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Mostrando 1,821 - 1,840 Resultados de 8,819 Para Buscar 'Telonero~', tiempo de consulta: 3.75s Limitar resultados
  1. 1821
    “…Objective: To elucidate the potential causality of leukocyte telomere length (LTL) with immune-mediated inflammatory diseases (IMIDs), we conducted a Mendelian randomization (MR) study. …”
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    Immune-mediated inflammatory diseases and leukocyte telomere length: A Mendelian randomization study
  2. 1822
    “…Telomeres, at the ends of chromosomes, protect chromosomes from fusion and preserve genomic stability. …”
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    Critically short telomeres derepress retrotransposons to promote genome instability in embryonic stem cells
  3. 1823
    “…Although HCC has been associated with the telomere length (TL), the causal relationship between them is not well understood. …”
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    Association between telomere length and hepatocellular carcinoma risk: A Mendelian randomization study
  4. 1824
    “…BACKGROUND: Due to the inadequacy of published evidence, association of telomere length (TL), obesity and tobacco smoking with idiopathic pulmonary fibrosis (IPF) remains unclear. …”
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    Genetic association of telomere length, obesity and tobacoo smoking with idiopathic pulmonary fibrosis risk
  5. 1825
    “…Correlations were reported between sperm telomere length (STL) and male fertility, sperm DNA fragmentation, and oxidation. …”
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    Freezing Does Not Alter Sperm Telomere Length despite Increasing DNA Oxidation and Fragmentation
  6. 1826
    “…Here, we studied the possibility of manipulating the secondary structure of a human telomeric G4 sequence through the interaction with two photosensitive ligands, DTE and TMPyP4, whose response to visible light is different. …”
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    Stability of Human Telomeric G-Quadruplexes Complexed with Photosensitive Ligands and Irradiated with Visible Light
  7. 1827
    “…Telomere shortening, a marker of cellular aging, has been linked to hospitalization and the severity of COVID-19. …”
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    Is COVID-19 severity associated with telomere length? A systematic review and meta-analysis
  8. 1828
    “…Telomere length maintenance is crucial to cancer cell immortality. …”
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    Hyperextended telomeres promote formation of C-circle DNA in telomerase positive human cells
  9. 1829
    “…TERF2/TRF2 is a pleiotropic telomeric protein that plays a crucial role in tumor formation and progression through several telomere-dependent and -independent mechanisms. …”
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    The telomeric protein TERF2/TRF2 impairs HMGB1-driven autophagy
  10. 1830
    “…Telomeres are the terminal regions of chromosomes that ensure their stability while cell division. …”
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    Compilation and functional classification of telomere length-associated genes in humans and other animal species
  11. 1831
    por Denham, Joshua
    Publicado 2023
    “…Telomerase preserves genomic integrity by maintaining and protecting the telomeres. Seminal findings from 1985 revealed the canonical role of telomerase and motivated investigations into potential therapeutic strategies to combat one of the hallmarks of ageing—telomere attrition. …”
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    Canonical and extra‐telomeric functions of telomerase: Implications for healthy ageing conferred by endurance training
  12. 1832
    “…A negative correlation was observed between telomere length and cortisol (stress biomarker), whereas a positive correlation was found between telomere length and well-being. …”
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    Impact of Heartfulness meditation practice on anxiety, perceived stress, well-being, and telomere length
  13. 1833
    “…METHODS: We first recognized differentially expressed telomere-related genes (TRGs) and accordingly developed a risk model by univariate and multivariate Cox analysis. …”
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    Construction of a telomere-related gene signature to predict prognosis and immune landscape for glioma
  14. 1834
    “…Here, we utilize previously published data documenting the loss of telomeric DNA repeats in granulocytes, to draw inferences about HSC division rates, the timing of major changes in those rates, as well as lifetime division totals. …”
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    Predicting the number of lifetime divisions for hematopoietic stem cells from telomere length measurements
  15. 1835
    por Wan, Bangbei, Lu, Likui, Lv, Cai
    Publicado 2023
    “…BACKGROUND: Leukocyte telomere length (LTL) is related to prostate cancer (PCa). …”
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    Mendelian randomization study on the causal relationship between leukocyte telomere length and prostate cancer
  16. 1836
    “…BACKGROUND: Telomeres are strongly associated with cancer, as their shortening over time is associated with an increased risk of tumor growth and progression. …”
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    Telomere-Associated Gene Signatures Correlate with Prognosis, Tumor Microenvironment, and Chemosensitivity in Breast Cancer
  17. 1837
    “…SIMPLE SUMMARY: Telomeres are essential to prevent telomere end fusions that cause the formation of dicentric chromosomes and nucleoplasmic bridges (NPBs) which in turn induce chromosomal instability, cancer initiation and progression. …”
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    The Relationship between Telomere Length and Nucleoplasmic Bridges and Severity of Disease in Prostate Cancer Patients
  18. 1838
    “…Premature telomere shortening is a known factor correlated to idiopathic pulmonary fibrosis (IPF) occurrence, which is a chronic, progressive, age-related disease with high mortality. …”
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    UBQLN1 deficiency mediates telomere shortening and IPF through interacting with RPA1
  19. 1839
    “…Zinc finger and SCAN domain-containing 4 (ZSCAN4), a DNA-binding protein, maintains telomere length and plays a key role in critical aspects of mouse embryonic stem cells, including maintaining genomic stability and defying cellular senescence. …”
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    ZSCAN4 Regulates Zygotic Genome Activation and Telomere Elongation in Porcine Parthenogenetic Embryos
  20. 1840
    “…Background: Leukocyte telomere length and hepatic disorders have been linked in various research studies, although their causative association has not been clarified. …”
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    Causal relationships between telomere length and liver disease: a Mendelian randomization study
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