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Mostrando 1,921 - 1,940 Resultados de 8,819 Para Buscar 'Telonero~', tiempo de consulta: 4.90s Limitar resultados
  1. 1921
    “…We describe here studies designed to determine how PEG and other co-solutes affect the conformation of the human telomeric quadruplex. Osmotic stress studies using acetonitrile and ethylene glycol show that conversion of the ‘hybrid’ conformation to an all-parallel ‘propeller’ conformation is accompanied by the release of about 17 water molecules per quadruplex and is energetically unfavorable in pure aqueous solutions. …”
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    Polyethylene glycol binding alters human telomere G-quadruplex structure by conformational selection
  2. 1922
    “…Telomere length varies greatly among individuals of the same age, and is heritable. …”
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    QTL mapping of leukocyte telomere length in American Indians: The Strong Heart Family Study
  3. 1923
    “…This is the first evidence of the insect-type TTAGG telomeric repeats in Heteroptera.…”
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    The first finding of (TTAGG)(n) telomeric repeat in chromosomes of true bugs (Heteroptera, Belostomatidae)
  4. 1924
    “…BACKGROUND: Several epidemiological studies have examined the association between shortened telomere length and type 2 diabetes mellitus (T2DM), while the results remained conflicting. …”
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    Association between Telomere Length and Type 2 Diabetes Mellitus: A Meta-Analysis
  5. 1925
    “…Telomeres are actively transcribed into telomeric repeat-containing RNA (TERRA), which has been implicated in the regulation of telomere length and heterochromatin formation. …”
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    Quantitative interaction screen of telomeric repeat-containing RNA reveals novel TERRA regulators
  6. 1926
    “…RESULTS: In this study we have shown that a telomeric single stranded specific PNA probe is able to bind to its target without heat denaturing of the DNA and without formamide. …”
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    Direct DNA and PNA probe binding to telomeric regions without classical in situ hybridization
  7. 1927
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    Correction: Structure and Stability of Human Telomeric G-Quadruplex with Preclinical 9-Amino Acridines
  8. 1928
    “…We evaluated different epigenetic regulators for their ability to protect transgene expression at telomeres, which are commonly associated to low or inconsistent expression because of their repressive chromatin environment. …”
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    Epigenetic regulatory elements associate with specific histone modifications to prevent silencing of telomeric genes
  9. 1929
    “…DNA was extracted from the balloon cytology cells, and telomere length was measured by quantitative PCR. A receiver operating characteristic (ROC) curve was plotted for telomere length as a diagnostic marker for high-grade dysplasia. …”
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    Measuring telomere length for the early detection of precursor lesions of esophageal squamous cell carcinoma
  10. 1930
    “…BACKGROUND: Human telomeres, tandem repeats of TTAGGG nucleotides at the ends of chromosomes, are essential for maintaining genomic integrity and stability. …”
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    Telomere Length in Peripheral Blood Leukocytes Is Associated with Risk of Colorectal Cancer in Chinese Population
  11. 1931
    “…Telomeres and telomerase have important biological functions and can protect chromosome ends. …”
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    Sex- and season-dependent differences in telomere length and telomerase activity in the leaves of ash and willow
  12. 1932
    “…The goal of this study is to investigate the association between oxidative stress and telomere length shortening in the comorbid depression and diabetes. …”
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    Leucocyte Telomere Shortening in relation to Newly Diagnosed Type 2 Diabetic Patients with Depression
  13. 1933
    “…Extensive studies have established most of the genetic basis of the DNA damage checkpoint and uncovered its different functions in cell cycle regulation, DNA replication and repair, and telomere maintenance. However, major questions concerning the regulation and functions of the DNA damage checkpoint remain to be answered. …”
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    Preserving Yeast Genetic Heritage through DNA Damage Checkpoint Regulation and Telomere Maintenance
  14. 1934
    Publicado 2014
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    Correction: A Human Artificial Chromosome Recapitulates the Metabolism of Native Telomeres in Mammalian Cells
  15. 1935
    “…One such role is the attachment of telomeres to trans-nuclear envelope protein complexes that connect telomeres to motor proteins in the cytoplasm. …”
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    Mouse CCDC79 (TERB1) is a meiosis-specific telomere associated protein
  16. 1936
    “…Previous studies have demonstrated that telomere length is a hallmark of radiosensitivity. …”
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    CTC1 increases the radioresistance of human melanoma cells by inhibiting telomere shortening and apoptosis
  17. 1937
    “…Telomeric DNA can form duplex regions or single-stranded loops that bind multiple proteins, preventing it from being processed as a DNA repair intermediate. …”
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    The effect of Pot1 binding on the repair of thymine analogs in a telomeric DNA sequence
  18. 1938
    “…CONTEXT: Telomere maintenance via telomerase activation and the alternative lengthening of telomeres (ALT) mechanism was assessed in medullary thyroid carcinoma. …”
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    Telomerase-Dependent and Independent Telomere Maintenance and its Clinical Implications in Medullary Thyroid Carcinoma
  19. 1939
    “…Telomerase-negative yeasts survive via one of the two Rad52-dependent recombination pathways, which have distinct genetic requirements. Although the telomere pattern of type I and type II survivors is well characterized, the mechanistic details of short telomere rearrangement into highly evolved pattern observed in survivors are still missing. …”
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    Rad59-Facilitated Acquisition of Y′ Elements by Short Telomeres Delays the Onset of Senescence
  20. 1940
    “…Objective To examine whether adherence to the Mediterranean diet was associated with longer telomere length, a biomarker of aging. Design Population based cohort study. …”
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    Mediterranean diet and telomere length in Nurses’ Health Study: population based cohort study
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