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  1. 1741
    “…Serum levels of 10 pro and anti-inflammatory cytokines and two antioxidant enzymes were compared in age and sport intensity groups and telomere lengths were measured in their respective blood samples. …”
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    Age and Sport Intensity-Dependent Changes in Cytokines and Telomere Length in Elite Athletes
  2. 1742
    “…Protecting telomere from the DNA damage response is essential to avoid the entry into cellular senescence and organismal aging. …”
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    Multifunctionality of the Telomere-Capping Shelterin Complex Explained by Variations in Its Protein Composition
  3. 1743
    “…However, limited information is available on the effect of cART on telomere length (TL) in microglia. Although it is well established that telomere shortening induces cell senescence and contributes to the development of age-related neuro-pathologies, the effect of HIV-Tat on telomere length in human microglial cells and its potential contribution to HAND are not well understood. …”
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    Telomere Length Shortening in Microglia: Implication for Accelerated Senescence and Neurocognitive Deficits in HIV
  4. 1744
    “…Telomerase/telomere-targeting therapy is a potentially promising approach for cancer treatment because even transient telomere dysfunction can induce chromosomal instability (CIN) and may be a barrier to tumor growth. …”
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    Terpyridine platinum compounds induce telomere dysfunction and chromosome instability in cancer cells
  5. 1745
    “…OBJECTIVE: Telomere shortening has been seen in major psychiatric disorders, including major depressive disorder. …”
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    Significant Shortening of Leukocyte Telomere Length in Korean Patients with Bipolar Disorder 1
  6. 1746
    “…Background: To date, available data on premature aging in young HIV-infected adults are scarce and no reports offer comprehensive assessment of telomere shortening (TS) in relation to subclinical atherosclerosis (SCA). …”
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    Subclinical atherosclerosis and immune activation in young HIV-infected patients with telomere shortening
  7. 1747
    “…BACKGROUND: Leukocyte telomere length (LTL) has been revealed to be associated with aging-related diseases such as metabolic syndrome (MetS) and Type 2 diabetes mellitus (T2DM). …”
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    Association of leukocyte telomere length with metabolic syndrome in type 2 diabetes mellitus
  8. 1748
    “…OBJECTIVES: Telomeres are structures at the extremity of chromosomes that prevents genomic instability, and its shortening seems to be a hallmark of cellular aging. …”
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    Telomere shortening in late‐life depression: A potential marker of depression severity
  9. 1749
    “…BACKGROUND: The comparative length of telomeres is considered to be related to diseases such as cancer, aging, and cardiovascular diseases. qPCR is currently one of the main methods for detecting telomere length. …”
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    A novel multiplex qPCR method for assessing the comparative lengths of telomeres
  10. 1750
    “…Human shelterin components POT1 and TPP1 form a stable heterodimer that protects telomere ends from ATR-dependent DNA damage responses and regulates telomerase-dependent telomere extension. …”
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    Distinct functions of POT1 proteins contribute to the regulation of telomerase recruitment to telomeres
  11. 1751
    “…We previously observed an unexpected proliferation-independent telomere shortening in cardiomyocytes of a DMD mouse model. …”
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    Increased tissue stiffness triggers contractile dysfunction and telomere shortening in dystrophic cardiomyocytes
  12. 1752
    “…This study determined whether measures of adult body weight, length and relative telomere length were related to lifespan. Skin tissue samples (n = 338) were obtained from 23 marine mammal species, including four Mysticeti, 19 Odontoceti and one dugong species, and the DNA extracted to measure relative telomere length using real-time PCR. …”
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    Life Expectancy in Marine Mammals Is Unrelated to Telomere Length but Is Associated With Body Size
  13. 1753
    “…Objective: This two-sample Mendelian randomization (MR) study aimed to examine the potential causal association of telomere length (TL) with the risk of osteoarthritis (OA). …”
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    Genetically Predicted Longer Telomere Length May Reduce Risk of Hip Osteoarthritis
  14. 1754
    “…In cancer, telomere maintenance is critical for the development of replicative immortality. …”
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    Integrated evaluation of telomerase activation and telomere maintenance across cancer cell lines
  15. 1755
    “…In vertebrates the Shelterin protein complex protects telomeric DNA ends, thereby contributing to the maintenance of genome integrity. …”
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    Evolutionary mode for the functional preservation of fast-evolving Drosophila telomere capping proteins
  16. 1756
    “…Loss of telomeric DNA leads to telomere uncapping, which triggers a persistent, p53-centric DNA damage response that sustains a stable senescence-associated proliferation arrest. …”
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    Homologous recombination-mediated irreversible genome damage underlies telomere-induced senescence
  17. 1757
    “…Multiple risk factors of stroke are associated with telomere length shortening. Although leukocyte telomere length (LTL) is shorter in patients with stroke, the heterogeneity is high. …”
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    Gender Difference in Associations Between Telomere Length and Risk Factors in Patients With Stroke
  18. 1758
    “…Although the roles of telomeres and oxidative stress in ischaemic cardiomyopathy (ICM) are known, mechanisms of telomere homeostasis and their relationship with oxidative stress are incompletely understood. …”
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    Relationships of Telomere Homeostasis with Oxidative Stress and Cardiac Dysfunction in Human Ischaemic Hearts
  19. 1759
    “…BACKGROUND: Observational studies have suggested that telomere length is associated with amyotrophic lateral sclerosis (ALS). …”
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    Leukocyte telomere length and amyotrophic lateral sclerosis: a Mendelian randomization study
  20. 1760
    “…Oxidative stress caused by excess reactive oxygen species (ROS) accelerates telomere erosion and mitochondrial injury, leading to impaired cellular functions and cell death. …”
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    Selective oxidative stress induces dual damage to telomeres and mitochondria in human T cells
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