahexaenoic acid (DHA) and arachidonic acid (AA) to the aging etiology via a redox-telomere-antioncogene axis based on D-galactose-induced aging mice. …”
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    Polyunsaturated fatty acids ameliorate aging via redox-telomere-antioncogene axis
  17. 1617
    “…G-quadruplexes (G4s) are higher-order DNA structures typically present at promoter regions of genes and telomeres. Here, the G4 formation decreases the replicative DNA at each cell cycle, finally leading to apoptosis. …”
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    Ligand binding to telomeric G-quadruplex DNA investigated by funnel-metadynamics simulations
  18. 1618
    “…The CST complex is a phylogenetically conserved protein complex consisting of CTC1/Cdc13, Stn1 and Ten1 that protects telomeres on linear chromosomes. Deletion of the fission yeast homologs stn1 and ten1 results in complete telomere loss; however, the precise function of Stn1 is still largely unknown. …”
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    Fission yeast Stn1 is crucial for semi-conservative replication at telomeres and subtelomeres
  19. 1619
    “…BACKGROUND: Epidemiological studies have probed the correlation between telomere length and the risk of lung cancer, but their findings are inconsistent in this regard. …”
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    Is Leukocyte Telomere Length Related with Lung Cancer Risk?: A Meta-Analysis
  20. 1620
    “…Telomeres are protected by shelterin, a six-subunit protein complex that represses the DNA damage response (DDR) at chromosome ends. …”
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    The DDR at telomeres lacking intact shelterin does not require substantial chromatin decompaction
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