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Mostrando 1,881 - 1,900 Resultados de 8,819 Para Buscar 'Telonero~', tiempo de consulta: 9.08s Limitar resultados
  1. 1881
    “…Removal of the conserved telomere protein, Pot1, confers the immediate loss of fission yeast telomeres. …”
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    Pot1 inactivation leads to rampant telomere resection and loss in one cell cycle
  2. 1882
    “…BACKGROUND: Short interstitial telomere motifs (telo boxes) are short sequences identical to plant telomere repeat units. …”
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    Distribution of short interstitial telomere motifs in two plant genomes: putative origin and function
  3. 1883
    “…Telomeres are specialized chromatin structures at the end of chromosomes. …”
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    Zebrafish as a Model System to Study the Physiological Function of Telomeric Protein TPP1
  4. 1884
    “…RESULTS: Here we employed high-resolution multi-color fluorescence in situ hybridization (FISH) to show integration of MDV at the telomeres of chicken chromosomes. Cytogenomic mapping of the chromosomal integrations allowed us to examine the clonal relationships among lymphomas within individuals, whereas analysis of tumors from multiple individuals indicated the potential for chromosomal preferences. …”
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    Chromosomal integration of an avian oncogenic herpesvirus reveals telomeric preferences and evidence for lymphoma clonality
  5. 1885
    “…Gene-silencing mechanisms are being shown to be associated with an increasing number of fungal developmental processes. Telomere position effect (TPE) is a eukaryotic phenomenon resulting in gene repression in areas immediately adjacent to telomere caps. …”
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    Telomere position effect is regulated by heterochromatin-associated proteins and NkuA in Aspergillus nidulans
  6. 1886
    “…The telomeric protein such as TRF2 which is an important target for anticancer therapy against human breast cancer was extensively studied along with proteins involved in proper functioning of telomeres. …”
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    Chalcone-imidazolone conjugates induce apoptosis through DNA damage pathway by affecting telomeres
  7. 1887
    “…Here, we analyzed the influence of telomere shortening (a basic mechanism of cellular aging) on homeostasis and regenerative reserve in response to chemical induced injury of the OE in late generation telomere knockout mice (G3 mTerc(−/−)) with short telomeres compared to wild type mice (mTerc(+/+)) with long telomeres. …”
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    Telomere Shortening Impairs Regeneration of the Olfactory Epithelium in Response to Injury but Not Under Homeostatic Conditions
  8. 1888
    “…INTRODUCTION: Telomere length plays important roles in maintaining genome stability and regulating cell replication and death. …”
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    Telomerase expression and telomere length in breast cancer and their associations with adjuvant treatment and disease outcome
  9. 1889
    “…This RNP minimally contains a reverse transcriptase protein subunit (TERT) that catalyzes telomeric DNA synthesis and an RNA subunit (TER) that has templating, architectural and protein-scaffolding roles. …”
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    The RNA accordion model for template positioning by telomerase RNA during telomeric DNA synthesis
  10. 1890
    “…In telomerase-deficient yeast cells, like equivalent mammalian cells, telomeres shorten over many generations until a period of senescence/crisis is reached. …”
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    Genome-Wide Analysis to Identify Pathways Affecting Telomere-Initiated Senescence in Budding Yeast
  11. 1891
    “…In addition, embryonic exposure to cort resulted in higher levels of reactive oxygen metabolites and an over-representation of short telomeres compared with the control birds. In many species, individuals with higher levels of oxidative stress and shorter telomeres have the poorest survival prospects. …”
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    Embryonic exposure to corticosterone modifies the juvenile stress response, oxidative stress and telomere length
  12. 1892
    “…The CTC1/STN1/TEN1 (CST) complex is an essential constituent of plant and vertebrate telomeres. Here we show that CST and ATR (ataxia telangiectasia mutated [ATM] and Rad3-related) act synergistically to maintain telomere length and genome stability in Arabidopsis. …”
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    ATR cooperates with CTC1 and STN1 to maintain telomeres and genome integrity in Arabidopsis
  13. 1893
    “…Telomeric and adjacent subtelomeric heterochromatin pose significant challenges to the DNA replication machinery. …”
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    Human telomeres replicate using chromosome-specific, rather than universal, replication programs
  14. 1894
    “…The bouquet stage, where telomeres have formed a transient single cluster early in meiotic prophase, and telomere-promoted rapid meiotic prophase chromosome movements (RPMs) are prominent temporal correlates of pairing and synapsis. …”
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    Meiotic Chromosome Pairing Is Promoted by Telomere-Led Chromosome Movements Independent of Bouquet Formation
  15. 1895
    “…Continuously dividing cells must be protected from telomeric and nontelomeric DNA damage in order to maintain their proliferative potential. …”
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    Nucleostemin prevents telomere damage by promoting PML-IV recruitment to SUMOylated TRF1
  16. 1896
    por Pfeiffer, Verena, Lingner, Joachim
    Publicado 2012
    “…The long noncoding telomeric repeat containing RNA (TERRA) is expressed at chromosome ends. …”
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    TERRA Promotes Telomere Shortening through Exonuclease 1–Mediated Resection of Chromosome Ends
  17. 1897
    “…In normal human somatic cells, telomere dysfunction causes cellular senescence, a stable proliferative arrest with tumour suppressing properties. …”
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    Oncogene-induced telomere dysfunction enforces cellular senescence in human cancer precursor lesions
  18. 1898
    “…Here we review the case of such a new gene, which involves a telomere-capping gene family in Drosophila. hiphop and its testis-specific paralog K81 are critical for the protection of chromosome ends in somatic cells and male gametes, respectively. …”
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    Repeated Evolution of Testis-Specific New Genes: The Case of Telomere-Capping Genes in Drosophila
  19. 1899
    “…We found mixed evidence for an association between SES and telomere length. In 35-year-olds, many of the education and childhood SES measures were associated with telomere length, i.e. those in poorer circumstances had shorter telomeres, as was intergenerational social mobility, but not accumulated disadvantage. …”
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    Is Telomere Length Socially Patterned? Evidence from the West of Scotland Twenty-07 Study
  20. 1900
    por Luke-Glaser, Sarah, Luke, Brian
    Publicado 2012
    “…In some rare instances telomeres engage in Break-Induced Replication (BIR), a type of HR, in order to maintain telomere length in the absence of the enzyme telomerase. …”
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    The Mph1 Helicase Can Promote Telomere Uncapping and Premature Senescence in Budding Yeast
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