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  1. 1
    por Schoeftner, Stefan, Blasco, Maria A
    Publicado 2009
    “…Protection of chromosome ends from DNA repair and degradation activities is mediated by specialized protein complexes bound to telomere repeats. Recently, it has become apparent that epigenetic regulation of the telomric chromatin template critically impacts on telomere function and telomere-length homeostasis from yeast to man. …”
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    A ‘higher order' of telomere regulation: telomere heterochromatin and telomeric RNAs
  2. 2
    por Li, Heng, Durbin, Richard
    Publicado 2023
    “…We focus on how to derive near telomere-to-telomere assemblies and discuss potential future developments.…”
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    Genome assembly in the telomere-to-telomere era
  3. 3
    por Brault, Marie Eve, Autexier, Chantal
    Publicado 2011
    “… Telomere maintenance is essential for cellular immortality, and most cancer cells maintain their telomeres through the enzyme telomerase. …”
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    Telomeric recombination induced by dysfunctional telomeres
  4. 4
    “…Telomeres are transcribed generating long non-coding RNAs known as TERRA. …”
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    Telomeric RNAs are essential to maintain telomeres
  5. 5
    “…To escape from the normal limits on proliferative potential, cancer cells must employ a means to counteract the gradual telomere attrition that accompanies semi-conservative DNA replication. …”
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    Alternative lengthening of telomeres: remodeling the telomere architecture
  6. 6
    por Martínez, Paula, Blasco, Maria A.
    Publicado 2017
    “…Telomeres, the protective ends of linear chromosomes, shorten throughout an individual’s lifetime. …”
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    Telomere-driven diseases and telomere-targeting therapies
  7. 7
    “…Telomeres are genomic complex at the end of chromosomes that protects the DNA and telomere length (TL) is related to several age-related diseases, lifespan, and cancer. …”
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    Exercise, Telomeres, and Cancer: “The Exercise-Telomere Hypothesis”
  8. 8
    “…Telomere length, a complex hereditary trait, is associated with aging and age-related diseases. …”
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    Telomeres and Telomere Length: A General Overview
  9. 9
    “…Telomere shortening can cause detrimental diseases and contribute to aging. …”
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    The human telomeric proteome during telomere replication
  10. 10
    “…SIMPLE SUMMARY: Alternative lengthing of telomere (ALT) is an important mechanism for maintaining telomere length and cell proliferation in telomerase-negative tumor cells. …”
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    Alternative Lengthening of Telomeres and Mediated Telomere Synthesis
  11. 11
    “…While most of the genome has been assembled, the currently available genome assembly is not a completed telomere-to-telomere assembly. Here, we used Oxford Nanopore long reads to build a telomere-to-telomere genome for Phaeodactylum tricornutum. …”
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    Telomere-to-telomere genome assembly of Phaeodactylum tricornutum
  12. 12
    “…Although the impact of telomeres on physiology stands well established, a question remains: how do telomeres impact cellular functions at a molecular level? …”
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    Telomeres expand sphere of influence: emerging molecular impact of telomeres in non-telomeric functions
  13. 13
    “…Here, we report the first telomere-to-telomere genome assembly of matsutake (Tricholoma matsutake), which consists of 13 sequences (spanning 161.0 Mb) and a 76 kb circular mitochondrial genome. …”
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    Telomere-to-telomere genome assembly of matsutake (Tricholoma matsutake)
  14. 14
    “…A complete telomere-to-telomere (T2T) finished genome has been the long pursuit of genomic research. …”
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    A complete telomere-to-telomere assembly of the maize genome
  15. 15
    por Isken, Olaf, Maquat, Lynne E
    Publicado 2009
    “…Telomeres protect linear chromosome ends from being recognized and processed as double-strand breaks by DNA repair activities. …”
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    Telomeric RNAs as a novel player in telomeric integrity
  16. 16
    “…Alternative lengthening of telomeres (ALT) is one of the two known telomere length maintenance mechanisms that are essential for the unlimited proliferation potential of cancer cells. …”
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    Detection of alternative lengthening of telomeres by telomere quantitative PCR
  17. 17
    por Massey, Dashiell J., Koren, Amnon
    Publicado 2022
    “…Here, we report the first nearly-gapless telomere-to-telomere replication timing profiles in human, using the T2T-CHM13 genome assembly and sequencing data for five cell lines. …”
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    Telomere-to-telomere human DNA replication timing profiles
  18. 18
    “…With the arrival of telomere-to-telomere (T2T) assemblies of the human genome comes the computational challenge of efficiently and accurately constructing multiple genome alignments at an unprecedented scale. …”
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    Multiple genome alignment in the telomere-to-telomere assembly era
  19. 19
    “…A well-established marker of the aging process is the length of the protective cap at the ends of chromosomes, called telomeres. Telomeres shorten with each cell division and with increasing chronological age and short telomeres have been associated with a range of age-related diseases. …”
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    Do Telomeres Adapt to Physiological Stress? Exploring the Effect of Exercise on Telomere Length and Telomere-Related Proteins
  20. 20
    por Roy, J. H. B.
    Publicado 1972
    Materias: “…Terneros Cría y desarrollo…”
    Libro
    El ternero.
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