Systematic analysis of SARS-CoV-2 infection of an ACE2-negative human airway cell

por Puray-Chavez, Maritza, LaPak, Kyle M., Schrank, Travis P., Elliott, Jennifer L., Bhatt, Dhaval P., Agajanian, Megan J., Jasuja, Ria, Lawson, Dana Q., Davis, Keanu, Rothlauf, Paul W., Liu, Zhuoming, Jo, Heejoon, Lee, Nakyung, Tenneti, Kasyap, Eschbach, Jenna E., Shema Mugisha, Christian, Cousins, Emily M., Cloer, Erica W., Vuong, Hung R., VanBlargan, Laura A., Bailey, Adam L., Gilchuk, Pavlo, Crowe, James E., Diamond, Michael S., Hayes, D. Neil, Whelan, Sean P.J., Horani, Amjad, Brody, Steven L., Goldfarb, Dennis, Major, M. Ben, Kutluay, Sebla B.
Publicado 2021

Resistance of SARS-CoV-2 variants to neutralization by antibodies induced in convalescent patients with COVID-19

por Kaku, Yu, Kuwata, Takeo, Zahid, Hasan Md, Hashiguchi, Takao, Noda, Takeshi, Kuramoto, Noriko, Biswas, Shashwata, Matsumoto, Kaho, Shimizu, Mikiko, Kawanami, Yoko, Shimura, Kazuya, Onishi, Chiho, Muramoto, Yukiko, Suzuki, Tateki, Sasaki, Jiei, Nagasaki, Yoji, Minami, Rumi, Motozono, Chihiro, Toyoda, Mako, Takahashi, Hiroshi, Kishi, Hiroto, Fujii, Kazuhiko, Tatsuke, Tsuneyuki, Ikeda, Terumasa, Maeda, Yosuke, Ueno, Takamasa, Koyanagi, Yoshio, Iwagoe, Hajime, Matsushita, Shuzo
Publicado 2021

Antibody landscape against SARS-CoV-2 reveals significant differences between non-structural/accessory and structural proteins

por Li, Yang, Xu, Zhaowei, Lei, Qing, Lai, Dan-yun, Hou, Hongyan, Jiang, He-wei, Zheng, Yun-xiao, Wang, Xue-ning, Wu, Jiaoxiang, Ma, Ming-liang, Zhang, Bo, Chen, Hong, Yu, Caizheng, Xue, Jun-biao, Zhang, Hai-nan, Qi, Huan, Guo, Shu-juan, Zhang, Yandi, Lin, Xiaosong, Yao, Zongjie, Sheng, Huiming, Sun, Ziyong, Wang, Feng, Fan, Xionglin, Tao, Sheng-ce
Publicado 2021

A single intranasal or intramuscular immunization with chimpanzee adenovirus-vectored SARS-CoV-2 vaccine protects against pneumonia in hamsters

por Bricker, Traci L., Darling, Tamarand L., Hassan, Ahmed O., Harastani, Houda H., Soung, Allison, Jiang, Xiaoping, Dai, Ya-Nan, Zhao, Haiyan, Adams, Lucas J., Holtzman, Michael J., Bailey, Adam L., Case, James Brett, Fremont, Daved H., Klein, Robyn, Diamond, Michael S., Boon, Adrianus C.M.
Publicado 2021

A SARS-CoV-2 neutralizing antibody selected from COVID-19 patients binds to the ACE2-RBD interface and is tolerant to most known RBD mutations

por Bertoglio, Federico, Fühner, Viola, Ruschig, Maximilian, Heine, Philip Alexander, Abassi, Leila, Klünemann, Thomas, Rand, Ulfert, Meier, Doris, Langreder, Nora, Steinke, Stephan, Ballmann, Rico, Schneider, Kai-Thomas, Roth, Kristian Daniel Ralph, Kuhn, Philipp, Riese, Peggy, Schäckermann, Dorina, Korn, Janin, Koch, Allan, Chaudhry, M. Zeeshan, Eschke, Kathrin, Kim, Yeonsu, Zock-Emmenthal, Susanne, Becker, Marlies, Scholz, Margitta, Moreira, Gustavo Marçal Schmidt Garcia, Wenzel, Esther Veronika, Russo, Giulio, Garritsen, Hendrikus S.P., Casu, Sebastian, Gerstner, Andreas, Roth, Günter, Adler, Julia, Trimpert, Jakob, Hermann, Andreas, Schirrmann, Thomas, Dübel, Stefan, Frenzel, André, Van den Heuvel, Joop, Čičin-Šain, Luka, Schubert, Maren, Hust, Michael
Publicado 2021

Prevention and therapy of SARS-CoV-2 and the B.1.351 variant in mice

por Martinez, David R., Schäfer, Alexandra, Leist, Sarah R., Li, Dapeng, Gully, Kendra, Yount, Boyd, Feng, Joy Y., Bunyan, Elaine, Porter, Danielle P., Cihlar, Tomas, Montgomery, Stephanie A., Haynes, Barton F., Baric, Ralph S., Nussenzweig, Michel C., Sheahan, Timothy P.
Publicado 2021

Systemic IL-15, IFN-γ, and IP-10/CXCL10 signature associated with effective immune response to SARS-CoV-2 in BNT162b2 mRNA vaccine recipients

por Bergamaschi, Cristina, Terpos, Evangelos, Rosati, Margherita, Angel, Matthew, Bear, Jenifer, Stellas, Dimitris, Karaliota, Sevasti, Apostolakou, Filia, Bagratuni, Tina, Patseas, Dimitris, Gumeni, Sentiljana, Trougakos, Ioannis P., Dimopoulos, Meletios A., Felber, Barbara K., Pavlakis, George N.
Publicado 2021

The COVIDome Explorer researcher portal

por Sullivan, Kelly Daniel, Galbraith, Matthew Dominic, Kinning, Kohl Thomas, Bartsch, Kyle William, Levinsky, Nik Caldwell, Araya, Paula, Smith, Keith Patrick, Granrath, Ross Erich, Shaw, Jessica Rose, Baxter, Ryan Michael, Jordan, Kimberly Rae, Russell, Seth Aaron, Dzieciatkowska, Monika Ewa, Reisz, Julie Ann, Gamboni, Fabia, Cendali, Francesca Isabelle, Ghosh, Tusharkanti, Monte, Andrew Albert, Bennett, Tellen Demeke, Miller, Michael George, Hsieh, Elena Wen-Yuan, D’Alessandro, Angelo, Hansen, Kirk Charles, Espinosa, Joaquin Maximiliano
Publicado 2021

No evidence of human genome integration of SARS-CoV-2 found by long-read DNA sequencing

por Smits, Nathan, Rasmussen, Jay, Bodea, Gabriela O., Amarilla, Alberto A., Gerdes, Patricia, Sanchez-Luque, Francisco J., Ajjikuttira, Prabha, Modhiran, Naphak, Liang, Benjamin, Faivre, Jamila, Deveson, Ira W., Khromykh, Alexander A., Watterson, Daniel, Ewing, Adam D., Faulkner, Geoffrey J.
Publicado 2021

Long-term SARS-CoV-2-specific immune and inflammatory responses in individuals recovering from COVID-19 with and without post-acute symptoms

por Peluso, Michael J., Deitchman, Amelia N., Torres, Leonel, Iyer, Nikita S., Munter, Sadie E., Nixon, Christopher C., Donatelli, Joanna, Thanh, Cassandra, Takahashi, Saki, Hakim, Jill, Turcios, Keirstinne, Janson, Owen, Hoh, Rebecca, Tai, Viva, Hernandez, Yanel, Fehrman, Emily A., Spinelli, Matthew A., Gandhi, Monica, Trinh, Lan, Wrin, Terri, Petropoulos, Christos J., Aweeka, Francesca T., Rodriguez-Barraquer, Isabel, Kelly, J. Daniel, Martin, Jeffrey N., Deeks, Steven G., Greenhouse, Bryan, Rutishauser, Rachel L., Henrich, Timothy J.
Publicado 2021

Convergent antibody responses to the SARS-CoV-2 spike protein in convalescent and vaccinated individuals

por Chen, Elaine C., Gilchuk, Pavlo, Zost, Seth J., Suryadevara, Naveenchandra, Winkler, Emma S., Cabel, Carly R., Binshtein, Elad, Chen, Rita E., Sutton, Rachel E., Rodriguez, Jessica, Day, Samuel, Myers, Luke, Trivette, Andrew, Williams, Jazmean K., Davidson, Edgar, Li, Shuaizhi, Doranz, Benjamin J., Campos, Samuel K., Carnahan, Robert H., Thorne, Curtis A., Diamond, Michael S., Crowe, James E.
Publicado 2021

One-shot identification of SARS-CoV-2 S RBD escape mutants using yeast screening

por Francino-Urdaniz, Irene M., Steiner, Paul J., Kirby, Monica B., Zhao, Fangzhu, Haas, Cyrus M., Barman, Shawn, Rhodes, Emily R., Leonard, Alison C., Peng, Linghang, Sprenger, Kayla G., Jardine, Joseph G., Whitehead, Timothy A.
Publicado 2021

Acute SARS-CoV-2 infection is associated with an increased abundance of bacterial pathogens, including Pseudomonas aeruginosa in the nose

por Rhoades, Nicholas S., Pinski, Amanda N., Monsibais, Alisha N., Jankeel, Allen, Doratt, Brianna M., Cinco, Isaac R., Ibraim, Izabela, Messaoudi, Ilhem
Publicado 2021

Combining spike- and nucleocapsid-based vaccines improves distal control of SARS-CoV-2

por Dangi, Tanushree, Class, Jacob, Palacio, Nicole, Richner, Justin M., Penaloza MacMaster, Pablo
Publicado 2021

The nucleotide addition cycle of the SARS-CoV-2 polymerase

por Bera, Subhas Chandra, Seifert, Mona, Kirchdoerfer, Robert N., van Nies, Pauline, Wubulikasimu, Yibulayin, Quack, Salina, Papini, Flávia S., Arnold, Jamie J., Canard, Bruno, Cameron, Craig E., Depken, Martin, Dulin, David
Publicado 2021

The neutralization potency of anti-SARS-CoV-2 therapeutic human monoclonal antibodies is retained against viral variants

por Makdasi, Efi, Zvi, Anat, Alcalay, Ron, Noy-Porat, Tal, Peretz, Eldar, Mechaly, Adva, Levy, Yinon, Epstein, Eyal, Chitlaru, Theodor, Tennenhouse, Ariel, Aftalion, Moshe, Gur, David, Paran, Nir, Tamir, Hadas, Zimhony, Oren, Weiss, Shay, Mandelboim, Michal, Mendelson, Ella, Zuckerman, Neta, Nemet, Ital, Kliker, Limor, Yitzhaki, Shmuel, Shapira, Shmuel C., Israely, Tomer, Fleishman, Sarel J., Mazor, Ohad, Rosenfeld, Ronit
Publicado 2021

Profiling CD8(+) T cell epitopes of COVID-19 convalescents reveals reduced cellular immune responses to SARS-CoV-2 variants

por Zhang, Hang, Deng, Shasha, Ren, Liting, Zheng, Peiyi, Hu, Xiaowen, Jin, Tengchuan, Tan, Xu
Publicado 2021

Broad cross-reactivity across sarbecoviruses exhibited by a subset of COVID-19 donor-derived neutralizing antibodies

por Jette, Claudia A., Cohen, Alexander A., Gnanapragasam, Priyanthi N.P., Muecksch, Frauke, Lee, Yu E., Huey-Tubman, Kathryn E., Schmidt, Fabian, Hatziioannou, Theodora, Bieniasz, Paul D., Nussenzweig, Michel C., West, Anthony P., Keeffe, Jennifer R., Bjorkman, Pamela J., Barnes, Christopher O.
Publicado 2021

A molecular sensor determines the ubiquitin substrate specificity of SARS-CoV-2 papain-like protease

por Patchett, Stephanie, Lv, Zongyang, Rut, Wioletta, Békés, Miklos, Drag, Marcin, Olsen, Shaun K., Huang, Tony T.
Publicado 2021

Potent neutralization of SARS-CoV-2 variants of concern by an antibody with an uncommon genetic signature and structural mode of spike recognition

por Kramer, Kevin J., Johnson, Nicole V., Shiakolas, Andrea R., Suryadevara, Naveenchandra, Periasamy, Sivakumar, Raju, Nagarajan, Williams, Jazmean K., Wrapp, Daniel, Zost, Seth J., Walker, Lauren M., Wall, Steven C., Holt, Clinton M., Hsieh, Ching-Lin, Sutton, Rachel E., Paulo, Ariana, Nargi, Rachel S., Davidson, Edgar, Doranz, Benjamin J., Crowe, James E., Bukreyev, Alexander, Carnahan, Robert H., McLellan, Jason S., Georgiev, Ivelin S.
Publicado 2021