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Mostrando 1,661 - 1,680 Resultados de 8,819 Para Buscar 'Telonero~', tiempo de consulta: 5.88s Limitar resultados
  1. 1661
    “…Telomere length (TL) comparisons from different methods are challenging due to differences in laboratory techniques and data configuration. …”
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    Telomere Length Calibration from qPCR Measurement: Limitations of Current Method
  2. 1662
    “…Replication-based telomere shortening during lifetime is species- and tissue-specific, however, its impact on healthy aging is unclear. …”
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    Cell cycle-dependent and -independent telomere shortening accompanies murine brain aging
  3. 1663
    “…Aging is a complex process involving declines in various cellular and physical functionalities, including regenerative ability. Telomere maintenance is thought to be necessary for regeneration, and telomere attrition is one mechanism that contributes to aging. …”
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    Telomere maintenance during anterior regeneration and aging in the freshwater annelid Aeolosoma viride
  4. 1664
    “…BACKGROUND: Newborn telomere length (TL) is considered a potential marker for future disease and lifelong health, but few epidemiological studies have examined the determinants of TL in early life. …”
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    Prenatal cadmium exposure is associated with shorter leukocyte telomere length in Chinese newborns
  5. 1665
    “…Alternative lengthening of telomeres (ALT) is a telomerase-independent but recombination-dependent pathway that maintains telomeres. …”
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    Alternative Lengthening of Telomeres through Two Distinct Break-Induced Replication Pathways
  6. 1666
    “…Vertebrate telomeres usually consist of hexameric TTAGGG repeats, however, in cells that use the alternative lengthening of telomeres (ALT) mechanism, variant repeat sequences are interspersed throughout telomeres. …”
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    ZBTB10 binds the telomeric variant repeat TTGGGG and interacts with TRF2
  7. 1667
    “…In addition, recent excessive oxidative stress can affect sperm telomere length and integrity of sperm DNA. Therefore, we assessed sperm telomere length as a potential marker of paternal genome integrity and leukocyte telomere length as an internal control (real-time PCR), along with sperm chromatin status (TUNEL and chromomycin A3 assay), and lipid peroxidation (Bodipy probe) in 18 infertile men with grade II or III varicocele, and 20 fertile men. …”
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    Reduced sperm telomere length in individuals with varicocele is associated with reduced genomic integrity
  8. 1668
    “…The qPCR method provides an inexpensive, rapid method for estimating relative telomere length across a set of biological samples. …”
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    Consequences of measurement error in qPCR telomere data: A simulation study
  9. 1669
    “…Telomere erosion, dysfunction, and fusion can lead to a state of cellular crisis characterized by large-scale genome instability. …”
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    Chromothripsis during telomere crisis is independent of NHEJ, and consistent with a replicative origin
  10. 1670
    “…However, the effects of short telomeres in very low proliferative tissues such as the brain have not been thoroughly investigated. …”
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    Telomerase gene therapy ameliorates the effects of neurodegeneration associated to short telomeres in mice
  11. 1671
    “…Telomeres are DNA-tandem repeats situated at the ends of chromosomes and are responsible for genome stabilization. …”
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    Leucocyte Telomere Length and Glucose Tolerance Status in Mixed-Ancestry South Africans
  12. 1672
    “…Therefore, telomeres are considered potential anti‐cancer targets and, to date, most of the studies have focused on telomerase inhibition. …”
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    Inhibiting TRF1 upstream signaling pathways to target telomeres in cancer cells
  13. 1673
    “…Telomeres are distal chromosome regions associated with specific protein complexes that protect the chromosome against degradation and aberrations. …”
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    The Role of Telomerase and Telomeres in Interstitial Lung Diseases: From Molecules to Clinical Implications
  14. 1674
    “…Telomere length has been accepted widely as a biomarker of aging. …”
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    Exploring the Relationship of Relative Telomere Length and the Epigenetic Clock in the LipidCardio Cohort
  15. 1675
    “…However, we still know little about the mechanisms that mediate these relationships. Telomere shortening is one possibility. Telomeres are long sequences of DNA that protect the ends of chromosomes. …”
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    The environmental and genetic determinants of chick telomere length in Tree Swallows (Tachycineta bicolor)
  16. 1676
    “…Cancer cells need to acquire telomere maintenance mechanisms in order to counteract progressive telomere shortening due to multiple rounds of replication. …”
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    X-rays Activate Telomeric Homologous Recombination Mediated Repair in Primary Cells
  17. 1677
    “…Telomere length is considered to be a biomarker of biological aging and age-related disease. …”
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    Shortening telomere is associated with subclinical atherosclerosis biomarker in omnivorous but not in vegetarian healthy men
  18. 1678
    “…ARID1A promotes the expression of cohesin subunit STAG1 that is specifically required for telomere cohesion. ARID1A inactivation causes telomere damage that can be rescued by STAG1 expression. …”
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    ARID1A promotes genomic stability through protecting telomere cohesion
  19. 1679
    “…BACKGROUND: Telomeres, repetitive DNA capping ends of eukaryotic chromosomes, are important in the maintenance of genomic integrity. …”
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    Relationship of telomere length in colorectal cancer patients with cancer phenotype and patient prognosis
  20. 1680
    “…However, its impact on infant’s biology, in particular on telomere length (TL) is unknown. The aim of this study was to examine the association between IPV against women before childbirth and cord blood TL in their newborn. …”
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    The association between intimate partner violence against women and newborn telomere length
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