IgG targeting distinct seasonal coronavirus- conserved SARS-CoV-2 spike subdomains correlates with differential COVID-19 disease outcomes

por Garrido, Jose L., Medina, Matías A., Bravo, Felipe, McGee, Sarah, Fuentes-Villalobos, Francisco, Calvo, Mario, Pinos, Yazmin, Bowman, James W., Bahl, Christopher D., Barria, Maria Ines, Brachman, Rebecca A., Alvarez, Raymond A.
Publicado 2022

Functional properties of the spike glycoprotein of the emerging SARS-CoV-2 variant B.1.1.529

por Wang, Qian, Anang, Saumya, Iketani, Sho, Guo, Yicheng, Liu, Lihong, Katsamba, Phinikoula S., Shapiro, Lawrence, Ho, David D., Sodroski, Joseph G.
Publicado 2022

Single-cell RNA sequencing reveals immunological rewiring at the maternal-fetal interface following asymptomatic/mild SARS-CoV-2 infection

por Sureshchandra, Suhas, Zulu, Michael Z., Doratt, Brianna M., Jankeel, Allen, Tifrea, Delia, Edwards, Robert, Rincon, Monica, Marshall, Nicole E., Messaoudi, Ilhem
Publicado 2022

Baricitinib attenuates the proinflammatory phase of COVID-19 driven by lung-infiltrating monocytes

por Dobosh, Brian, Zandi, Keivan, Giraldo, Diego Moncada, Goh, Shu Ling, Musall, Kathryn, Aldeco, Milagros, LeCher, Julia, Giacalone, Vincent D., Yang, Junkai, Eddins, Devon J., Bhasin, Manoj, Ghosn, Eliver, Sukhatme, Vikas, Schinazi, Raymond F., Tirouvanziam, Rabindra
Publicado 2022

Broadly recognized, cross-reactive SARS-CoV-2 CD4 T cell epitopes are highly conserved across human coronaviruses and presented by common HLA alleles

por Becerra-Artiles, Aniuska, Calvo-Calle, J. Mauricio, Co, Mary Dawn, Nanaware, Padma P., Cruz, John, Weaver, Grant C., Lu, Liying, Forconi, Catherine, Finberg, Robert W., Moormann, Ann M., Stern, Lawrence J.
Publicado 2022

Spatial region-resolved proteome map reveals mechanism of COVID-19-associated heart injury

por Leng, Ling, Ma, Jie, Zhang, Pei-Pei, Xu, Si-Chi, Li, Xiao, Jin, Ye, Cai, Jun, Tang, Rui, Zhao, Lei, He, Zhi-Cheng, Li, Man-Sheng, Zhang, Hui, Zhou, Liang-Rui, Wu, Zhi-Hong, Li, Tian-Ran, Zhu, Yun-Ping, Wang, Yu-Jie, Wu, Hai-Bo, Ping, Yi-Fang, Yao, Xiao-Hong, Zhu, Chu-Hong, Guo, Hai-Tao, Tan, Le-Yong, Liang, Zhi-Yong, Bian, Xiu-Wu, Zhang, Shu-Yang
Publicado 2022

Emerging viruses: Cross-species transmission of coronaviruses, filoviruses, henipaviruses, and rotaviruses from bats

por Tian, Jin, Sun, Jiumeng, Li, Dongyan, Wang, Ningning, Wang, Lifang, Zhang, Chang, Meng, Xiaorong, Ji, Xiang, Suchard, Marc A., Zhang, Xu, Lai, Alexander, Su, Shuo, Veit, Michael
Publicado 2022

Cryo-EM structures of SARS-CoV-2 Omicron BA.2 spike

por Stalls, Victoria, Lindenberger, Jared, Gobeil, Sophie M.-C., Henderson, Rory, Parks, Rob, Barr, Maggie, Deyton, Margaret, Martin, Mitchell, Janowska, Katarzyna, Huang, Xiao, May, Aaron, Speakman, Micah, Beaudoin, Esther, Kraft, Bryan, Lu, Xiaozhi, Edwards, Robert J., Eaton, Amanda, Montefiori, David C., Williams, Wilton B., Saunders, Kevin O., Wiehe, Kevin, Haynes, Barton F., Acharya, Priyamvada
Publicado 2022

Superimmunity by pan-sarbecovirus nanobodies

por Xiang, Yufei, Huang, Wei, Liu, Hejun, Sang, Zhe, Nambulli, Sham, Tubiana, Jérôme, Williams, Kevin L., Duprex, W. Paul, Schneidman-Duhovny, Dina, Wilson, Ian A., Taylor, Derek J., Shi, Yi
Publicado 2022

COVID-19 vaccination elicits an evolving, cross-reactive antibody response to epitopes conserved with endemic coronavirus spike proteins

por Elko, Evan A., Nelson, Georgia A., Mead, Heather L., Kelley, Erin J., Carvalho, Sophia T., Sarbo, Nathan G., Harms, Caroline E., Le Verche, Virginia, Cardoso, Angelo A., Ely, Jennifer L., Boyle, Annalee S., Piña, Alejandra, Henson, Sierra N., Rahee, Fatima, Keim, Paul S., Celona, Kimberly R., Yi, Jinhee, Settles, Erik W., Bota, Daniela A., Yu, George C., Morris, Sheldon R., Zaia, John A., Ladner, Jason T., Altin, John A.
Publicado 2022

Temporal associations of B and T cell immunity with robust vaccine responsiveness in a 16-week interval BNT162b2 regimen

por Nayrac, Manon, Dubé, Mathieu, Sannier, Gérémy, Nicolas, Alexandre, Marchitto, Lorie, Tastet, Olivier, Tauzin, Alexandra, Brassard, Nathalie, Lima-Barbosa, Raphaël, Beaudoin-Bussières, Guillaume, Vézina, Dani, Gong, Shang Yu, Benlarbi, Mehdi, Gasser, Romain, Laumaea, Annemarie, Prévost, Jérémie, Bourassa, Catherine, Gendron-Lepage, Gabrielle, Medjahed, Halima, Goyette, Guillaume, Ortega-Delgado, Gloria-Gabrielle, Laporte, Mélanie, Niessl, Julia, Gokool, Laurie, Morrisseau, Chantal, Arlotto, Pascale, Richard, Jonathan, Bélair, Justin, Prat, Alexandre, Tremblay, Cécile, Martel-Laferrière, Valérie, Finzi, Andrés, Kaufmann, Daniel E.
Publicado 2022

SARS-CoV-2 susceptibility and COVID-19 disease severity are associated with genetic variants affecting gene expression in a variety of tissues

por D’Antonio, Matteo, Nguyen, Jennifer P., Arthur, Timothy D., Matsui, Hiroko, D’Antonio-Chronowska, Agnieszka, Frazer, Kelly A.
Publicado 2022

Longitudinal analyses reveal distinct immune response landscapes in lung and intestinal tissues from SARS-CoV-2-infected rhesus macaques

por Zheng, Huiwen, Chen, Yanli, Li, Jing, Li, Heng, Zhao, Xin, Li, Jiali, Yang, Fengmei, Li, Yanyan, Liu, Changkun, Qin, Li, Zuo, Yuanyuan, Zhang, Qian, He, Zhanlong, Shi, Haijing, Li, Qihan, Liu, Longding
Publicado 2022

Early IFNβ secretion determines variable downstream IL-12p70 responses upon TLR4 activation

por Posseme, Celine, Llibre, Alba, Charbit, Bruno, Bondet, Vincent, Rouilly, Vincent, Saint-André, Violaine, Boussier, Jeremy, Bergstedt, Jacob, Smith, Nikaïa, Townsend, Liam, Sugrue, Jamie A., Ní Cheallaigh, Clíona, Conlon, Niall, Rotival, Maxime, Kobor, Michael S., Mottez, Estelle, Pol, Stanislas, Patin, Etienne, Albert, Matthew L., Quintana-Murci, Lluis, Duffy, Darragh
Publicado 2022

Amelioration of SARS-CoV-2 infection by ANO6 phospholipid scramblase inhibition

por Sim, Ju-Ri, Shin, Dong Hoon, Park, Pil-Gu, Park, So-Hyeon, Bae, Joon-Yong, Lee, Youngchae, Kang, Dha-Yei, Kim, Ye Jin, Aum, Sowon, Noh, Shin Hye, Hwang, Su Jin, Cha, Hye-Ran, Kim, Cheong Bi, Ko, Si Hwan, Park, Sunghoon, Jeon, Dongkyu, Cho, Sungwoo, Lee, Gee Eun, Kim, Jeonghun, Moon, Young-hye, Kim, Jae-Ouk, Nam, Jae-Sung, Kim, Chang-Hoon, Moon, Sungmin, Chung, Youn Wook, Park, Man-Seong, Ryu, Ji-Hwan, Namkung, Wan, Lee, Jae Myun, Lee, Min Goo
Publicado 2022

The generation of stem cell-like memory cells early after BNT162b2 vaccination is associated with durability of memory CD8(+) T cell responses

por Jung, Sungmin, Jung, Jae Hyung, Noh, Ji Yun, Kim, Woo-Joong, Yoon, Soo-Young, Jung, Jongtak, Kim, Eu Suk, Kim, Hong Bin, Cheong, Hee Jin, Kim, Woo Joo, Park, Su-Hyung, Song, Kyoung-Ho, Song, Joon Young, Shin, Eui-Cheol
Publicado 2022

Plasmacytoid dendritic cells during COVID-19: Ally or adversary?

por Van der Sluis, Renée Marije, Holm, Christian Kanstrup, Jakobsen, Martin Roelsgaard
Publicado 2022

Multiplexed LNP-mRNA vaccination against pathogenic coronavirus species

por Peng, Lei, Fang, Zhenhao, Renauer, Paul A., McNamara, Andrew, Park, Jonathan J., Lin, Qianqian, Zhou, Xiaoyu, Dong, Matthew B., Zhu, Biqing, Zhao, Hongyu, Wilen, Craig B., Chen, Sidi
Publicado 2022

Vaccine-associated enhanced respiratory pathology in COVID-19 hamsters after T(H)2-biased immunization

por Ebenig, Aileen, Muraleedharan, Samada, Kazmierski, Julia, Todt, Daniel, Auste, Arne, Anzaghe, Martina, Gömer, André, Postmus, Dylan, Gogesch, Patricia, Niles, Marc, Plesker, Roland, Miskey, Csaba, Gellhorn Serra, Michelle, Breithaupt, Angele, Hörner, Cindy, Kruip, Carina, Ehmann, Rosina, Ivics, Zoltan, Waibler, Zoe, Pfaender, Stephanie, Wyler, Emanuel, Landthaler, Markus, Kupke, Alexandra, Nouailles, Geraldine, Goffinet, Christine, Brown, Richard J.P., Mühlebach, Michael D.
Publicado 2022

SARS-CoV-2 vaccine-induced antibody and T cell response in SARS-CoV-1 survivors

por Duan, Li-Jun, Cui, Xiao-Ming, Zhu, Ka-Li, Yao, Lin, Wang, Guo-Lin, Cao, Wu-Chun, Ma, Mai-Juan
Publicado 2022