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  1. 1621
    “…POT1 and TPP1 are part of the shelterin complex and are essential for telomere length regulation and maintenance. Naturally occurring mutations of the telomeric POT1–TPP1 complex are implicated in familial glioma, melanoma and chronic lymphocytic leukaemia. …”
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    Structural and functional analysis of the human POT1-TPP1 telomeric complex
  2. 1622
    “…INTRODUCTION: Short telomere length has been suggested to be associated with atherosclerotic changes in Western populations. …”
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    Short telomere length is associated with renal impairment in Japanese subjects with cardiovascular risk
  3. 1623
    “…Telomeres have been studied extensively in peripheral tissues, but their relevance in the nervous system remains poorly understood. …”
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    Different requirements of functional telomeres in neural stem cells and terminally differentiated neurons
  4. 1624
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    Time Lapse to Colorectal Cancer: Telomere Dynamics Define the Malignant Potential of Polyps
  5. 1625
    “…The association between telomere length (TL) dynamics on cognitive performance over the life-course is not well understood. …”
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    Short telomere length is associated with impaired cognitive performance in European ancestry cohorts
  6. 1626
    “…Telomeres at the ends of eukaryotic chromosomes play a critical role in tumorgenesis. …”
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    Integrated analysis of promoter methylation and expression of telomere related genes in breast cancer
  7. 1627
    “…Cancer cells can use a telomerase-independent mechanism, known as alternative lengthening of telomeres (ALT), to elongate their telomeres. General control non-derepressible 5 (GCN5) and P300/CBP-associated factor (PCAF) are two homologous acetyltransferases that are mutually exclusive subunits in SAGA-like complexes. …”
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    Opposite effects of GCN5 and PCAF knockdowns on the alternative mechanism of telomere maintenance
  8. 1628
    “…Further studies show that Δ1a can discriminate human telomeric G-quadruplex from other telomeric G-quadruplexes.…”
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    Chiral metallohelices enantioselectively target hybrid human telomeric G-quadruplex DNA
  9. 1629
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    Erratum to: Telomere shortening and accelerated aging in COPD: findings from the BODE cohort
  10. 1630
    “…CONTEXT: Chronic psychological stress has been associated with shorter telomeres, but the underlying mechanisms are poorly understood. …”
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    The Longitudinal Relationship Between Cortisol Responses to Mental Stress and Leukocyte Telomere Attrition
  11. 1631
    “…Further, longitudinal assessment in preterm infants who had telomere length measurements available at both birth and term age (n = 5) suggests that telomere attrition rate is negatively correlated with increasing gestational age. …”
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    Preterm infants have significantly longer telomeres than their term born counterparts
  12. 1632
    “…BACKGROUND: Schizosaccharomyces pombe cells lacking the catalytic subunit of telomerase (encoded by trt1(+)) lose telomeric DNA and enter crisis, but rare survivors arise with either circular or linear chromosomes. …”
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    Global expression changes resulting from loss of telomeric DNA in fission yeast
  13. 1633
    “…The ends of linear chromosomes are capped by protein–DNA complexes termed telomeres. Telomere repeat binding factors 1 and 2 (TRF1 and TRF2) bind specifically to duplex telomeric DNA and are critical components of functional telomeres. …”
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    Oxidative damage in telomeric DNA disrupts recognition by TRF1 and TRF2
  14. 1634
    “…Functional telomeres are critically important to eukaryotic genetic stability. …”
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    Systematic Analysis of the DNA Damage Response Network in Telomere Defective Budding Yeast
  15. 1635
    “…Length of the telomere (TL), a structure at the tip of chromosome that protects and ensures stability, is determined by multi-protein complexes such as telosome/shelterin and telomerase. …”
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    Telomere length regulation through epidermal growth factor receptor signaling in cancer
  16. 1636
    “…Telomeres in human fibroblasts shorten progressively during in vitro culturing and trigger replicative senescence. …”
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    Telomere dynamics in a lizard with morph‐specific reproductive investment and self‐maintenance
  17. 1637
    “…The Telomeric Repeat-containing RNAs (TERRA) participate in the homeostasis of telomeres in higher eukaryotes. …”
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    Evidence for regulated expression of Telomeric Repeat-containing RNAs (TERRA) in parasitic trypanosomatids
  18. 1638
    “…Herein, we assessed the influence of environmental exposure on telomere length (TL) in both leukocytes (LTL) and sperm cells (STL). …”
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    Effects of Highly Polluted Environment on Sperm Telomere Length: A Pilot Study
  19. 1639
    “…Telomere length (TL) represents a promising biomarker of overall physiological state and of past environmental experiences, which could help us understand the drivers of life-history variation in natural populations. …”
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    Age-dependent associations between telomere length and environmental conditions in roe deer
  20. 1640
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    TRF2 Recruits RTEL1 to Telomeres in S Phase to Promote T-Loop Unwinding
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