Mostrando 1,841 - 1,860 Resultados de 8,819 Para Buscar 'Telonero~', tiempo de consulta: 5.55s Limitar resultados
  1. 1841
    “…The telomeric noncoding RNA TERRA is a key component of telomeres and it is widely expressed in normal as well as cancer cells. …”
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  2. 1842
    por Cao, Zhi, Hou, Yabing, Xu, Chenjie
    Publicado 2023
    “…BACKGROUND: The evidence regarding the association between leucocyte telomere length (LTL) and brain health is sparse and inconclusive. …”
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  3. 1843
  4. 1844
  5. 1845
    “…In this study, we investigated whether the supplementation of standardized Bacopa monnieri extract (CDRI-08/BME) or l-Carnosine (L-C) to the mother exposed to social stress during gestation modify the effect on their offspring's neurobehaviour, antioxidant defence gene expression, telomere length, and telomere biology. To test this, timed pregnant rats were subjected to social stress during the gestational day (GD) 16–18. …”
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  6. 1846
    “…One of the main triggers of replicative senescence is telomere shortening and/or its dysfunction and, therefore, a deep understanding of the molecular determinants is crucial. …”
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  7. 1847
    por Chi, Zhenfei, Bai, Xuesong, Zhang, Zhe
    Publicado 2023
    “…As a marker of cellular and biological aging, we employed 15 single-nucleotide polymorphisms as instrumental variables for leukocyte telomere length (LTL) as exposure and a GWAS for constipation in the Finnish database as an outcome. …”
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  8. 1848
    por Shin, Yun-A, Kim, Jae-Hyun
    Publicado 2023
    “…BACKGROUND: This study investigates differences in telomere length according to obesity, cardiovascular disease (CVD) risk factors, and fitness level in South Korean males. …”
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  9. 1849
  10. 1850
  11. 1851
    “…Telomerase solves the end-replication problem by adding G-rich telomeric repeats to the 3ʹ ends of telomeres(1). We report a second end-replication problem affecting the C-rich telomeric repeat strand that is solved by fill-in synthesis by CST–Polymeraseα(Polα)-primase. …”
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  12. 1852
    “…OBJECTIVE: Observational studies have reported bidirectional associations between metabolic syndrome (MetS) traits and short leukocyte telomere length (LTL), a TL marker in somatic tissues and a proposed risk factor for age‐related degenerative diseases. …”
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  13. 1853
    por Luo, Xinxin, Ruan, Zhichao, Liu, Ling
    Publicado 2023
    “…OBJECTIVE: Observational studies have suggested a link between telomere length (TL) and epilepsy, but the direction of the effect and whether it is causal or not is still being debated. …”
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  14. 1854
    por Hartig, Jörg S., Kool, Eric T.
    Publicado 2005
    “…Repeating DNA sequences, such as telomeres, centromeres, and micro- and mini-satellites, comprise 50% of the genome and play important roles in regulatory and pathogenic mechanisms. …”
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  15. 1855
    por Tsolou, Avgi, Lydall, David
    Publicado 2007
    “…In this study, we addressed the role of Mrc1 at uncapped telomeres. Our experiments show that Mrc1 contributes to the vitality of both cdc13-1 and yku70Δ telomere capping mutants. …”
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  16. 1856
    “…To study the effect of continued telomere shortening on chromosome stability, we have analyzed the telomere length of two individual chromosomes (chromosomes 2 and 11) in fibroblasts derived from wild-type mice and from mice lacking the mouse telomerase RNA (mTER) gene using quantitative fluorescence in situ hybridization. …”
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  17. 1857
    “…Telomeres share the ability to silence nearby transcription with heterochromatin, but the requirement of heterochromatin proteins for most telomere functions is unknown. …”
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  18. 1858
  19. 1859
  20. 1860
    “…These data indicate that some of the genomic instability in head and neck tumours is initiated by telomere dysfunction, leading to the formation of dicentric chromosomes. …”
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