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  1. 1961
    “…Here we examine WRN's role in telomeric maintenance, by comparing its action on a variety of DNA structures without or with telomeric sequences. …”
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    The DNA structure and sequence preferences of WRN underlie its function in telomeric recombination events
  2. 1962
    “…We found that telomere-associated DNA damage foci increase in small airway epithelial cells from patients with COPD, without significant telomere shortening detected. …”
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    DNA damage response at telomeres contributes to lung aging and chronic obstructive pulmonary disease
  3. 1963
    “…BACKGROUND: Subjects born preterm have an increased risk for age-associated diseases, such as cardiovascular disease in later life, but the underlying causes are largely unknown. Shorter leukocyte telomere length (LTL), a marker of biological age, is associated with increased risk of cardiovascular disease. …”
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    Leukocyte Telomere Length in Young Adults Born Preterm: Support for Accelerated Biological Ageing
  4. 1964
    “…Telomeres are located at chromosome ends and their length (TL) has been associated with aging and human diseases such as cancer. …”
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    Preanalytical Conditions and DNA Isolation Methods Affect Telomere Length Quantification in Whole Blood
  5. 1965
    “…Dyskeratosis congenita (DC) is an inherited BMF syndrome characterized by the presence of short telomeres, mucocutaneous abnormalities, and cancer predisposition. …”
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    Disrupted lymphocyte homeostasis in hepatitis‐associated acquired aplastic anemia is associated with short telomeres
  6. 1966
    por Bateson, Melissa
    Publicado 2015
    “…Evidence from non‐human animals suggests that despite some specific differences in telomere biology, stress‐induced telomere attrition is a robust phenomenon, occurring in a range of species including mice and chickens. …”
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    Cumulative stress in research animals: Telomere attrition as a biomarker in a welfare context?
  7. 1967
    “…Telomere maintenance has emerged as an important molecular feature with impacts on adult glioma susceptibility and prognosis. …”
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    Longer genotypically-estimated leukocyte telomere length is associated with increased adult glioma risk
  8. 1968
    “…DNA G-hairpins are potential key structures participating in folding of human telomeric guanine quadruplexes (GQ). We examined their properties by standard MD simulations starting from the folded state and long T-REMD starting from the unfolded state, accumulating ∼130 μs of atomistic simulations. …”
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    Hairpins participating in folding of human telomeric sequence quadruplexes studied by standard and T-REMD simulations
  9. 1969
    “…SRSF11 also associates with telomeres through an interaction with TRF2, which facilitates translocation of telomerase to telomeres. …”
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    Involvement of SRSF11 in cell cycle-specific recruitment of telomerase to telomeres at nuclear speckles
  10. 1970
    “…Rap1-interacting factor 1 (Rif1) was originally identified in the budding yeast Saccharomyces cerevisiae as a telomere-binding protein that negatively regulates telomerase-mediated telomere elongation. …”
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    Rif1: A Conserved Regulator of DNA Replication and Repair Hijacked by Telomeres in Yeasts
  11. 1971
    “…Using the GMP-quadruplex, built by the stacking of G-quartets with no covalent linking between them, as the baseline, we report the liquid-crystalline phase behaviors of two other related G-quadruplexes: (i) the intramolecular parallel-stranded G-quadruplex formed by the 22-mer four-repeat human telomeric sequence AG(3)(TTAG(3))(3) and (ii) the intermolecular parallel-stranded G-quadruplex formed by the TG(4)T oligonucleotides. …”
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    X-ray characterization of mesophases of human telomeric G-quadruplexes and other DNA analogues
  12. 1972
    “…OBJECTIVES: To explore the association between plasma antioxidant status, marker of cellular ageing (leukocyte telomere length, LTL) and 10 years risk of IHD in patients with T2D. …”
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    Telomere length, antioxidant status and incidence of ischaemic heart disease in type 2 diabetes
  13. 1973
    por Hendrickson, Eric A, Baird, Duncan M
    Publicado 2015
    “…Telomere dysfunction and fusion play key roles in driving genomic instability and clonal evolution in many tumor types. …”
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    Alternative end joining, clonal evolution, and escape from a telomere-driven crisis
  14. 1974
    “…Here we show that HMGA2 localizes to mammalian telomeres and enhances telomere stability in cancer cells. …”
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    High Mobility Group A2 protects cancer cells against telomere dysfunction
  15. 1975
    por Shin, Yun-A, Lee, Kyoung-Young
    Publicado 2016
    “…The aim of this study was to determine whether there is an association between leukocyte telomere length (LTL), and estrogen level, oxidative stress, cardiovascular disease (CVD) risk factors, and cardiorespiratory fitness (CRF) in pre- and postmenopausal obese women. …”
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    Low estrogen levels and obesity are associated with shorter telomere lengths in pre- and postmenopausal women
  16. 1976
    “…The relative telomere length (RTL) was determined by q-PCR as the telomere to single copy gene (36B4) ratio normalized to a reference sample (K-562 DNA). …”
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    Telomere length shortening is associated with treatment-free remission in chronic myeloid leukemia patients
  17. 1977
    “…We induced palindrome formation by passaging cells lacking any form of telomere maintenance (telomerase and telomere recombination). …”
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    Telomere Dysfunction Triggers Palindrome Formation Independently of Double-Strand Break Repair Mechanisms
  18. 1978
    “…The analysis of individuals with telomere defects may shed light on the delicate interplay of factors controlling genome stability, premature aging, and cancer. …”
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    Mutations in STN1 cause Coats plus syndrome and are associated with genomic and telomere defects
  19. 1979
    “…Telomeres are DNA-protein structures at the ends of chromosomes. …”
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    Longitudinal decline of leukocyte telomere length in old age and the association with sex and genetic risk
  20. 1980
    “…We studied relative telomere length in a wild population of Seychelles warblers (Acrocephalus sechellensis) to assess the lifelong relationship between individual homozygosity, which reflects genome‐wide inbreeding in this species, and telomere length. …”
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    Telomere length reveals cumulative individual and transgenerational inbreeding effects in a passerine bird
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